Retinoic acid and α-galactosylceramide differentially regulate B cell activation in vitro and augment antibody production in vivo

Clinical and Vaccine Immunology

Volumn 18, Issue 6, 2011, Pages 1015-1020

  Chen, Qiuyan ^a   Mosovsky, Kara L ^a   Ross, A Catharine ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; FAS LIGAND; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; LYMPHOCYTE ANTIGEN RECEPTOR; RETINOIC ACID; SYNDECAN 1; TETANUS ANTIBODY; TETANUS TOXOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE ACTIVATION; B LYMPHOCYTE DIFFERENTIATION; CELL MATURATION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG POTENTIATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MONOTHERAPY; MOUSE; NONHUMAN; PRIMARY IMMUNE RESPONSE; PRIORITY JOURNAL; SECONDARY IMMUNE RESPONSE; SECRETORY CELL; SINGLE DRUG DOSE; SPLEEN LYMPHOCYTE; TETANUS PROPHYLAXIS; WILD TYPE;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; ANTIGENS, CD1D; ANTITOXINS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; FEMALE; GALACTOSYLCERAMIDES; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; TETANUS TOXOID; TRETINOIN;

EID: 79957991113     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00004-11     Document Type: Article

References (37)

1. Barral, P., et al. 2008. B-cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo. Proc. Natl. Acad. Sci. U. S. A. 105:8345-8350.
2. Borg, N. A., et al. 2007. CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 448:44-49. (Pubitemid 47037002)
3. Brigl, M., and M. B. Brenner. 2010. How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens. Semin. Immunol. 22:79-86.
4. Chen, Q., and A. C. Ross. 2005. Vitamin A and immune function: retinoic acid modulates population dynamics in antigen receptor and CD38-stimulated splenic B cells. Proc. Natl. Acad. Sci. U. S. A. 102:14142-14149.
5. Chen, Q., and A. C. Ross. 2007. Retinoic acid promotes mouse splenic B cell surface IgG expression and maturation stimulated by CD40 and IL-4. Cell. Immunol. 249:37-45.
6. Chen, Q., and A. C. Ross. 2007. Retinoic acid regulates CD1d gene expression at the transcriptional level in human and rodent monocytic cells. Exp. Biol. Med. (Maywood) 232:488-494.
7. Chen, X., et al. 2008. Retinoids accelerate B lineage lymphoid differentiation. J. Immunol. 180:138-145.
8. Devera, T. S., et al. 2010. CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies. Infect. Immun. 78:1610-1617.
9. Devera, T. S., H. B. Shah, G. A. Lang, and M. L. Lang. 2008. Glycolipid-activated NKT cells support the induction of persistent plasma cell responses and antibody titers. Eur. J. Immunol. 38:1001-1011.
10. Dufour, F. D., A. G. Baxter, and P. A. Silveira. 2008. Interactions between B-lymphocytes and type 1 NKT cells in autoimmune diabetes. J. Immunotoxicol. 5:249-257.
11. Ertesvag, A., S. Naderi, and H. K. Blomhoff. 2009. Regulation of B cell proliferation and differentiation by retinoic acid. Semin. Immunol. 21:36-41.
12. Florence, W. C., R. K. Bhat, and S. Joyce. 2008. CD1d-restricted glycolipid antigens: presentation principles, recognition logic, and functional consequences. Expert Rev. Mol. Med. 10:e20.
13. Godfrey, D. I., and M. Kronenberg. 2004. Going both ways: immune regulation via CD1d-dependent NKT cells. J. Clin. Invest. 114:1379-1388.
14. Godfrey, D. I., S. Stankovic, and A. G. Baxter. 2010. Raising the NKT cell family. Nat. Immunol. 11:197-206.
15. Hao, Z., et al. 2008. Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis. Immunity 29:615-627.
