메뉴 건너뛰기




Volumn 48, Issue 4, 2010, Pages 555-563

Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in normal and pathological human oral mucosa

Author keywords

Carcinoma; Cyclooxigenases; Dysplasia; Human oral mucosa; Hyperplasia

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; MESSENGER RNA;

EID: 79958044103     PISSN: 02398508     EISSN: 18975631     Source Type: Journal    
DOI: 10.2478/v10042-010-0066-3     Document Type: Article
Times cited : (18)

References (46)
  • 1
    • 0027141004 scopus 로고
    • Cloning two isoforms of rat cyclooxygenase: Differential regulation of their expression
    • Feng L, Sun W, Xia Y, et al. Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression. Arch Biochem Biophys. 1993;307(2):361-8.
    • (1993) Arch Biochem Biophys , vol.307 , Issue.2 , pp. 361-368
    • Feng, L.1    Sun, W.2    Xia, Y.3
  • 2
    • 0026730021 scopus 로고
    • Human cyclooxygenase-2 cDNA
    • Hla T and Neilson K. Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci U S A. 1992;89(16):7384-8.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.16 , pp. 7384-7388
    • Hla, T.1    Neilson, K.2
  • 3
    • 0027469850 scopus 로고
    • Expression of the protein product of the prostaglandin synthase- 2/ gene in mitogen-stimulated Swiss 3T3 cells
    • Kujubu DA, Reddy ST, Fletcher BS and Herschman HR. Expression of the protein product of the prostaglandin synthase- 2/ gene in mitogen-stimulated Swiss 3T3 cells. J Biol Chem. 1993;268:5425-30.
    • (1993) J Biol Chem , vol.268 , pp. 5425-5430
    • Kujubu, D.A.1    Reddy, S.T.2    Fletcher, B.S.3    Herschman, H.R.4
  • 4
    • 18144438592 scopus 로고    scopus 로고
    • Up-regulation of cyclooxygenase-2 in squamous carcinogenesis of the esophagus
    • Shamma A, Yamamoto H, Doki Y et al. Up-regulation of cyclooxygenase-2 in squamous carcinogenesis of the esophagus. Clin Cancer Res. 2000;6(4):1229-38.
    • (2000) Clin Cancer Res , vol.6 , Issue.4 , pp. 1229-1238
    • Shamma, A.1    Yamamoto, H.2    Doki, Y.3
  • 6
    • 14644417232 scopus 로고    scopus 로고
    • Cyclo-oxigenase-1 and- 2 expression in human oral mucosa, dysplasias and squamous cell carcinomas and their pathological significance
    • Shibata M, Kodani I, Osaki M et al. Cyclo-oxigenase-1 and- 2 expression in human oral mucosa, dysplasias and squamous cell carcinomas and their pathological significance. Oral Oncology. 2005;41:304-312.
    • (2005) Oral Oncology , vol.41 , pp. 304-312
    • Shibata, M.1    Kodani, I.2    Osaki, M.3
  • 7
    • 34547135170 scopus 로고    scopus 로고
    • Cyclooxygenase isozymes in oral squamous cell carcinoma:A real-time RT-PCR study with clinic pathological correlations
    • Pannone G, Sanguedolce F, De Maria S, Farina E, Lo Muzio L, Serpico R, et al. Cyclooxygenase isozymes in oral squamous cell carcinoma:a real-time RT-PCR study with clinic pathological correlations. Int J Immunopathol Pharmacol. 2007;20(2):317-24.
    • (2007) Int J Immunopathol Pharmacol , vol.20 , Issue.2 , pp. 317-324
    • Pannone, G.1    Sanguedolce, F.2    de Maria, S.3    Farina, E.4    lo Muzio, L.5    Serpico, R.6
  • 8
    • 45749145820 scopus 로고    scopus 로고
    • Expression of cytosolic phospholipase A2 and cyclooxygenase 2 and their significance in human oral mucosae, dysplasias and squamous cell carcinomas
    • Zhang S, Du Y, Tao J, Wu Y, Chen N. Expression of cytosolic phospholipase A2 and cyclooxygenase 2 and their significance in human oral mucosae, dysplasias and squamous cell carcinomas. ORL J Otorhinolaryngol Relat Spec. 2008;70(4): 242-8.
