The mechanisms of propofol-induced vascular relaxation and modulation by perivascular adipose tissue and endothelium

Anesthesia and Analgesia

Volumn 112, Issue 6, 2011, Pages 1339-1345

  Kassam, Saira I ^a   Lu, Chao ^a   Buckley, Norman ^a   Lee, Robert M K W ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; CATALASE; GLIBENCLAMIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; POTASSIUM CHLORIDE; PROPOFOL; TETRYLAMMONIUM;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; MALE; NONHUMAN; PERIVASCULAR ADIPOSE TISSUE; PRIORITY JOURNAL; RAT; THORACIC AORTA; VASCULAR ENDOTHELIUM; VASCULAR TISSUE; VASOCONSTRICTION; VASODILATATION;

EID: 79958142036     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e318215e094     Document Type: Article

References (36)

1. Langley MS, Heel RC. Propofol. A review of its pharmacodynamic and pharmacokinetic properties and use as an intravenous anaesthetic. Drugs 1988;35:334-72
2. Devlin JW, Roberts RJ. Pharmacology of commonly used analgesics and sedatives in the ICU: benzodiazepines, propofol, and opioids. Crit Care Clin 2009;25:431-49
3. Chang KS, Davis RF. Propofol produces endothelium-independent vasodilation and may act as a Ca2+ channel blocker. Anesth Analg 1993;76:24-32 (Pubitemid 23094807)
4. Park KW, Dai HB, Lowenstein E, Sellke FW. Propofol-associated dilation of rat distal coronary arteries is mediated by multiple substances, including endothelium-derived nitric oxide. Anesth Analg 1995;81:1191-6
5. Sebel PS, Lowdon JD. Propofol: a new intravenous anesthetic. Anesthesiology 1989;71:260-77 (Pubitemid 19203342)
6. Wallerstedt SM, Tornebrandt K, Bodelsson M. Relaxant effects of propofol on human omental arteries and veins. Br J Anaesth 1998;80:655-9 (Pubitemid 28224928)
7. Foex P, Sear JW, Diedericks J. Cardiovascular effects of propofol. In: Prys-Roberts C, ed. Focus on Infusion: Intravenous Anaesthesia. London: Current Medical Literature Ltd., 1991:1-9
8. Neukirchen M, Kienbaum P. Sympathetic nervous system: evaluation and importance for clinical general anesthesia. Anesthesiology 2008;109:1113-31
9. Furchgott RF, Vanhoutte PM. Endothelium-derived relaxing and contracting factors. FASEB J 1989;3:2007-18 (Pubitemid 19187609)
10. Kamitani K, Yamazaki M, Yukitaka M, Ito Y, Momose Y. Effects of propofol on isolated rabbit mesenteric arteries and veins. Br J Anaesth 1995;75:457-61
11. Luo AL, Luo T, Liu XY. Propofol evokes endothelium-independent relaxation in rabbit thoracic aorta strips: role of K+ channels. Chin Med J (Engl) 2005;118:1388-91 (Pubitemid 41223178)
12. Mimaroglu C, Utkan T, Kaya T, Kafali H, Sarioglu Y. Effects of propofol on vascular smooth muscle function in isolated rat aorta. Methods Find Exp Clin Pharmacol 1994;16:257-61 (Pubitemid 24163892)
13. Xuan YT, Glass PS. Propofol regulation of calcium entry pathways in cultured A10 and rat aortic smooth muscle cells. Br J Pharmacol 1996;117:5-12 (Pubitemid 26030246)
14. Gacar N, Gok S, Kalyoncu NI, Ozen I, Soykan N, Akturk G. The effect of edothelium on the response to propofol on bovine coronary artery rings. Acta Anaesthesiol Scand 1995;39:1080-3
15. Yamanoue T, Brum JM, Estafanous FG. Vasodilation and mechanism of action of propofol in porcine coronary artery. Anesthesiology 1994;81:443-51 (Pubitemid 24320636)
16. Verlohren S, Dubrovska G, Tsang SY, Essin K, Luft FC, Huang Y, Gollasch M. Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries. Hypertension 2004; 44:271-6 (Pubitemid 39167221)
17. Gao YJ, Holloway AC, Zeng ZH, Lim GE, Petrik JJ, Foster WG, Lee RMKW. Prenatal exposure to nicotine causes postnatal obesity and altered perivascular adipose tissue function. Obes Res 2005;13:687-92
