Relapse of experimental autoimmune encephalomyelitis after discontinuation of FTY720 (Fingolimod) treatment, but not after combination of FTY720 and pathogenic autoantigen

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 6, 2011, Pages 933-936

  Yoshida, Yuya ^a   Tsuji, Takumi ^a   Fujita, Tetsuro ^b   Kohno, Takeyuki ^a,b  

^a SETSUNAN UNIVERSITY   (Japan)

^b RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT   (Japan)

Author keywords

Experimental autoimmune encephalomyelitis; FTY720; Multiple sclerosis; Relapse

Indexed keywords

CYCLOSPORIN A; FINGOLIMOD; LECTIN; LECTIN 1; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN[35-55]; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEMYELINATION; DISEASE ASSOCIATION; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; RELAPSE; SPINAL CORD; T LYMPHOCYTE;

ANIMALS; AUTOANTIGENS; CYCLOSPORINE; DEMYELINATING DISEASES; DRUG THERAPY, COMBINATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GLYCOPROTEINS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MULTIPLE SCLEROSIS; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PROPYLENE GLYCOLS; RECURRENCE; REMISSION INDUCTION; SPECIFIC PATHOGEN-FREE ORGANISMS; SPHINGOSINE; SPINAL CORD;

EID: 79957974849     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.933     Document Type: Article

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