16. Lang, G. A., T. S. Devera, and M. L. Lang. 2008. Requirement for CD1d expression by B cells to stimulate NKT cell-enhanced antibody production. Blood 111:2158-2162.
17. Leadbetter, E. A., et al. 2008. NK T cells provide lipid antigen-specific cognate help for B cells. Proc. Natl. Acad. Sci. U. S. A. 105:8339-8344.
18. Lee, Y. S., et al. 2010. An alpha-GalCer analogue with branched acyl chain enhances protective immune responses in a nasal influenza vaccine. Vaccine 29:417-425.
19. Li, D., and X. N. Xu. 2008. NKT cells in HIV-1 infection. Cell Res. 18:817-822.
20. Li, X., et al. 2010. Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant. Proc. Natl. Acad. Sci. U. S. A. 107:13010-13015.
21. Luzina, I. G., et al. 2001. Spontaneous formation of germinal centers in autoimmune mice. J. Leukoc. Biol. 70:578-584.
22. Ma, Y., Q. Chen, and A. C. Ross. 2005. Retinoic acid and polyriboinosinic: polyribocytidylic acid stimulate robust anti-tetanus antibody production while differentially regulating type 1/type 2 cytokines and lymphocyte populations. J. Immunol. 174:7961-7969.
23. Matsuda, J. L., T. Mallevaey, J. Scott-Browne, and L. Gapin. 2008. CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system. Curr. Opin. Immunol. 20:358-368.
24. Maynard, C. L., et al. 2009. Contrasting roles for all-trans retinoic acid in TGF-β-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells. J. Exp. Med. 206:343-357.
25. Mora, J. R., et al. 2006. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science 314:1157-1160. (Pubitemid 44789048)
26. Morikawa, K., and M. Nonaka. 2005. All-trans-retinoic acid accelerates the differentiation of human B lymphocytes maturing into plasma cells. Int. Immunopharmacol. 5:1830-1838.
27. Ortaldo, J. R., et al. 2004. Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides. J. Immunol. 172:943-953. (Pubitemid 38113753)
28. Ross, A. C., Q. Chen, and Y. Ma. 2009. Augmentation of antibody responses by retinoic acid and costimulatory molecules. Semin. Immunol. 21:42-50.
29. Shimizu, K., A. Goto, M. Fukui, M. Taniguchi, and S. Fujii. 2007. Tumor cells loaded with alpha-galactosylceramide induce innate NKT and NK cell-dependent resistance to tumor implantation in mice. J. Immunol. 178:2853-2861. (Pubitemid 46333163)
30. Sigmundsdottir, H., and E. C. Butcher. 2008. Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking. Nat. Immunol. 9:981-987.
31. Sullivan, B. A., et al. 2010. Mechanisms for glycolipid antigen-driven cytokine polarization by Vα14i NKT cells. J. Immunol. 184:141-153.
32. Taniguchi, M., K. Seino, and T. Nakayama. 2003. The NKT cell system: bridging innate and acquired immunity. Nat. Immunol. 4:1164-1165.
33. Venkataswamy, M. M., et al. 2009. Incorporation of NKT cell-activating glycolipids enhances immunogenicity and vaccine efficacy of Mycobacterium bovis bacillus Calmette-Guerin. J. Immunol. 183:1644-1656.
34. Venkataswamy, M. M., and S. A. Porcelli. 2010. Lipid and glycolipid antigens of CD1d-restricted natural killer T cells. Semin. Immunol. 22:68-78.
35. Villamor, E., and W. W. Fawzi. 2005. Effects of vitamin A supplementation on immune responses and correlation with clinical outcomes. Clin. Microbiol. Rev. 18:446-464.
36. Yang, Y., J. W. Tung, E. E. Ghosn, L. A. Herzenberg, and L. A. Herzenberg. 2007. Division and differentiation of natural antibody-producing cells in mouse spleen. Proc. Natl. Acad. Sci. U. S. A. 104:4542-4546.
37. Zhou, D., et al. 2004. Lysosomal glycosphingolipid recognition by NKT cells. Science 306:1786-1789. (Pubitemid 39601398)