18. Lohn M, Dubrovska G, Lauterbach B, Luft FC, Gollasch M, Sharma AM. Periadventitial fat releases a vascular relaxing factor. FASEB J 2002;16:1057-63 (Pubitemid 34753512)
19. Lu C, Su LY, Gao YJ, Lee RMKW. Modulation of vein function by perivascular adipose tissue. Eur J Pharmacol 2011;657:111-6
20. Gao YJ, Zeng ZH, Teoh K, Sharma AM, Abouzahr L, Cybulsky I, Lamy A, Semelhago L, Lee RMKW. Perivascular adipose tissue modulates vascular function in the human internal thoracic artery. J Thorac Cardiovasc Surg 2005;130:1130-6 (Pubitemid 41427351)
21. Galvez-Prieto B, Dubrovska G, Cano MV, Delgado M, Aran-guez I, Gonzalez MC, Ruiz-Gayo M, Gollasch M, Fernandez-Alfonso MS. A reduction in the amount and anti-contractile effect of periadventitial mesenteric adipose tissue precedes hypertension development in spontaneously hypertensive rats. Hypertens Res 2008;31:1415-23
22. Gao YJ, Holloway AC, Su LY, Takemori K, Lu C, Lee RM. Effects of fetal and neonatal exposure to nicotine on blood pressure and perivascular adipose tissue function in adult life. Eur J Pharmacol 2008;590:264-8
23. Lu C, Su LY, Lee RMKW, Gao YJ. Alterations in perivascular adipose tissue structure and function in hypertension. Eur J Pharmacol 2011;656:68-73
24. Lee RMKW, Lu C, Su LY, Werstuck G, Gao YJ. Effects of hyperglycemia on the modulation of vascular function by perivascular adipose tissue. J Hypertens 2009;27:118-31
25. Gao YJ, Lu C, Su LY, Sharma AM, Lee RMKW. Modulation of vascular function by perivascular adipose tissue: the role of endothelium and hydrogen peroxide. Br J Pharmacol 2007; 151:323-31 (Pubitemid 46842669)
26. Lee RMKW, Lu C, Su LY, Gao YJ. Endothelium-dependent relaxation factor released by perivascular adipose tissue. J Hypertens 2009;27:782-90
27. Park WK, Lynch C III, Johns RA. Effects of propofol and thiopental in isolated rat aorta and pulmonary artery. Anesthesiology 1992;77:956-63
28. Petros AJ, Bogle RG, Pearson JD. Propofol stimulates nitric oxide release from cultured porcine aortic endothelial cells. Br J Pharmacol 1993;109:6-7 (Pubitemid 23113792)
29. Mistry DK, Garland CJ. Nitric oxide (NO)-induced activation of large conductance Ca2+-dependent K+ channels (BK(Ca)) in smooth muscle cells isolated from the rat mesenteric artery. Br J Pharmacol 1998;124:1131-40 (Pubitemid 28333935)
30. Nagakawa T, Yamazaki M, Hatakeyama N, Stekiel TA. The mechanisms of propofol-mediated hyperpolarization of in situ rat mesenteric vascular smooth muscle. Anesth Analg 2003;97:1639-45 (Pubitemid 37475114)
31. Gao YJ, Lee RM. Hydrogen peroxide is an endothelium-dependent contracting factor in rat renal artery. Br J Pharmacol 2005;146:1061-8 (Pubitemid 41785318)
32. Yamakage M, Hirshman CA, Croxton TL. Inhibitory effects of thiopental, ketamine, and propofol on voltage-dependent Ca2+ channels in porcine tracheal smooth muscle cells. Anesthesiology 1995;83:1274-82
33. Masui K, Upton RN, Doufas AG, Coetzee JF, Kazama T, Mortier EP, Struys MM. The performance of compartmental and physiologically based recirculatory pharmacokinetic models for propofol: a comparison using bolus, continuous, and target-controlled infusion data. Anesth Analg 2010;111:368-79
34. Grounds RM, Twigley AJ, Carli F, Whitwam JG, Morgan M. The haemodynamic effects of intravenous induction. Comparison of the effects of thiopentone and propofol. Anaesthesia 1985;40:735-40 (Pubitemid 15232254)
35. Van AH, Meinshausen E, Prien T, Brussel T, Heinecke A, Lawin P. The influence of fentanyl and tracheal intubation on the hemodynamic effects of anesthesia induction with propofol/N2O in humans. Anesthesiology 1988;68:157-63 (Pubitemid 18059837)
36. Takemori K, Gao YJ, Ding L, Lu C, Su LY, An WS, Vinson C, Lee RMKW. Elevated blood pressure in transgenic lipoatro-phic mice and altered vascular function. Hypertension 2007; 49:365-72 (Pubitemid 46143014)