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Volumn 8, Issue 1, 2010, Pages 34-39

Atypical Subtrochanteric and Femoral Shaft Fractures and Possible Association with Bisphosphonates

Author keywords

Bisphosphonate; Femoral; Fracture; Osteoporosis; Subtrochanteric

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE;

EID: 77953611357     PISSN: 15441873     EISSN: 15442241     Source Type: Journal    
DOI: 10.1007/s11914-010-0007-2     Document Type: Review
Times cited : (69)

References (30)
  • 1
    • 70449711520 scopus 로고    scopus 로고
    • Treatment of osteoporosis and prevention of new fractures: Role of intravenously administered bisphosphonates
    • Cosman F: Treatment of osteoporosis and prevention of new fractures: role of intravenously administered bisphosphonates. Endocr Pract 2009, 15:483-493.
    • (2009) Endocr Pract , vol.15 , pp. 483-493
    • Cosman, F.1
  • 2
    • 0030871275 scopus 로고    scopus 로고
    • Specific features associated with femoral shaft fractures caused by low-energy trauma
    • Salminen S, Pihlajamaki H, Avikainen V, et al.: Specific features associated with femoral shaft fractures caused by low-energy trauma. J Trauma 1997, 43:117-122.
    • (1997) J Trauma , vol.43 , pp. 117-122
    • Salminen, S.1    Pihlajamaki, H.2    Avikainen, V.3
  • 4
    • 0027535152 scopus 로고
    • Low-energy subtrochanteric fractures in elderly patients: Results of fixation with the sliding screw plate
    • Mullaji AB, Thomas TL: Low-energy subtrochanteric fractures in elderly patients: results of fixation with the sliding screw plate. J Trauma 1993, 34:56-61.
    • (1993) J Trauma , vol.34 , pp. 56-61
    • Mullaji, A.B.1    Thomas, T.L.2
  • 6
    • 62549103755 scopus 로고    scopus 로고
    • Quality of life after a subtrochanteric fracture: A prospective cohort study on 87 elderly patients
    • Ekstrom W, Nemeth G, Samnegard E, et al.: Quality of life after a subtrochanteric fracture: a prospective cohort study on 87 elderly patients. Injury 2009, 40:371-376.
    • (2009) Injury , vol.40 , pp. 371-376
    • Ekstrom, W.1    Nemeth, G.2    Samnegard, E.3
  • 7
    • 34147179587 scopus 로고    scopus 로고
    • Subtrochanteric insufficiency fractures in patients on alendronate therapy: A caution
    • Goh SK, Yang KY, Koh JS, et al.: Subtrochanteric insufficiency fractures in patients on alendronate therapy: a caution. J Bone Joint Surg Br 2007, 89:349-353.
    • (2007) J Bone Joint Surg Br , vol.89 , pp. 349-353
    • Goh, S.K.1    Yang, K.Y.2    Koh, J.S.3
  • 8
    • 38749135807 scopus 로고    scopus 로고
    • An emerging pattern of subtrochanteric stress fractures: A long-term complication of alendronate therapy?
    • Kwek EB, Goh SK, Koh JS, et al.: An emerging pattern of subtrochanteric stress fractures: a long-term complication of alendronate therapy? Injury 2008, 39:224-231.
    • (2008) Injury , vol.39 , pp. 224-231
    • Kwek, E.B.1    Goh, S.K.2    Koh, J.S.3
  • 9
    • 43049129258 scopus 로고    scopus 로고
    • Low-energy femoral shaft fractures associated with alendronate use
    • A total of 70 people (59 women, 11 men), all low-energy subtrochanteric and midshaft femur fractures admitted to a trauma center in New York over 5 years, were reviewed. Of the 25 women on alendronate, 19 were identified as having a specific radiographic pattern (simple transverse fracture with a unicortical beak within a background of cortical hypertrophy). The mean duration of alendronate use was longer in those who had the fracture pattern compared to those without the fracture pattern
