Expression of leukemia inhibitory factor in the cerebrospinal fluid of patients with multiple sclerosis

Journal of Clinical Neuroscience

Volumn 18, Issue 7, 2011, Pages 951-954

  Mashayekhi, Farhad ^a   Salehi, Zivar ^a  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Cerebrospinal fluid; Leukemia inhibitory factor; Multiple sclerosis

Indexed keywords

LEUKEMIA INHIBITORY FACTOR;

ADULT; ARTICLE; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN EXPRESSION;

BIOLOGICAL MARKERS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LEUKEMIA INHIBITORY FACTOR; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, RELAPSING-REMITTING;

EID: 79958122821     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2010.12.031     Document Type: Article

References (29)

1. Lowis GW. The social epidemiology of multiple sclerosis. Sci Total Environ 1990;90:163-90.
2. Duquette P, Pleines J, Girard M, et al. The increased susceptibility of women to multiple sclerosis. Can J Neurol Sci 1992;19:466-71.
3. Swingler RJ, Compston D. The distribution of multiple sclerosis in the United Kingdom. J Neurol Neurosurg Psychiatry 1986;49:1115-24. (Pubitemid 16028692)
4. Sadovnick AD, Ebers GC. Epidemiology of multiple sclerosis: a critical overview. Can J Neurol Sci 1993;20:17-29. (Pubitemid 23056941)
5. Bulman DE, Sadovnick AD, Ebers GC. Age of onset in siblings concordant for multiple sclerosis. Brain 1991;114:937-50.
6. Cheema SS, Arumugam D, Murray SS, et al. Leukemia inhibitory factor maintains choline acetyltransferase expression in vivo. Neuroreport 1998;16:363-6. (Pubitemid 28109188)
7. Butzkueven H, Zhang JG, Soilu-Hanninen M, et al. LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival. Nat Med 2002;8:613-9. (Pubitemid 34633440)
8. Butzkueven H, Emery B, Cipriani T, et al. Endogenous leukemia inhibitory factor production limits autoimmune demyelination and oligodendrocyte loss. Glia 2006;53:696-703.
9. Bauer S, Patterson PH. Leukemia inhibitory factor promotes neural stem cell self-renewal in the adult brain. J Neurosci 2006;26:12089-99. (Pubitemid 44772119)
10. Ihle JN. Cytokine receptor signalling. Nature 1995;377:591-4.
11. Gearing DP, Thut CJ, VandeBos T, et al. Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. EMBO J 1991;10:2839-48. (Pubitemid 21905301)
12. Gearing DP, VandenBos T, Beckmann MP, et al. Reconstitution of high affinity leukaemia inhibitory factor (LIF) receptors in haemopoietic cells transfected with the cloned human LIF receptor. Ciba Found Symp 1992;167:245-55.
13. Soilu-Hänninen M, Broberg E, Röyttä M, et al. Expression of LIF and LIF receptor beta in Alzheimer's and Parkinson's diseases. Acta Neurol Scand 2010;121:44-50.
14. Holmberg KH, Patterson PH. Leukemia inhibitory factor is a key regulator of astrocytic, microglial and neuronal responses in a low-dose pilocarpine injury model. Brain Res 2006;1075:26-35.
15. Slaets H, Hendriks JJ, Stinissen P, et al. Therapeutic potential of LIF in multiple sclerosis. Trends Mol Med 2010;16:493-500.
16. Waring P, Wycherley K, Cary D, et al. Leukemia inhibitory factor levels are elevated in septic shock and various inflammatory body fluids. J Clin Invest 1992;90:2031-7.
17. Murase K, Nabeshima T, Robitaille Y, et al. NGF level of is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with Alzheimer's disease. Biochem Biophys Res Commun 1993;28:198-203. (Pubitemid 23199932)
18. Salehi Z, Mashayekhi F, Naji M. Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease. Biofactors 2008;33:99-106.
19. Mashayekhi F, Mirzajani E, Naji M, et al. Expression of insulin-like growth factor-1 and insulin-like growth factor binding proteins in the serum and cerebrospinal fluid of patients with Parkinson's disease. J Clin Neurosci 2010;17:623-7.
20. Waring P, Wycherley K, Cary D, et al. Leukemia inhibitory factor levels are elevated in septic shock and various inflammatory body fluids. J Clin Invest 1992;90:2031-7.
21. Taupin JL, Pitard V, Dechanet J, et al. Leukemia inhibitory factor: part of a large ingathering family. Int Rev Immunol 1998;16:397-426. (Pubitemid 28102262)
22. Brown MA, Metcalf D, Gough NM. Leukaemia inhibitory factor and interleukin 6 are expressed at very low levels in the normal adult mouse and are induced by inflammation. Cytokine 1994;6:300-9. (Pubitemid 24263873)
23. Gard AL, Gavin E, Solodushko V, et al. Cardiotrophin-1 in choroid plexus and the cerebrospinal fluid circulatory system. Neuroscience 2004;127:43-52. (Pubitemid 38829150)
24. Aloisi F, Rosa S, Testa U, et al. Regulation of leukemia inhibitory factor synthesis in cultured human astrocytes. J Immunol 1994;15:5022-31. (Pubitemid 24139097)
25. Giess R, Holtmann B, Braga M, et al. Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene. Am J Hum Genet 2002;70:1277-86. (Pubitemid 34450577)
26. Rensink AA, Gellekink H, Otte-Höller I, et al. Expression of the cytokine leukemia inhibitory factor and pro-apoptotic insulin-like growth factor binding protein-3 in Alzheimer's disease. Acta Neuropathol 2002;104:525-33. (Pubitemid 36075420)
27. Hendriks JJ, Slaets H, Carmans S, et al. Leukemia inhibitory factor modulates production of inflammatory mediators and myelin phagocytosis by macrophages. J Neuroimmunol 2008;15:52-7.
28. Vanderocht J, Hellings N, Hendriks JJ, et al. Leukemia inhibitory factor is produced by myelin-reactive T cells from multiple sclerosis patients and protects against tumor necrosis factor-alpha-induced oligodendrocyte apoptosis. J Neurosci Res 2006;83:763-74.
29. Simamura E, Shimada H, Higashi N, et al. Maternal leukemia inhibitory factor (LIF) promotes fetal neurogenesis via a LIF-ACTH-LIF signaling relay pathway. Endocrinology 2010;151:1853-62.