Cytokine production from peripheral blood mononuclear cells and polymorphonuclear leukocytes in patients studied for suspected obstructive sleep apnea

Sleep and Breathing

Volumn 15, Issue 1, 2011, Pages 3-11

  Guasti, Luigina ^a   Marino, Franca ^a   Cosentino, Marco ^a   Maroni, Lorenzo ^a   Maresca, Andrea M ^a   Colombo, Fausto ^b   Maio, Ramona C ^a   Castiglioni, Luana ^a   Saporiti, Federica ^a   Loraschi, Anna ^a   Gaudio, Giovanni ^a   Bernasconi, Antonella ^b   Laurita, Emanuela ^a   Grandi, Anna M ^a   Venco, Achille ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

^b OSPEDALE DI CIRCOLO   (Italy)

Author keywords

Continuous positive airway pressure ventilation; Interleukin 8; Obstructive sleep apnea; Peripheral blood mononuclear cells; Polymorphonuclear leukocytes; Tumor necrosis factor

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; CALCIUM CHANNEL BLOCKING AGENT; CHOLESTEROL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; GLIBENCLAMIDE; GLIBENCLAMIDE PLUS METFORMIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 8; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; METFORMIN PLUS ROSIGLITAZONE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

APNEA HYPOPNEA INDEX; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DYSLIPIDEMIA; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERTENSION; LIPOPROTEIN BLOOD LEVEL; MALE; NEUTROPHIL; PERIPHERAL BLOOD MONONUCLEAR CELL; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SERUM; SLEEP APNEA SYNDROME; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGED; CONTINUOUS POSITIVE AIRWAY PRESSURE; CYTOKINES; FEMALE; HUMANS; INTERLEUKIN-8; MALE; MIDDLE AGED; MONOCYTES; NEUTROPHILS; REFERENCE VALUES; SLEEP APNEA, OBSTRUCTIVE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79958096953     PISSN: 15209512     EISSN: 15221709     Source Type: Journal    
DOI: 10.1007/s11325-009-0315-x     Document Type: Article

References (48)