    • (2008) ORL J Otorhinolaryngol Relat Spec , vol.70 , Issue.4 , pp. 242-248
    • Zhang, S.1    Du, Y.2    Tao, J.3    Wu, Y.4    Chen, N.5
  • 9
    • 68049106111 scopus 로고    scopus 로고
    • Expression of pro-inflammatory protein, iNOS, VEGF and COX-2 in oral squamous cell carcinoma (OSCC), relationship with angiogenesis and their clinico-pathological correlation
    • Sappayatosok K, Maneerat Y, Swasdison S, Viriyavejakul P, Dhanuthai K, Zwang J, et al. Expression of pro-inflammatory protein, iNOS, VEGF and COX-2 in oral squamous cell carcinoma (OSCC), relationship with angiogenesis and their clinico-pathological correlation. Med Oral Patol Oral Cir Bucal. 2009;14(7):E319-24.
    • (2009) Med Oral Patol Oral Cir Bucal , vol.14 , Issue.7
    • Sappayatosok, K.1    Maneerat, Y.2    Swasdison, S.3    Viriyavejakul, P.4    Dhanuthai, K.5    Zwang, J.6
  • 10
    • 77649229334 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors
    • McCormick DL, Phillips JM, Horn TL, Johnson WD, Steele VE, Lubet RA. Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors. Cancer Prev Res (Phila Pa). 2010;3(1):73-81.
    • (2010) Cancer Prev Res (Phila Pa) , vol.3 , Issue.1 , pp. 73-81
    • McCormick, D.L.1    Phillips, J.M.2    Horn, T.L.3    Johnson, W.D.4    Steele, V.E.5    Lubet, R.A.6
  • 11
    • 0034994651 scopus 로고    scopus 로고
    • Cyclooxygenase- 2: A novel target for cancer chemotherapy?
    • Dempke W, Rie C, Grothey A and Schmoll HJ. Cyclooxygenase- 2: a novel target for cancer chemotherapy? J Cancer Res Clin Oncol. 2001;127(7):411-7.
    • (2001) J Cancer Res Clin Oncol , vol.127 , Issue.7 , pp. 411-417
    • Dempke, W.1    Rie, C.2    Grothey, A.3    Schmoll, H.J.4
  • 12
    • 34547578958 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer
    • Harris RE. Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer. Subcell Biochem. 2007;42:93-126.
    • (2007) Subcell Biochem , vol.42 , pp. 93-126
    • Harris, R.E.1
  • 13
  • 14
    • 0019986220 scopus 로고
    • Effects of nonsteroidal anti-inflammatory drugs on fatty acid cyclooxygenase and prostaglandin hydroperoxidase activities
    • Mizuno K, Yamamoto S and Lands WE. Effects of nonsteroidal anti-inflammatory drugs on fatty acid cyclooxygenase and prostaglandin hydroperoxidase activities. Prostaglandins. 1982;23:743-57.
    • (1982) Prostaglandins , vol.23 , pp. 743-757
    • Mizuno, K.1    Yamamoto, S.2    Lands, W.E.3
  • 15
    • 1242338040 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 is associated with radioresistance in oral squamous cell carcinoma
    • Terakado N, Shintani S, Yano J et al. Overexpression of cyclooxygenase-2 is associated with radioresistance in oral squamous cell carcinoma. Oral Oncology. 2004;40:383-389.
    • (2004) Oral Oncology , vol.40 , pp. 383-389
    • Terakado, N.1    Shintani, S.2    Yano, J.3
  • 16
    • 33745871231 scopus 로고    scopus 로고
    • Expression of cyclooxygenase- 2 in Gastrointestinal Carcinoid Tumors
    • Mizuno S, Kato K, Hashimoto A et al. Expression of cyclooxygenase- 2 in Gastrointestinal Carcinoid Tumors. J Gastroenterol Hepatol. 2006;21(8):1313-1319.
    • (2006) J Gastroenterol Hepatol , vol.21 , Issue.8 , pp. 1313-1319
    • Mizuno, S.1    Kato, K.2    Hashimoto, A.3
  • 18
    • 48749132331 scopus 로고    scopus 로고
    • Matrix metalloproteinase- 2 matrix metalloproteinase-9 and inducible nitric oxide synthase in oral leukoplakia: Immunohistochemistry and RT-PCR analysis
    • Tortorici S, Mauro A, Burruano F et al. Matrix metalloproteinase- 2 matrix metalloproteinase-9 and inducible nitric oxide synthase in oral leukoplakia: immunohistochemistry and RT-PCR analysis. J Biol Regul Homeost Agents. 2008; 22(2):125-30.