    • Neviaser AS, Lane JM, Lenart BA, et al.: Low-energy femoral shaft fractures associated with alendronate use. J Orthop Trauma 2008, 22:346-350. A total of 70 people (59 women, 11 men), all low-energy subtrochanteric and midshaft femur fractures admitted to a trauma center in New York over 5 years, were reviewed. Of the 25 women on alendronate, 19 were identified as having a specific radiographic pattern (simple transverse fracture with a unicortical beak within a background of cortical hypertrophy). The mean duration of alendronate use was longer in those who had the fracture pattern compared to those without the fracture pattern.
    • (2008) J Orthop Trauma , vol.22 , pp. 346-350
    • Neviaser, A.S.1    Lane, J.M.2    Lenart, B.A.3
  • 10
    • 70350193337 scopus 로고    scopus 로고
    • Unusual mid-shaft fractures during long-term bisphosphonate therapy
    • Mar 19 [Epub ahead of print]
    • Odvina CV, Levy S, Rao S, et al.: Unusual mid-shaft fractures during long-term bisphosphonate therapy. Clin Endocrinol (Oxf) 2009 Mar 19 [Epub ahead of print].
    • (2009) Clin Endocrinol (Oxf)
    • Odvina, C.V.1    Levy, S.2    Rao, S.3
  • 11
    • 49249117414 scopus 로고    scopus 로고
    • Severely suppressed bone turnover and atypical skeletal fragility
    • Visekruna M, Wilson D, McKiernan FE: Severely suppressed bone turnover and atypical skeletal fragility. J Clin Endocrinol Metab 2008, 93:2948-2952.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2948-2952
    • Visekruna, M.1    Wilson, D.2    McKiernan, F.E.3
  • 12
    • 35348893265 scopus 로고    scopus 로고
    • Looking beyond low bone mineral density: Multiple insufficiency fractures in a woman with post-menopausal osteoporosis on alendronate therapy
    • Lee P, van der Wall H, Seibel MJ: Looking beyond low bone mineral density: multiple insufficiency fractures in a woman with post-menopausal osteoporosis on alendronate therapy. J Endocrinol Invest 2007, 30:590-597.
    • (2007) J Endocrinol Invest , vol.30 , pp. 590-597
    • Lee, P.1    Van Der Wall, H.2    Seibel, M.J.3
  • 13
    • 38849131454 scopus 로고    scopus 로고
    • Sequential nontraumatic femoral shaft fractures in a patient on long-term alendronate
    • Cheung RK, Leung KK, Lee KC, Chow TC: Sequential nontraumatic femoral shaft fractures in a patient on long-term alendronate. Hong Kong Med J 2007, 13:485-489.
    • (2007) Hong Kong Med J , vol.13 , pp. 485-489
    • Cheung, R.K.1    Leung, K.K.2    Lee, K.C.3    Chow, T.C.4
  • 14
    • 34547727310 scopus 로고    scopus 로고
    • Bilateral femoral insufficiency fractures treated with inflatable intramedullary nails: A case report
    • Demiralp B, Ilgan S, Ozgur Karacalioglu A, et al.: Bilateral femoral insufficiency fractures treated with inflatable intramedullary nails: a case report. Arch Orthop Trauma Surg 2007, 127:597-601.
    • (2007) Arch Orthop Trauma Surg , vol.127 , pp. 597-601
    • Demiralp, B.1    Ilgan, S.2    Ozgur, K.A.3
  • 15
    • 70349907304 scopus 로고    scopus 로고
    • Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: Clues to the mechanism of increased bone fragility
    • Somford MP, Draijer FW, Thomassen BJ, et al.: Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: clues to the mechanism of increased bone fragility. J Bone Miner Res 2009, 24:1736-1740.
    • (2009) J Bone Miner Res , vol.24 , pp. 1736-1740
    • Somford, M.P.1    Draijer, F.W.2    Thomassen, B.J.3
  • 16
    • 33750742219 scopus 로고    scopus 로고
    • Suppressed bone turnover during alendronate therapy for highturnover osteoporosis
    • Armamento-Villareal R, Napoli N, Panwar V, Novack D: Suppressed bone turnover during alendronate therapy for highturnover osteoporosis. N Engl J Med 2006, 355:2048-2050.
    • (2006) N Engl J Med , vol.355 , pp. 2048-2050
    • Armamento-Villareal, R.1    Napoli, N.2    Panwar, V.3    Novack, D.4