1. JR Stradling JH Crosby 1991 Predictor and prevalence of OSA and snoring in 1001 middle aged men Thorax 46 85 90 2014507 10.1136/thx.46.2.85 1:STN:280:DyaK3M7psF2ksg%3D%3D
2. AB Newman FJ Nieto U Guidry BK Lind S Redline TG Pickering SF Quan Sleep Heart Health Study Research Group 2001 Relation of sleep-disordered breathing to cardiovascular disease risk factors: the sleep heart health study Am J of Epidemiol 154 50 59 10.1093/aje/154.1.50 1:STN:280:DC%2BD3MznvVGnsQ%3D%3D (Pubitemid 32565686)
3. PE Peppard T Young M Palta J Skatrud 2000 Prospective study of the association between sleep-disordered breathing and hypertension N Engl J Med 342 1378 1384 10805822 10.1056/NEJM200005113421901 1:STN:280:DC%2BD3c3kvVyhuw%3D%3D (Pubitemid 30262394)
4. AN Vgontzas DA Papanicolaou EO Bixler K Hopper A Lotsikas HM Lin A Kales GP Chrousos 2000 Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia J Clin Endocrinol Metab 85 1151 1158 10720054 10.1210/jc.85.3.1151 1:CAS:528:DC%2BD3cXisFOqsrs%3D (Pubitemid 32269364)
5. SF Quan BJ Gersh National Center on Sleep Disorders Research National Heart, Lung, and Blood Institute 2004 Cardiovascular consequences of sleep-disordered breathing: past, present and future: report of a workshop from the national center on sleep disorders research and the national heart, lung, and blood institute Circulation 109 951 957 10.1161/01.CIR.0000118216.84358.22 14993147 10.1161/01.CIR.0000118216.84358.22 (Pubitemid 38282845)
6. R Wolk VK Somers K Virend 2007 Sleep and the metabolic syndrome Exp Physiol 92 67 78 10.1113/expphysiol.2006.033787 17085678 10.1113/expphysiol. 2006.033787 (Pubitemid 46096254)
7. SR Coughlin L Mawdsley JA Mugarza PM Calverley JP Wilding 2004 Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome Eur Heart J 25 735 741 10.1016/j.ehj.2004.02. 021 15120883 10.1016/j.ehj.2004.02.021 (Pubitemid 38647933)
8. LA Bazzano Z Khan K Reynolds J He 2007 Effect of nocturnal nasal continuous positive airway pressure on blood pressure in obstructive sleep apnea Hypertension 50 417 423 10.1161/HYPERTENSIONAHA.106.085175 17548722 10.1161/HYPERTENSIONAHA.106.085175 1:CAS:528:DC%2BD2sXnsFOjsbg%3D (Pubitemid 47205794)
9. GK Hansson 2005 Inflammation, Atherosclerosis and coronary artery disease N Engl J Med 352 1685 1695 15843671 10.1056/NEJMra043430 1:CAS:528: DC%2BD2MXjsFCltrc%3D (Pubitemid 40530235)
10. R Kleemann S Zadelaar T Kooistra 2008 Cytokines and atherosclerosis: a comprehensive review of studies in mice Cardiovasc Res 79 360 376 10.1093/cvr/cvn120 18487233 10.1093/cvr/cvn120 1:CAS:528:DC%2BD1cXptlykt7s%3D
11. M Baggiolini B Dewald B Moser 1994 Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines Adv Immunol 55 97 179 8304236 10.1016/S0065-2776(08)60509-X 1:CAS:528:DyaK2cXktlamtr8%3D
12. RE Gerszten EA Garcia-Zepeda Y-C Lim M Yoshidak HA Ding MA Gimbrone Jr AD Luster FW Luscinskas A Rosenzweig 1999 MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions Nature 398 718 723 10.1038/19546 10227295 10.1038/19546 1:CAS:528:DyaK1MXivVegur8%3D (Pubitemid 29197651)
13. VK Somers DP White R Amin WT Abraham F Costa A Culebras S Daniels JS Floras CE Hunt LJ Olson TG Pickering R Russell M Woo T Young American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology American Heart Association Stroke Council; American Heart Association Council on Cardiovascular Nursing American College of Cardiology Foundation 2008 Sleep apnea and cardiovascular disease. An american heart association/american college of cardiology foundation scientific statement from the American heart association council for high blood pressure research professional education committee, council on clinical cardiology, stroke council, and council on cardiovascular nursing council Circulation 118 1080 1111 10.1161/CIRCULATIONAHA.107.189420 18725495 10.1161/CIRCULATIONAHA.107. 189420