    • (2008) J Biol Regul Homeost Agents , vol.22 , Issue.2 , pp. 125-130
    • Tortorici, S.1    Mauro, A.2    Burruano, F.3
  • 19
    • 74949088915 scopus 로고    scopus 로고
    • Immunohistochemical and transcriptional expression of the matrix metalloproteinases MMP-2 and MMP-9 in normal and pathological human oral mucosa
    • Lipari L, Mauro A, Tortorici S et al. Immunohistochemical and transcriptional expression of the matrix metalloproteinases MMP-2 and MMP-9 in normal and pathological human oral mucosa. J Biol Regul Homeostat Agents. 2009;23(4): 259-67.
    • (2009) J Biol Regul Homeostat Agents , vol.23 , Issue.4 , pp. 259-267
    • Lipari, L.1    Mauro, A.2    Tortorici, S.3
  • 20
    • 13744264176 scopus 로고    scopus 로고
    • COX-2 regulates p53 activity and inhibits DNA damage-induced apoptosis
    • Choi EM, Heo JI, Oh JY et al. COX-2 regulates p53 activity and inhibits DNA damage-induced apoptosis. Biochem Biophys Res Commun. 2005;328(4):1107-12.
    • (2005) Biochem Biophys Res Commun , vol.328 , Issue.4 , pp. 1107-1112
    • Choi, E.M.1    Heo, J.I.2    Oh, J.Y.3
  • 21
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • Wang D and DuBois RN. Prostaglandins and cancer. Gut. 2006;55:115-122.
    • (2006) Gut , vol.55 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2
  • 22
    • 68949117981 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 (COX-2) inhibitors used for preventing or regressing cancer
    • De Souza Pereira R. Selective cyclooxygenase-2 (COX-2) inhibitors used for preventing or regressing cancer. Recent Pat Anticancer Drug Discov. 2009;4(2):157-63.
    • (2009) Recent Pat Anticancer Drug Discov , vol.4 , Issue.2 , pp. 157-163
    • de Souza, P.R.1
  • 23
    • 77749304055 scopus 로고    scopus 로고
    • COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems
    • Katoh H, Hosono K, Ito Y, Suzuki T, Ogawa Y, Kubo H, et al. COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems. Am J Pathol. 2010; 176(3):1469-83.
    • (2010) Am J Pathol , vol.176 , Issue.3 , pp. 1469-1483
    • Katoh, H.1    Hosono, K.2    Ito, Y.3    Suzuki, T.4    Ogawa, Y.5    Kubo, H.6
  • 26
    • 40049087863 scopus 로고    scopus 로고
    • Current status of COX-2 inhibitors
    • Singh P, Mittal A. Current status of COX-2 inhibitors. Mini Rev Med Chem. 2008;8(1):73-90.
    • (2008) Mini Rev Med Chem , vol.8 , Issue.1 , pp. 73-90
    • Singh, P.1    Mittal, A.2
  • 27
    • 60849093525 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) in carcinogenesis and selective COX-2 inhibitors for chemoprevention in gastrointestinal cancers
    • Fujimura T, Ohta T, Oyama K, Miyashita T, Miwa K. Cyclooxygenase-2 (COX-2) in carcinogenesis and selective COX-2 inhibitors for chemoprevention in gastrointestinal cancers. J Gastrointest Cancer. 2007;38(2-4):78-82.
    • (2007) J Gastrointest Cancer , vol.38 , Issue.2-4 , pp. 78-82
    • Fujimura, T.1    Ohta, T.2    Oyama, K.3    Miyashita, T.4    Miwa, K.5
  • 28
    • 36749085341 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2)--a therapeutic target in liver cancer?
    • Breinig M, Schirmacher P, Kern MA. Cyclooxygenase-2 (COX-2)--a therapeutic target in liver cancer? Curr Pharm Des. 2007;13(32):3305-15.
    • (2007) Curr Pharm Des , vol.13 , Issue.32 , pp. 3305-3315
    • Breinig, M.1    Schirmacher, P.2    Kern, M.A.3
  • 29
    • 70449333312 scopus 로고    scopus 로고
    • Multicenter phase II trial of combination therapy with meloxicam, a cox-2 inhibitor, and natural interferon- alpha for metastatic renal cell carcinoma
    • Shinohara N, Kumagai A, Kanagawa K, Maruyama S, Abe T, Sazawa A, et al. Multicenter phase II trial of combination therapy with meloxicam, a cox-2 inhibitor, and natural interferon- alpha for metastatic renal cell carcinoma. Jpn J Clin Oncol. 2009;39(11):720-6.
