T2D-nephropathy linkage within 12q24 locus

Diabetes Research and Clinical Practice

Volumn 92, Issue 3, 2011, Pages

  Gragnoli, Claudia ^a,b,c  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b Temple University   (United States)

^c Bios Biotech Multi Diagnostic Health Center   (Italy)

Author keywords

Diabetic nephropathy; Linkage; PSMD9; SNPs; T2D

Indexed keywords

ADENOSINE; CYTIDINE; GUANOSINE; THYMIDINE;

ARTICLE; CHROMOSOME 12; DIABETIC NEPHROPATHY; DIABETIC RETINOPATHY; GENE LOCUS; GENE MUTATION; GENETIC LINKAGE; GENETIC TRANSCRIPTION; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MICROCIRCULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PHENOTYPE; PREVALENCE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

CHROMOSOMES, HUMAN, PAIR 12; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEASOME ENDOPEPTIDASE COMPLEX;

EID: 79958001279     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2011.02.026     Document Type: Article

References (8)

1. Bowden D.W., Sale M., Howard T.D., Qadri A., Spray B.J., Rothschild C.B., et al. Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy. Diabetes 1997, 46(5):882-886.
2. Ikram M.K., Xueling S., Jensen R.A., Cotch M.F., Hewitt A.W., Ikram M.A., et al. Four novel loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet 2010, 6(10):e1001184.
3. Mahtani M.M., Widen E., Lehto M., Thomas J., McCarthy M., Brayer J., et al. Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families [see comments]. Nat Genet 1996, 14(1):90-94.
4. Gragnoli C., Cronsell J. PSMD9 gene variants within NIDDM2 may rarely contribute to type 2 diabetes. J Cell Physiol 2007, 212(3):568-571.
5. Gragnoli C. PSMD9 gene in the NIDDM2 locus is linked to type 2 diabetes in Italians. J Cell Physiol 2010, 222(2):265-267.
6. Gragnoli C. PSMD9 is linked to MODY3. J Cell Physiol 2010, 223(1):1-5.
7. Thomas M.K.Y.K., Tenser M.S., Wong G.G., Habener J.F. Bridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcription. Mol Cell Biol 1999, 19(12):8492-8504.
8. Abecasis G.R., Cherny S.S., Cookson W.O., Cardon L.R. Merlin-rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 2002, 30(1):97-101.