14. PM Ridker E Danielson FA Fonseca J Genest AM Gotto Jr JJ Kastelein W Koenig P Libby AJ Lorenzatti JG MacFadyen BG Nordestgaard J Shepherd JT Willerson RJ Glynn JUPITER Study Group 2008 Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein N Engl J Med 359 2195 2207 10.1056/NEJMoa0807646 18997196 10.1056/NEJMoa0807646 1:CAS:528: DC%2BD1cXhtl2gurnL
15. S Kinlay GG Schwartz AG Olsson N Rifai SJ Leslie WJ Sasiela M Szarek P Libby P Ganz Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering Study Investigators 2003 High-dose atorvastatin enhances the decline in inflammatory markers in patients with acute coronary syndromes in the MIRACL study Circulation 108 1560 1566 10.1161/01.CIR.0000091404.09558.AF 12975259 10.1161/01.CIR.0000091404.09558.AF 1:CAS:528:DC%2BD3sXnsVKrs7c%3D (Pubitemid 37187781)
16. K Yasunari K Maeda M Nakamura T Watanabe J Yoshikawa A Asada 2004 Effects of carvedilol on oxidative stress in polymorphonuclear and mononuclear cells in patients with essential hypertension Am J Med 116 460 465 10.1016/j.amjmed. 2003.10.029 15047035 10.1016/j.amjmed.2003.10.029 1:CAS:528:DC%2BD2cXisVemsro%3D (Pubitemid 38388615)
17. K Yasunari K Maeda M Nakamura T Watanabe J Yoshikawa 2005 Benidipine, a long-acting calcium channel blocker, inhibits oxidative stress in polymorphonuclear cells in patients with essential hypertension Hypertens Res 28 107 112 10.1291/hypres.28.107 16025736 10.1291/hypres.28.107 1:CAS:528:DC%2BD2MXktlOrt78%3D (Pubitemid 40663060)
18. I Seres G Fóris D Páll B Kosztáczky G Paragh Jr Z Varga G Paragh 2005 Angiotensin II-induced oxidative burst is fluvastatin sensitive in neutrophils of patients with hypercholesterolemia Metabolism 54 1147 1154 10.1016/j.metabol.2005.03.021 16125525 10.1016/j.metabol.2005.03.021 1:CAS:528:DC%2BD2MXpsVWkurk%3D (Pubitemid 41206874)
19. S Sela R Shurtz-Swirski M Cohen-Mazor R Mazor J Chezar G Shapiro K Hassan G Shkolnik R Geron B Kristal 2005 Primed peripheral polymorphonuclear leukocytes: a culprit underlying chronic low-grade inflammation and systemic oxidative stress in chronic kidney disease J Am Soc Nephrol 16 2431 2438 10.1681/ASN.2004110929 15987755 10.1681/ASN.2004110929 1:CAS:528: DC%2BD2MXovVOku7g%3D (Pubitemid 41725061)
20. R Shurtz-Swirski S Sela G Shapiro L Nasser SM Shasha B Kristal 2001 Involvement of polymorphonuclear leukocytes in oxidative stress and inflammation in type 2 diabetes Diabetes Care 24 104 110 10.2337/diacare.24.1.104 11194213 10.2337/diacare.24.1.104 1:STN:280:DC%2BD3MzgtVansQ%3D%3D (Pubitemid 32104229)
21. R Sugano H Matsuoka N Haramaki H Umei E Murase K Fukami S Iida H Ikeda T Imaizumi 2005 Polymorphonuclear leukocytes may impair endothelial function. Results of crossover randomized study of lipid-lowering therapies Arterioscler Thromb Vasc Biol 25 1262 1267 10.1161/01.ATV.0000163842.91226.ba 15790932 10.1161/01.ATV.0000163842.91226.ba 1:CAS:528:DC%2BD2MXksVWqsbk%3D (Pubitemid 40776619)
22. L Guasti F Marino M Cosentino M Cimpanelli RC Maio C Klersy C Crespi D Restelli C Simoni I Franzetti G Gaudio P Marnini AM Grandi S Lecchini A Venco 2006 Simvastatin treatment modifies polymorphonuclear leukocyte function in high-risk individuals: a longitudinal study J Hypertens 24 2423 2430 10.1097/01.hjh.0000251903.62804.77 17082725 10.1097/01.hjh.0000251903.62804.77 1:CAS:528:DC%2BD28XhtFGgsbrE (Pubitemid 44684691)
23. F Marino L Guasti M Cosentino E Rasini M Ferrari RC Maio A Loraschi MG Cimpanelli L Schembri M Legnaro E Molteni C Crespi F Crema A Venco S Lecchini 2008 Simvastatin treatment in subjects at high cardiovascular risk modulates AT1R expression on circulating monocytes and T lymphocytes J Hypertens 26 1147 1155 10.1097/HJH.0b013e3282f97dde 18475152 10.1097/HJH.0b013e3282f97dde 1:CAS:528:DC%2BD1cXlslGlsLs%3D (Pubitemid 351670506)