    • (2009) Jpn J Clin Oncol , vol.39 , Issue.11 , pp. 720-726
    • Shinohara, N.1    Kumagai, A.2    Kanagawa, K.3    Maruyama, S.4    Abe, T.5    Sazawa, A.6
  • 30
    • 62549099627 scopus 로고    scopus 로고
    • Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast
    • Hu M, Peluffo G, Chen H, Gelman R, Schnitt S, Polyak K. Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast. Proc Natl Acad Sci USA. 2009;106(9):3372-7.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.9 , pp. 3372-3377
    • Hu, M.1    Peluffo, G.2    Chen, H.3    Gelman, R.4    Schnitt, S.5    Polyak, K.6
  • 31
    • 64049109107 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung
    • Harris RE. Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung. Inflammopharmacology. 2009;17(2):55-67.
    • (2009) Inflammopharmacology , vol.17 , Issue.2 , pp. 55-67
    • Harris, R.E.1
  • 32
    • 77953016756 scopus 로고    scopus 로고
    • Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2
    • Ohtsu N, Takaoka K, Segawa E, Hashitani S, Noguchi K, Kishimoto H, et al. Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2. Oncol Rep. 2010;24(1):31-6.
    • (2010) Oncol Rep , vol.24 , Issue.1 , pp. 31-36
    • Ohtsu, N.1    Takaoka, K.2    Segawa, E.3    Hashitani, S.4    Noguchi, K.5    Kishimoto, H.6
  • 33
    • 34247875996 scopus 로고    scopus 로고
    • The cyclooxygenase-2 selective inhibitor celecoxib suppresses proliferation and invasiveness in the human oral squamous carcinoma
    • Kwak YE, Jeon NK, Kim J, Lee EJ. The cyclooxygenase-2 selective inhibitor celecoxib suppresses proliferation and invasiveness in the human oral squamous carcinoma. Ann N Y Acad Sci. 2007;1095:99-112.
    • (2007) Ann N Y Acad Sci , vol.1095 , pp. 99-112
    • Kwak, Y.E.1    Jeon, N.K.2    Kim, J.3    Lee, E.J.4
  • 34
    • 67349232801 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via downregulation of matrix metalloproteinase-2 production and activation
    • Kurihara Y, Hatori M, Ando Y, Ito D, Toyoshima T, Tanaka M, et al. Inhibition of cyclooxygenase-2 suppresses the invasiveness of oral squamous cell carcinoma cell lines via downregulation of matrix metalloproteinase-2 production and activation. Clin Exp Metastasis. 2009;26(5):425-32.
    • (2009) Clin Exp Metastasis , vol.26 , Issue.5 , pp. 425-432
    • Kurihara, Y.1    Hatori, M.2    Ando, Y.3    Ito, D.4    Toyoshima, T.5    Tanaka, M.6
  • 35
    • 0034799144 scopus 로고    scopus 로고
    • A selective cyclooxygenase-2 inhibitor, NS-398, enhances the effect of radiation in vitro and in vivo preferentially on the cells that express cyclooxygenase-2
    • Pyo H, Choy H, Amorino GP, Kim JS, Cao Q, Hercules SK, et al. A selective cyclooxygenase-2 inhibitor, NS-398, enhances the effect of radiation in vitro and in vivo preferentially on the cells that express cyclooxygenase-2. Clin Cancer Res. 2001;7:2998-3005.
    • (2001) Clin Cancer Res , vol.7 , pp. 2998-3005
    • Pyo, H.1    Choy, H.2    Amorino, G.P.3    Kim, J.S.4    Cao, Q.5    Hercules, S.K.6
  • 36
    • 0042631411 scopus 로고    scopus 로고
    • Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage nonsmall- cell lung cancer
    • Altorki NK, Keresztes RS, Port JL, Libby DM, Korst RJ, Flieder DB et al. Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage nonsmall- cell lung cancer. J Clin Oncol. 2003;21:2645-2650.
    • (2003) J Clin Oncol , vol.21 , pp. 2645-2650
    • Altorki, N.K.1    Keresztes, R.S.2    Port, J.L.3    Libby, D.M.4    Korst, R.J.5    Flieder, D.B.6
  • 38
    • 74849088932 scopus 로고    scopus 로고
    • Dual EGFR and COX-2 inhibition as a novel approach to targeting head and neck squamous cell carcinoma
    • Kao J, Sikora AT, Fu S. Dual EGFR and COX-2 inhibition as a novel approach to targeting head and neck squamous cell carcinoma. Curr Cancer Drug Targets. 2009;9(8):931-7.
