Enantioselective organocatalytic aryloxylation of β-keto esters

Synthesis

Volumn , Issue 12, 2011, Pages 1880-1886

  Greenaway, Kevin ^a   Dambruoso, Paolo ^a   Ferrali, Alessandro ^a   Hazelwood, Andrew J ^b   Sladojevich, Filippo ^c   Dixon, Darren J ^c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

keto ester; aryloxylation; dioxins; organocatalysis; quinones

Indexed keywords

ARYLOXYLATION; DIOXINS; KETO ESTER; ORGANOCATALYSIS; QUINONES;

CATALYSIS; ESTERIFICATION; ORGANIC POLLUTANTS; REACTION KINETICS;

ESTERS;

BETA KETO ESTER DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; ESTER DERIVATIVE; ETHYL 5 BROMO 7 TERT BUTYL 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; ETHYL 5,6,7,8 TETRABROMO 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; ETHYL 5,6,7,8 TETRACHLORO 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; ETHYL 6 TERT BUTYL 8 CHLORO 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; ETHYL 6,8 DI TERT BUTYL 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; ETHYL 7 TERT BUTYL 5 CHLORO 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; ETHYL 7 TERT BUTYL 9 CHLORO 10A HYDROXY 1,3,4,10A TETRAHYDRO 2H DIBENZO[B,E][1,4]DIOXIN 4A CARBOXYLIC ACID; ETHYL 8 BROMO 6 TERT BUTYL 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; ETHYL 8 TERT BUTYL 6 CHLORO 10A HYDROXY 1,3,4,10A TETRAHYDRO 2H DIBENZO[B,E][1,4]DIOXIN 4A CARBOXYLIC ACID; METHYL 5 BROMO 7 TERT BUTYL 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; METHYL 5,6,7,8 TETRABROMO 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; METHYL 5,6,7,8 TETRACHLORO 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; METHYL 6 TERT BUTYL 8 CHLORO 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; METHYL 6,7,8,9 TETRABROMO 10A HYDROXY 1,3,4,10A TETRAHYDRO 2H DIBENZO[B,E][1,4]DIOXIN 4A CARBOXYLIC ACID; METHYL 6,8 DI TERT BUTYL 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; METHYL 7 TERT BUTYL 5 CHLORO 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; METHYL 7 TERT BUTYL 9 CHLORO 10A HYDROXY 1,3,4,10A TETRAHYDRO 2H DIBENZO[B,E][1,4]DIOXIN 4A CARBOXYLIC ACID; METHYL 7,9 DI TERT BUTYL 10A HYDROXY 1,3,4,10A TETRAHYDRO 2H DIBENZO[B,E][1,4]DIOXIN 4A CARBOXYLIC ACID; METHYL 8 BROMO 6 TERT BUTYL 9A HYDROXY 1,2,3,9A TETRAHYDRO 3AH CYCLOPENTA[B][1,4]BENZODIOXIN 3A CARBOXYLIC ACID; METHYL 8 TERT BUTYL 6 CHLORO 10A HYDROXY 1,3,4,10A TETRAHYDRO 2H DIBENZO[B,E][1,4]DIOXIN 4A CARBOXYLIC ACID; QUINONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ARYLOXYLATION; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; PROCESS OPTIMIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; X RAY DIFFRACTION;

EID: 79958121265     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1260059     Document Type: Article

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