24. L Guasti F Marino M Cosentino E Rasini M Ferrari L Castiglioni C Klersy G Gaudio AM Grandi S Lecchini A Venco 2008 Prolonged statin-associated reduction in neutrophil reactive oxygen species and angiotensin II type 1 receptor expression: 1-year follow-up Eur Heart J 29 1118 1126 10.1093/eurheartj/ehn138 18390537 10.1093/eurheartj/ehn138 1:CAS:528:DC%2BD1cXmvV2ks7w%3D (Pubitemid 351844894)
25. AV Chobanian GL Bakris HR Black WC Cushman LA Green JL Izzo Jr DW Jones BJ Materson S Oparil JT Wright Jr EJ Roccella National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure National High Blood Pressure Education Program Coordinating Committee 2003 The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure JAMA 289 2560 2572 10.1001/jama.289.19.2560 12748199 10.1001/jama.289.19.2560 1:CAS:528:DC%2BD3sXjvFCqtrk%3D (Pubitemid 37430158)
26. American Diabetes Association 2008 Diagnosis and classification of diabetes mellitus Diabetes Care 31 Suppl 1 S55 S60 10.2337/dc08-S055 10.2337/dc08-S055 (Pubitemid 351520689)
27. SM Grundy HB Brewer Jr JI Cleeman SC Smith Jr C Lenfant 2004 American Heart Association; National Heart, Lung, and Blood Institute. Definition of metabolic syndrome. Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on Scientific Issues Related to Definition Circulation 109 433 438 10.1161/01.CIR.0000111245.75752.C6 14744958 10.1161/01.CIR.0000111245.75752.C6 (Pubitemid 38133916)
28. P Poirier TD Giles GA Bray Y Hong JS Stern FX Pi-Sunyer RH Eckel American Heart Association; Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism 2006 Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American heart association scientific statement on obesity and heart disease from the obesity committee of the council on nutrition, physical activity, and metabolism Circulation 113 898 918 10.1161/CIRCULATIONAHA.106.171016 16380542 10.1161/CIRCULATIONAHA.106.171016
29. I Alam K Lewis JW Stephens JN Baxter 2006 Obesity, metabolic syndrome and sleep apnea: all pro-inflammatory states Obes Rev 8 119 127 10.1111/j.1467-789X.2006.00269.x 10.1111/j.1467-789X.2006.00269.x
30. J Jacobi S Sela HI Cohen J Chezar B Kristal 2006 Priming of polymorphonuclear leukocytes: a culprit in initiation of endothelial cell injury Am J Physiol Heart Circ Physiol 290 H2051 H2058 10.1152/ajpheart.01040.2005 16387791 10.1152/ajpheart.01040.2005 1:CAS:528:DC%2BD28XkvFSmtrc%3D
31. P Libby PM Ridker A Maseri 2002 Inflammation and atherosclerosis Circulation 105 1135 1143 10.1161/hc0902.104353 11877368 10.1161/hc0902.104353 1:CAS:528:DC%2BD38XislWhu7k%3D (Pubitemid 34212626)
32. G Tripepi F Mallamaci C Zoccali 2005 Inflammation markers, adhesion molecules, and all-cause and cardiovascular mortality in patients with ESRD: searching for the best risk marker by multivariate modelling J Am Soc Nephrol 16 Suppl 1 S83 S88 10.1681/ASN.2004110972 15938042 10.1681/ASN.2004110972 1:CAS:528:DC%2BD2MXivVOmtLw%3D (Pubitemid 41725091)
33. T Yokoe K Minoguchi H Matsuo N Oda H Minoguchi G Yoshino T Hirano M Adachi 2003 Elevated levels of c-reactive protein and interleukin-6 in patients with obstructive sleep apnoea syndrome are decreased by nasal continuous positive airway pressure Circulation 107 1129 1134 10.1161/01.CIR.0000052627. 99976.18 12615790 10.1161/01.CIR.0000052627.99976.18 1:CAS:528: DC%2BD3sXhsVWru7g%3D (Pubitemid 36297204)
34. S Ryan CT Taylor WT McNicholas 2006 Predictors of elevated nuclear factor-KB-dependent genes in obstructive sleep apnea syndrome Am J Respir Crit Care Med 174 824 830 10.1164/rccm.200601-066OC 16840748 10.1164/rccm.200601- 066OC 1:CAS:528:DC%2BD28XhtFams7jL (Pubitemid 44511665)
35. A Alberti P Sarchielli E Gallinella A Floridi A Floridi G Mazzotta V Gallai 2003 Plasma cytokine levels in patients with obstructive sleep apnea syndrome: a preliminary study J Sleep Res 12 305 311 10.1111/j.1365-2869.2003. 00361.x 14633242 10.1111/j.1365-2869.2003.00361.x (Pubitemid 38010437)
36. TU Ciftci O Kokturk N Bukan A Bilgihan 2004 The relationship between serum cytokine levels with obesity and obstructive sleep apnea syndrome Cytokine 28 87 91 10.1016/j.cyto.2004.07.003 15381186 10.1016/j.cyto.2004.07.003 1:CAS:528:DC%2BD2cXnslKktrc%3D (Pubitemid 39302489)
