Bisphosphonate-related subtrochanteric femoral fractures

American Journal Geriatric Pharmacotherapy

Volumn 9, Issue 3, 2011, Pages 194-198

  Gunawardena, Indunil ^a,b   Baxter, Mark ^a   Rasekh, Yama ^a  

^a UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^b Indunil Gunawardena   (United Kingdom)

Author keywords

bisphosphonate; osteoporosis; subtrochanteric fractures

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; GLUCOCORTICOID; VITAMIN D;

AGED; ARTICLE; BONE DENSITY; BONE NAIL; BONE SCINTISCANNING; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CORTICOSTEROID THERAPY; DRUG WITHDRAWAL; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR SUBTROCHANTERIC FRACTURE; FRAGILITY FRACTURE; HIP PAIN; HIP RADIOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LONG TERM CARE; OSTEOPOROSIS; PATIENT MONITORING; PEMPHIGUS VULGARIS; PRIORITY JOURNAL;

AGED; ALENDRONATE; BONE DENSITY CONSERVATION AGENTS; FEMALE; FEMORAL FRACTURES; GREAT BRITAIN; HIP FRACTURES; HUMANS; OSTEOPOROSIS;

EID: 79957973249     PISSN: 15435946     EISSN: 18767761     Source Type: Journal    
DOI: 10.1016/j.amjopharm.2011.02.009     Document Type: Article

References (25)

1. E. Shane Evolving data about subtrochanteric fractures and bisphosphonates N Engl J Med 362 2010 1825 1827
2. R.G. Russell, N.B. Watts, F.H. Ebetino, and M.J. Rogers Mechanisms of action of bisphosphonates: Similarities and differences and their potential influence on clinical efficacy Osteoporos Int 19 2008 733 759
3. N.B. Watts, and D.L. Diab Long-term use of bisphosphonates in osteoporosis J Clin Endocrinol Metab 95 2010 1555 1565
4. J.P. Bilezikian Efficacy of bisphosphonates in reducing fracture risk in postmenopausal osteoporosis Am J Med 122 Suppl 2 2009 S14 S21
5. F. Cosman Treatment of osteoporosis and prevention of new fractures: Role of intravenously administered bisphosphonates Endocr Pract 15 2009 483 493
6. E. Shane, D. Burr, P.R. Ebeling American Society for Bone and Mineral Research Atypical subtrochanteric and diaphyseal femoral fractures: Report of a task force of the American Society for Bone and Mineral Research J Bone Miner Res 25 2010 2267 2294
7. S.K. Goh, K.Y. Yang, and J.S. Koh Subtrochanteric insufficiency fractures in patients on alendronate therapy: A caution J Bone Joint Surg Br 89 2007 349 353 (Pubitemid 46563912)
8. E.B. Kwek, S.K. Goh, and J.S. Koh An emerging pattern of subtrochanteric stress fractures: A long-term complication of alendronate therapy? Injury 39 2008 224 231
9. A.S. Neviaser, J.M. Lane, and B.A. Lenart Low-energy femoral shaft fractures associated with alendronate use J Orthop Trauma 22 2008 346 350 (Pubitemid 351630250)
10. C.V. Odvina, S. Levy, and S. Rao Unusual mid-shaft fractures during long-term bisphosphonate therapy Clin Endocrinol (Oxf) 72 2010 161 168
11. M. Visekruna, D. Wilson, and F.E. McKiernan Severely suppressed bone turnover and atypical skeletal fragility J Clin Endocrinol Metab 93 2008 2948 2952
12. P. Lee, H. van der Wall, and M.J. Seibel Looking beyond low bone mineral density: Multiple insufficiency fractures in a woman with post-menopausal osteoporosis on alendronate therapy J Endocrinol Invest 30 2007 590 597 (Pubitemid 47577812)
13. R.K. Cheung, K.K. Leung, K.C. Lee, and T.C. Chow Sequential non-traumatic femoral shaft fractures in a patient on long-term alendronate Hong Kong Med J 13 2007 485 489 (Pubitemid 351206686)
14. B. Demiralp, S. Ilgan, and A. Ozgur Karacalioglu Bilateral femoral insufficiency fractures treated with inflatable intramedullary nails: A case report Arch Orthop Trauma Surg 127 2007 597 601 (Pubitemid 47226177)
15. M.P. Somford, F.W. Draijer, and B.J. Thomassen Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: Clues to the mechanism of increased bone fragility J Bone Miner Res 24 2009 1736 1740
16. D.A. Kumm, C. Rack, and J. Rutt Subtrochanteric stress fracture of the femur following total knee arthroplasty J Arthroplasty 12 1997 580 583 (Pubitemid 29021316)
17. J.P. Schneider Should bisphosphonates be continued indefinitely? An unusual fracture in a healthy woman on long-term alendronate Geriatrics 61 2006 31 33 (Pubitemid 43134037)
18. A.S. Sayed-Noor, and G.O. Sjdn Case reports: Two femoral insufficiency fractures after long-term alendronate therapy Clin Orthop Relat Res 467 2009 1921 1926
19. G. Husada, K. Libbeerecht, T. Peeters, and J. Populaire Bilateral middiaphyseal femoral stress fractures in the elderly Eur J Trauma 35 2005 68 71 (Pubitemid 40645700)
20. C.V. Odvina, J.E. Zerwekh, and D.S. Rao Severely suppressed bone turnover: A potential complication of alendronate therapy J Clin Endocrinol Metab 90 2005 1294 1301 (Pubitemid 40463979)
21. M. Arlot, P.J. Meunier, and G. Boivin Differential effects of teriparatide and alendronate on bone remodeling in postmenopausal women assessed by histomorphometric parameters J Bone Miner Res 20 2005 1244 1253 (Pubitemid 40863814)
22. J.W. Nieves, and F. Cosman Atypical subtrochanteric and femoral shaft fractures and possible association with bisphosphonates Curr Osteoporos Rep 8 2010 34 39
23. M.P. Somford, F.W. Draijer, and B.J. Thomassen Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: Clues to the mechanism of increased bone fragility J Bone Miner Res 24 2009 1736 1740
24. C.A. Naranjo, U. Busto, and E.M. Sellers A method for estimating the probability of adverse drug reactions Clin Pharmacol Ther 30 1981 239 245 (Pubitemid 12149145)
25. G. Wernecke, S. Namduri, and E.F. DiCarlo Case report of spontaneous, nonspinal fractures in a multiple myeloma patient on long-term pamidronate and zoledronic acid HSS J 4 2008 123 127