    • (2009) Curr Cancer Drug Targets , vol.9 , Issue.8 , pp. 931-937
    • Kao, J.1    Sikora, A.T.2    Fu, S.3
  • 39
    • 45249106157 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 and DNA topoisomerase II alpha in precancerous and cancerous lesions of the oral mucosa
    • Segawa E, Sakurai K, Kishimoto H, Takaoka K, Noguchi K, Hashitani S, et al. Expression of cyclooxygenase-2 and DNA topoisomerase II alpha in precancerous and cancerous lesions of the oral mucosa. Oral Oncol. 2008;44(7):664-71.
    • (2008) Oral Oncol , vol.44 , Issue.7 , pp. 664-671
    • Segawa, E.1    Sakurai, K.2    Kishimoto, H.3    Takaoka, K.4    Noguchi, K.5    Hashitani, S.6
  • 40
    • 51349084950 scopus 로고    scopus 로고
    • A study of phosphorylated ERK1/2 and COX-2 in early stage (T1-T2) oral squamous cell carcinomas
    • Soland TM, Husvik C, Koppang HS, Boysen M, Sandvik L, Clausen OP, et al. A study of phosphorylated ERK1/2 and COX-2 in early stage (T1-T2) oral squamous cell carcinomas. J Oral Pathol Med. 2008;37(9):535-42.
    • (2008) J Oral Pathol Med , vol.37 , Issue.9 , pp. 535-542
    • Soland, T.M.1    Husvik, C.2    Koppang, H.S.3    Boysen, M.4    Sandvik, L.5    Clausen, O.P.6
  • 41
    • 33845342219 scopus 로고    scopus 로고
    • Cyclooxygenase- 2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion
    • Nystrom ML, McCulloch D, Weinreb PH et al. Cyclooxygenase- 2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion. Cancer Res. 2006; 66(22):10833-42.
    • (2006) Cancer Res , vol.66 , Issue.22 , pp. 10833-10842
    • Nystrom, M.L.1    McCulloch, D.2    Weinreb, P.H.3
  • 42
    • 39749152903 scopus 로고    scopus 로고
    • Prognostic significance of cyclooxygenase-2 and DNA topoisomerase IIalpha expression in oral carcinoma
    • Sakurai K, Urade M, Noguchi K et al. Prognostic significance of cyclooxygenase-2 and DNA topoisomerase IIalpha expression in oral carcinoma. Head Neck. 2007;29(11): 1002-9.
    • (2007) Head Neck , vol.29 , Issue.11 , pp. 1002-1009
    • Sakurai, K.1    Urade, M.2    Noguchi, K.3
  • 43
    • 34247499895 scopus 로고    scopus 로고
    • Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: Association with smokeless tobacco
    • Sawhney M, Rohatgi N, Kaur J et al. Expression of NF-kappaB parallels COX-2 expression in oral precancer and cancer: association with smokeless tobacco. Int J Cancer. 2007;120(12):2545-56.
    • (2007) Int J Cancer , vol.120 , Issue.12 , pp. 2545-2556
    • Sawhney, M.1    Rohatgi, N.2    Kaur, J.3
  • 44
    • 0037652020 scopus 로고    scopus 로고
    • The cyclooxygenase 2-selective inhibitor NS398 inhibits proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis
    • Minter HA, Eveson JW, Huntley S, Elder DJ and Hague A. The cyclooxygenase 2-selective inhibitor NS398 inhibits proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis. Clin Cancer Res. 2003;9(5):1885-97.
    • (2003) Clin Cancer Res , vol.9 , Issue.5 , pp. 1885-1897
    • Minter, H.A.1    Eveson, J.W.2    Huntley, S.3    Elder, D.J.4    Hague, A.5
  • 45
    • 70449709573 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in tumor progression and survival of head and neck squamous cell carcinoma
    • Saba NF, Choi M, Muller S et al. Role of cyclooxygenase-2 in tumor progression and survival of head and neck squamous cell carcinoma. Cancer Prev Res (Phila Pa). 2009; 2(9):823-9.
    • (2009) Cancer Prev Res (Phila Pa) , vol.2 , Issue.9 , pp. 823-829
    • Saba, N.F.1    Choi, M.2    Muller, S.3
  • 46
    • 41249086806 scopus 로고    scopus 로고
    • Overexpression of COX-2 gene in oral cancer is independent of stage of disease and degree of differentiation
    • Pandey M, Prakash O, Santhi WS, Soumithran CS and Pillai RM. Overexpression of COX-2 gene in oral cancer is independent of stage of disease and degree of differentiation. Int J Oral Maxillofac Surg. 2008;37:379-383.
    • (2008) Int J Oral Maxillofac Surg , vol.37 , pp. 379-383
    • Pandey, M.1    Prakash, O.2    Santhi, W.S.3    Soumithran, C.S.4    Pillai, R.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.