-
1
-
-
30444437486
-
Treatment of acute lymphoblastic leukemia
-
Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. N Engl J Med 2006;354:166-78.
-
(2006)
N Engl J Med
, vol.354
, pp. 166-178
-
-
Pui, C.H.1
Evans, W.E.2
-
2
-
-
8944251627
-
Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL): A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM 90 and CoALL-05-92
-
Schlieben S, Borkhardt A, Reinisch I, Ritterbach J, Janssen JW, Ratei R, et al. Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL): A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM 90 and CoALL-05-92. Leukemia 1996;10:957-63.
-
(1996)
Leukemia
, vol.10
, pp. 957-963
-
-
Schlieben, S.1
Borkhardt, A.2
Reinisch, I.3
Ritterbach, J.4
Janssen, J.W.5
Ratei, R.6
-
3
-
-
0029816460
-
The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
-
Melo JV. The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype. Blood 1996;88:2375-84.
-
(1996)
Blood
, vol.88
, pp. 2375-2384
-
-
Melo, J.V.1
-
4
-
-
79953769788
-
Philadelphia chromosomepositive acute lymphoblastic leukemia: Current treatment and future perspective
-
Lee HJ, Thompson JE, Wang ES, Wetzier M. Philadelphia chromosomepositive acute lymphoblastic leukemia: current treatment and future perspective. Cancer 2011;117:1583-94.
-
(2011)
Cancer
, vol.117
, pp. 1583-1594
-
-
Lee, H.J.1
Thompson, J.E.2
Wang, E.S.3
Wetzier, M.4
-
5
-
-
66549084080
-
Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: Results from the international ALL Trial MRC UKALLXII/ECOG2993
-
Fielding AK, Rowe JM, Richards SM, Buck G, Moorman AV, Durrant IJ, et al. Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the international ALL Trial MRC UKALLXII/ECOG2993. Blood 2009;113:4489-96.
-
(2009)
Blood
, vol.113
, pp. 4489-4496
-
-
Fielding, A.K.1
Rowe, J.M.2
Richards, S.M.3
Buck, G.4
Moorman, A.V.5
Durrant, I.J.6
-
6
-
-
0034611661
-
Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Aricò M, Valsecchi MG, Camitta B, Schrappe M, Chessells J, Baruchel A, et al. Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. N Engl J Med 2000;342:998-1006.
-
(2000)
N Engl J Med
, vol.342
, pp. 998-1006
-
-
Aricò, M.1
Valsecchi, M.G.2
Camitta, B.3
Schrappe, M.4
Chessells, J.5
Baruchel, A.6
-
7
-
-
78149276142
-
Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005
-
Aricò M, Schrappe M, Hunger SP, Carroll WL, Conter V, Galimberti S, et al. Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005. J Clin Oncol 2010;28:4755-61.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4755-4761
-
-
Aricò, M.1
Schrappe, M.2
Hunger, S.P.3
Carroll, W.L.4
Conter, V.5
Galimberti, S.6
-
8
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, Ohno S, Seqal GM, Fanning S, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996;2:561-6.
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
Ohno, S.4
Seqal, G.M.5
Fanning, S.6
-
9
-
-
0035810142
-
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
-
Druker BJ, Sawyers CL, Kantarjian H, Resta DJ, Reese SF, Ford JM, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001;344:1038-42.
-
(2001)
N Engl J Med
, vol.344
, pp. 1038-1042
-
-
Druker, B.J.1
Sawyers, C.L.2
Kantarjian, H.3
Resta, D.J.4
Reese, S.F.5
Ford, J.M.6
-
10
-
-
20844452050
-
Imatinib mesylate (STI571) for treatment of children with Philadelphia chromosome-positive leukemia: Results from a Children's Oncology Group phase 1 study
-
Champagne MA, Capdeville R, Krailo M, Peng B, Rosamilia M, Therrien M, et al. Imatinib mesylate (STI571) for treatment of children with Philadelphia chromosome-positive leukemia: results from a Children's Oncology Group phase 1 study. Blood 2004;104:2655-60.
