K182G substitution in DevR or C 8G mutation in the Dev box impairs protein-DNA interaction and abrogates DevR-mediated gene induction in Mycobacterium tuberculosis

FEBS Journal

Volumn 278, Issue 12, 2011, Pages 2131-2139

  Gupta, Rajesh Kumar ^a   Chauhan, Santosh ^a,b   Tyagi, Jaya Sivaswami ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

DevR (or DosR); DNA protein interaction; Mycobacterium tuberculosis

Indexed keywords

LYSINE; MESSENGER RNA; PROTEIN DEVR; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DNA FOOTPRINTING; FDXA GENE; GENE EXPRESSION; GENE INDUCTION; MUTATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; TRANSCRIPTION INITIATION SITE;

AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; DNA, BACTERIAL; GENES, BACTERIAL; HOST-PATHOGEN INTERACTIONS; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; MYCOBACTERIUM TUBERCULOSIS; PROMOTER REGIONS, GENETIC; REGULON;

MYCOBACTERIUM TUBERCULOSIS;

EID: 79958138513     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08130.x     Document Type: Article

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