Simultaneous determination and differentiation of glycidyl esters and 3-monochloropropane-1,2-diol (MCPD) esters in different foodstuffs by GC-MS

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 11, 2011, Pages 6263-6270

  Küsters, Markus ^a   Bimber, Ute ^b   Reeser, Sebastian ^b   Gallitzendörfer, Rainer ^b   Gerhartz, Michael ^b  

^a Central Military Hospital   (Germany)

^b BUNDESWEHRZENTRALKRANKENHAUS KOBLENZ   (Germany)

Author keywords

3 MCPD esters; foodstuff; GC MS; glycidyl esters; oil

Indexed keywords

3-MCPD ESTERS; FOODSTUFF; GC-MS; GLYCIDYL ESTERS; OIL;

BAKERY PRODUCTS; ESTERIFICATION; ESTERS; EXTRACTION; FATTY ACIDS; ISOTOPES;

OILS AND FATS;

3 MONOCHLOROPROPANE 1,2 DIOL; 3-MONOCHLOROPROPANE-1,2-DIOL; DRUG DERIVATIVE; ESTER; GLYCEROL;

ARTICLE; EVALUATION; FOOD ANALYSIS; FOOD CONTAMINATION; MASS FRAGMENTOGRAPHY; METHODOLOGY;

ESTERS; FOOD ANALYSIS; FOOD CONTAMINATION; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLYCEROL;

EID: 79957996832     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf200493b     Document Type: Article

References (18)

1. Hamlet, C. G.; Sadd, P. A.; Crews, C.; Velisek, J.; Baxter, D. E. Occurrence of 3-chloro-propane-1,2-diol (3-MCPD) and related compounds in foods: a review Food Addit. Contam. 2002, 19, 619-631 (Pubitemid 34823521)
2. Zelinkova, Z.; Svejkovska, B.; Velisek, J.; Dolezal, M. Fatty acid esters of 3-chloropropane-1,2-diol in edible oils Food Addit. Contam. 2006, 23, 1290-1298 (Pubitemid 44803819)
3. Küsters, M.; Bimber, U.; Ossenbrüggen, A.; Reeser, S.; Gallitzendörfer, R.; Gerhartz, M. Rapid and simple micromethod for the simultaneous determination of 3-MCPD and 3-MCPD esters in different foodstuffs J. Agric. Food Chem. 2010, 58, 6570-6577
4. Divinova, V.; Svejkovska, B.; Dolezal, M.; Velisek, J. Determination of free and bound 3-chloropropane-1,2-diol by gas chromatography with mass spectrometric detection using deuterated 3-chloropropane-1,2-diol as internal standard Czech. J. Food Sci. 2004, 22, 182-189 (Pubitemid 40008125)
5. Weisshaar, R. Determination of total 3-chloropropane-1,2-diol (3-MCPD) in edible oils by cleavage of MCPD esters with sodium methoxide Eur. J. Lipid Sci. Technol. 2008, 110, 183-186
6. Weisshaar, R. 3-MCPD-esters in edible fats and oils - a new and worldwide problem Eur. J. Lipid Sci. Technol. 2008, 110, 671-672
7. J. Kuhlmann, oral presentation, information session of BLL (German Federation of Food Law and Food Science) and OVID (the association of the oilseed processing industry in Germany) about 3-MCPD- and glycidyl esters in foodstuffs, Berlin, Germany, January 2010; http://www.ovid-verband.de/fileadmin/ user-upload/ovid-verband.de/downloads/SGS-Kuhlmann.pdf.
8. Weisshaar, R.; Perz, R. Fatty acid esters of glycidol in refined fats and oils Eur. J. Lipid Sci. Technol. 2010, 112, 158-165
9. Masukawa, Y.; Shiro, H.; Nakamura, S.; Kondo, N.; Jin, N.; Suzuki, N.; Ooi, N.; Kudo, N. A new analytical method for the quantification of glycidol fatty acid esters in edible oils J. Oleo Sci. 2010, 59, 81-88
10. Svejkovska, B.; Novotny, O.; Divinova, V.; Reblova, Z.; Dolezal, M.; Velisek, J. Esters of 3-chloropropane-1,2-diol in foodstuffs Czech. J. Food Sci. 2004, 22, 190-196 (Pubitemid 40008126)
11. Zelinková, Z.; Doleqal, M.; Velíšek, J. Occurrence of 3-chloropropane-1,2-diol fatty acid esters in infant and baby foods Eur. Food Res. Technol. 2009, 228, 571-578
12. Ketola, M.; Lyytinen, M. R.; Hotokka, M.; Pihlaja, K. Kinetics and mechanisms of dehydrochlorination reactions of simple 1,2-chlorohydrins in aqueous sodium hydroxide solutions Acta Chem. Scand. B 1978, 32, 743-748
13. Stamatova, S. D.; Stawinski, J. Regioselective and stereospecific opening of an oxirane system mediated by trifluoroacetic acid and halide anions. A new direct approach to C3-vicinal halohydrins Tetrahedron Lett. 2007, 48, 1887-1889 (Pubitemid 46241322)
14. Wu, M. H.; Jacobsen, E. N. Asymmetric ring opening of meso epoxides with thiols: enantiomeric enrichment using a bifunctional nucleophile J. Org. Chem. 1998, 63, 5252-5254
15. Colclough, T.; Cunneen, J. I.; Moore, C. G. The aminolysis and esterification of unsymmetrical epoxides Tetrahedron 1961, 15, 187-192
16. Guivisdalsky, P. N.; Bittman, R. Regiospecific opening of glycidyl derivatives mediated by boron trifluoride. Asymmetric synthesis of ether-linked phospholipids J. Org. Chem. 1989, 54, 4637-4642
17. Kežić, S.; Jakaš, I.; Wenker, M. A. M.; Boogaard, P. J.; Monster, A. C.; de Wolff, V. Gas chromatography-electron capture determination of styrene-7,8-oxide enantiomers J. Chromatogr., B 2000, 749, 265-274
18. Baer, I.; de la Calle, B.; Taylor, P. 3-MCPD in food other than soy sauce or hydrolysed vegetable protein (HVP) Anal. Bioanal. Chem. 2010, 396, 443-456