Passive immunization with Leptospira LPS-specific agglutinating but not non-agglutinating monoclonal antibodies protect guinea pigs from fatal pulmonary hemorrhages induced by serovar Copenhageni challenge

Vaccine

Volumn 29, Issue 27, 2011, Pages 4431-4434

  Challa, Sreerupa ^a   Nally, Jarlath E ^b   Jones, Carroll ^c   Sheoran, Abhineet S ^a  

^a TUFTS UNIVERSITY   (United States)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

^c IDEXX LABORATORIES   (United States)

Author keywords

Antibody; Guinea pig; Leptospira; LPS; Pulmonary hemorrhage

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY L4C1; MONOCLONAL ANTIBODY L8H4; MONOCLONAL ANTIBODY L9B11; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ARTICLE; CONTROLLED STUDY; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; LUNG HEMORRHAGE; MALE; MOUSE; NONHUMAN; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; SEROTYPE;

AGGLUTINATION; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; DISEASE MODELS, ANIMAL; GUINEA PIGS; HEMORRHAGE; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOBLOTTING; LEPTOSPIRA INTERROGANS; LEPTOSPIROSIS; LIPOPOLYSACCHARIDES; LUNG DISEASES; MALE; MICE; SEROTYPING; WEIL DISEASE;

EID: 79958099136     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.04.041     Document Type: Article

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