-
(2004)
Blood
, vol.104
, pp. 2655-2660
-
-
Champagne, M.A.1
Capdeville, R.2
Krailo, M.3
Peng, B.4
Rosamilia, M.5
Therrien, M.6
-
11
-
-
70449711127
-
Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: A children's oncology group study
-
Schultz KR, Bowman WP, Aledo A, Slayton WB, Sather H, Devidas M, et al. Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study. J Clin Oncol 2009;27:5175-81.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5175-5181
-
-
Schultz, K.R.1
Bowman, W.P.2
Aledo, A.3
Slayton, W.B.4
Sather, H.5
Devidas, M.6
-
12
-
-
73949101817
-
Current treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Fielding AK. Current treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia. Haematologica 2010;95:8-12.
-
(2010)
Haematologica
, vol.95
, pp. 8-12
-
-
Fielding, A.K.1
-
13
-
-
77953790762
-
Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl) ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl) phenyl}benzamide(AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant
-
Huang WS, Metcalf CA, Sundaramoorthi R, Wang Y, Zou D, Thomas RM, et al. Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl) ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl) phenyl}benzamide(AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase including the T315I gatekeeper mutant. J Med Chem 2010;53:4701-19.
-
(2010)
J Med Chem
, vol.53
, pp. 4701-4719
-
-
Huang, W.S.1
Metcalf, C.A.2
Sundaramoorthi, R.3
Wang, Y.4
Zou, D.5
Thomas, R.M.6
-
14
-
-
21144451094
-
In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
-
O'Hare T, Walters DK, Stoffregen EP, Jia T, Manley PW, Mestan J, et al. In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res 2005;65:4500-5.
-
(2005)
Cancer Res
, vol.65
, pp. 4500-4505
-
-
O'Hare, T.1
Walters, D.K.2
Stoffregen, E.P.3
Jia, T.4
Manley, P.W.5
Mestan, J.6
-
15
-
-
51649111035
-
Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosomepositive leukemia
-
Porkka K, Koskenvesa P, Lundan T, Rimpilainen J, Mustjoki S, Smykla R, et al. Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosomepositive leukemia. Blood 2008;112:1005-12.
-
(2008)
Blood
, vol.112
, pp. 1005-1012
-
-
Porkka, K.1
Koskenvesa, P.2
Lundan, T.3
Rimpilainen, J.4
Mustjoki, S.5
Smykla, R.6
-
16
-
-
78649505429
-
Philadelphia chromosome-positive Acute Lymphoblastic Leukemia in Children: New and Emerging Treatment Options
-
Schultz KR, Prestidge T, Camitta B. Philadelphia chromosome-positive Acute Lymphoblastic Leukemia in Children: New and Emerging Treatment Options. Expert Rev Hematol 2010;3:731-42.
-
(2010)
Expert Rev Hematol
, vol.3
, pp. 731-742
-
-
Schultz, K.R.1
Prestidge, T.2
Camitta, B.3
-
17
-
-
13844251975
-
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
-
Weisberg E, Manley PW, Breitenstein W, Brüggen J, Cowan-Jacob SW, Ray A, et al. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell 2005;7:129-41.
-
(2005)
Cancer Cell
, vol.7
, pp. 129-141
-
-
Weisberg, E.1
Manley, P.W.2
Breitenstein, W.3
Brüggen, J.4
Cowan-Jacob, S.W.5
Ray, A.6
-
18
-
-
33745086350
-
Nilotinib in imatinib-resistant CML and Philadelphia chromosome positive ALL
-
Kantarjian H, Giles F, Wunderle L, Bhalla K, O'Brien S, Wassmann B, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome positive ALL. N Engl J Med 2006;354:2542-51.