37. AN Vgontzas DA Papanicolaou EO Bixler A Kales K Tyson GP Chrousos 1997 Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity J Clin Endocrinol Metab 82 1313 1316 0021-972X/97/03.00/0 9141509 10.1210/jc.82.5.1313 1:CAS:528:DyaK2sXjtVGmtLw%3D (Pubitemid 27200394)
38. CL Phillips Q Yang A Williams M Roth BJ Yee JA Hedner N Berend RR Grunstein 2007 The effect of short-term withdrawal from continuous positive airway pressure therapy on sympathetic activity and markers of vascular inflammation in subjects with obstructive sleep apnoea J Sleep Res 16 217 225 10.1111/j.1365-2869.2007.00589.x 17542952 10.1111/j.1365-2869.2007.00589.x (Pubitemid 46850092)
39. H Liu J Liu S Xiong G Shen Z Zhang Y Xu 2000 The change of interleukin-6 and tumor necrosis factor in patients with obstructive sleep apnea syndrome J Tongji Med Univ 20 200 202 11215046 10.1007/BF02886988 1:CAS:528: DC%2BD3cXovFyqu70%3D (Pubitemid 33210383)
40. Z Dorkova D Petrasova A Molcanyiova M Popovnakova R Tkacova 2008 Effects of continuous positive airway pressure on cardiovascular risk profile in patients with severe obstructive sleep apnea and metabolic syndrome Chest 134 686 692 10.1378/chest.08-0556 18625666 10.1378/chest.08-0556 1:CAS:528:DC%2BD1cXhtlaitrnI
41. K Minoguchi T Tazaki T Yokoe H Minoguchi Y Watanabe M Yamamoto M Adachi 2004 Elevated production of tumor necrosis factor α by monocytes in patients with obstructive sleep apnea syndrome Chest 126 1473 1479 10.1378/chest.126.5.1473 15539715 10.1378/chest.126.5.1473 1:CAS:528: DC%2BD2cXhtFSgur7N (Pubitemid 39525019)
42. KM Pou JM Massaro U Hoffmann RS Vasan P Maurovich-Horvat MG Larson JF Keaney Jr JB Meigs I Lipinska S Kathiresan JM Murabito CJ O'Donnell EJ Benjamin CS Fox 2007 Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart Study Circulation 116 1234 1241 10.1161/CIRCULATIONAHA.107. 710509 17709633 10.1161/CIRCULATIONAHA.107.710509 1:CAS:528:DC%2BD2sXpvFWksbk%3D (Pubitemid 47517534)
43. MA Arias F García-Río A Alonso-Fernández A Hernanz R Hidalgo V Martínez-Mateo S Bartolomé L Rodríguez-Padial 2008 CPAP decreases plasma levels of soluble tumour necrosis factor-alpha receptor 1 in obstructive sleep apnoea Eur Respir J 32 1009 1015 10.1183/09031936.00007008 18508832 10.1183/09031936.00007008 1:CAS:528:DC%2BD1cXht1KqsbjF
44. AK Htoo H Greenberg S Tongia G Chen T Henderson D Wilson 2006 Liu SF (2006) Activation of nuclear factor kappaB in obstructive sleep apnea: a pathway leading to systemic inflammation Sleep Breath 10 43 50 10.1007/s11325-005-0046- 6 16491391 10.1007/s11325-005-0046-6 (Pubitemid 44193436)
45. S Jelic M Padeletti SM Kawut C Higgins SM Canfield D Onat PC Colombo RC Basner P Factor TH LeJemtel 2008 Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea Circulation 117 2270 2278 10.1161/CIRCULATIONAHA.107.741512 18413499 10.1161/CIRCULATIONAHA.107. 741512 1:CAS:528:DC%2BD1cXkvFSjtLw%3D
46. M de la Peña A Barceló F Barbe J Piérola J Pons E Rimbau O Ayllón AG Agustí 2008 Endothelial function and circulating endothelial progenitor cells in patients with sleep apnea syndrome Respiration 76 28 32 10.1159/000109643 17921670 10.1159/000109643 (Pubitemid 351914136)
47. E Ohga T Tomita H Wada H Yamamoto T Nagase Y Ouchi 2003 Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1 J Appl Physiol 94 179 184 10.1152/japplphysiol.00177.2002 12391099 1:CAS:528: DC%2BD3sXltFGruw%3D%3D (Pubitemid 36014310)
48. M Kohler L Ayers JC Pepperell KL Packwood B Ferry N Crosthwaite S Craig MM Siccoli RJ Davies JR Stradling 2009 Effects of continuous positive airway pressure on systemic inflammation in patients with moderate to severe obstructive sleep apnoea: a randomised controlled trial Thorax 64 67 73 10.1136/thx.2008.097931 18786982 10.1136/thx.2008.097931 1:STN:280: DC%2BD1M%2FgtFCisg%3D%3D