-
(2006)
N Engl J Med
, vol.354
, pp. 2542-2551
-
-
Kantarjian, H.1
Giles, F.2
Wunderle, L.3
Bhalla, K.4
O'Brien, S.5
Wassmann, B.6
-
19
-
-
43549121556
-
Nilotinib in patients with relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who are resistant or intolerant to imatinib
-
Ottmann OG, Larson RA, Kantarjian HM, Coutre PI, Baccarani M, Haque A, et al. Nilotinib in patients with relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) who are resistant or intolerant to imatinib. Blood 2007;110, 2815a.
-
(2007)
Blood
, vol.110
, pp. 2815
-
-
Ottmann, O.G.1
Larson, R.A.2
Kantarjian, H.M.3
Coutre, P.I.4
Baccarani, M.5
Haque, A.6
-
20
-
-
68049137764
-
Longitudinal growth retardation in a prepubertal girl with chronic myeloid leukemia on longterm treatment with imatinib
-
Schmid H, Jaeger BA, Lohse J, Suttorp M. Longitudinal growth retardation in a prepubertal girl with chronic myeloid leukemia on longterm treatment with imatinib. Haematologica 2009;94:1177-9.
-
(2009)
Haematologica
, vol.94
, pp. 1177-1179
-
-
Schmid, H.1
Jaeger, B.A.2
Lohse, J.3
Suttorp, M.4
-
21
-
-
70450277310
-
Imatinib mesylate causes growth plate closure in vivo
-
Vandyke K, Dewar AL, Fitter S, Menicanin D, To LB, Hughes TP, et al. Imatinib mesylate causes growth plate closure in vivo. Leukemia 2009;23:2155-9.
-
(2009)
Leukemia
, vol.23
, pp. 2155-2159
-
-
Vandyke, K.1
Dewar, A.L.2
Fitter, S.3
Menicanin, D.4
To, L.B.5
Hughes, T.P.6
-
22
-
-
20244387988
-
Significant reduction of the hybrid BCR/ABL transcripts after induction and consolidation therapy is a powerful predictor of treatment response in adult Philadelphia-positive acute lymphoblastic leukemia
-
Pane F, Cimino G, Izzo B, Camera A, Vitale A, Quintarelli C, et al. Significant reduction of the hybrid BCR/ABL transcripts after induction and consolidation therapy is a powerful predictor of treatment response in adult Philadelphia-positive acute lymphoblastic leukemia. Leukemia 2005;19: 628-35.
-
(2005)
Leukemia
, vol.19
, pp. 628-635
-
-
Pane, F.1
Cimino, G.2
Izzo, B.3
Camera, A.4
Vitale, A.5
Quintarelli, C.6
-
23
-
-
40849147389
-
Karyotype at diagnosis is the major prognostic factor predicting relapsefree survival for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy
-
Yanada M, Takeuchi J, Sugiura I, Akiyama H, Usui N, Yagasaki F, et al. Karyotype at diagnosis is the major prognostic factor predicting relapsefree survival for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with imatinib-combined chemotherapy. Haematologica 2008;93:287-90.
-
(2008)
Haematologica
, vol.93
, pp. 287-290
-
-
Yanada, M.1
Takeuchi, J.2
Sugiura, I.3
Akiyama, H.4
Usui, N.5
Yagasaki, F.6
-
24
-
-
84895916015
-
Secondary chromosomal abnormalities appear to be less prognostic for children with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) treated with intensified Imatinib and chemotherapy: Results of the Children's Oncology Group (COG) study AALL0031
-
Carroll AJ, Heerema NA, Devidas M, Bowman WP, Wang C, Trigg M, et al. Secondary chromosomal abnormalities appear to be less prognostic for children with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) treated with intensified Imatinib and chemotherapy: Results of the Children's Oncology Group (COG) study AALL0031. Blood 2009;114:2606a.
-
(2009)
Blood
, vol.114
, pp. 2606
-
-
Carroll, A.J.1
Heerema, N.A.2
Devidas, M.3
Bowman, W.P.4
Wang, C.5
Trigg, M.6
|