  • 17
    • 0031544115 scopus 로고    scopus 로고
    • Subtrochanteric stress fracture of the femur following total knee arthroplasty
    • Kumm DA, Rack C, Rutt J: Subtrochanteric stress fracture of the femur following total knee arthroplasty. J Arthroplasty 1997, 12:580-583.
    • (1997) J Arthroplasty , vol.12 , pp. 580-583
    • Kumm, D.A.1    Rack, C.2    Rutt, J.3
  • 18
    • 31144448185 scopus 로고    scopus 로고
    • Should bisphosphonates be continued indefinitely? An unusual fracture in a healthy woman on long-term alendronate
    • Schneider JP: Should bisphosphonates be continued indefinitely? An unusual fracture in a healthy woman on long-term alendronate. Geriatrics 2006, 61:31-33.
    • (2006) Geriatrics , vol.61 , pp. 31-33
    • Schneider, J.P.1
  • 19
    • 67649742849 scopus 로고    scopus 로고
    • Case reports: Two femoral insufficiency fractures after long-term alendronate therapy
    • Sayed-Noor AS, Sjoden GO: Case reports: two femoral insufficiency fractures after long-term alendronate therapy. Clin Orthop Relat Res 2009, 467:1921-1926.
    • (2009) Clin Orthop Relat Res , vol.467 , pp. 1921-1926
    • Sayed-Noor, A.S.1    Sjoden, G.O.2
  • 20
    • 18444401127 scopus 로고    scopus 로고
    • Bilateral middiaphyseal femoral stress fractures in the elderly
    • Husada G, Libbeerecht K, Peeters T, Populaire J: Bilateral middiaphyseal femoral stress fractures in the elderly. Eur J Trauma 2005, 35:68-71.
    • (2005) Eur J Trauma , vol.35 , pp. 68-71
    • Husada, G.1    Libbeerecht, K.2    Peeters, T.3    Populaire, J.4
  • 21
    • 15944413442 scopus 로고    scopus 로고
    • Severely suppressed bone turnover: A potential complication of alendronate therapy
    • Odvina CV, Zerwekh JE, Rao DS, et al.: Severely suppressed bone turnover: a potential complication of alendronate therapy. J Clin Endocrinol Metab 2005, 90:1294-1301.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1294-1301
    • Odvina, C.V.1    Zerwekh, J.E.2    Rao, D.S.3
  • 22
    • 20844432225 scopus 로고    scopus 로고
    • Differential effects of teriparatide and alendronate on bone remodeling in postmenopausal women assessed by histomorphometric parameters
    • Arlot M, Meunier PJ, Boivin G, et al.: Differential effects of teriparatide and alendronate on bone remodeling in postmenopausal women assessed by histomorphometric parameters. J Bone Miner Res 2005, 20:1244-1253.
    • (2005) J Bone Miner Res , vol.20 , pp. 1244-1253
    • Arlot, M.1    Meunier, P.J.2    Boivin, G.3
  • 23
    • 68849119205 scopus 로고    scopus 로고
    • Low-energy femoral fractures associated with the long-term use of bisphosphonates: A case series from a Swiss university hospital
    • Ing-Lorenzini K, Desmeules J, Plachta O, et al.: Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital. Drug Saf 2009, 32:775-785.
    • (2009) Drug Saf , vol.32 , pp. 775-785
    • Ing-Lorenzini, K.1    Desmeules, J.2    Plachta, O.3
  • 24
    • 70449901284 scopus 로고    scopus 로고
    • Bilateral low-energy simultaneous or sequential femoral fractures in patients on long-term alendronate therapy
    • Capeci CM, Tejwani NC: Bilateral low-energy simultaneous or sequential femoral fractures in patients on long-term alendronate therapy. J Bone Joint Surg Am 2009, 91:2556-2561.
    • (2009) J Bone Joint Surg Am , vol.91 , pp. 2556-2561
    • Capeci, C.M.1    Tejwani, N.C.2
  • 25
    • 67650468390 scopus 로고    scopus 로고
    • Association of lowenergy femoral fractures with prolonged bisphosphonate use: A case control study
    • This study attempts to determine the risk factors for low-energy femoral fractures compared with a control group of patients with classic osteoporosis-related hip fractures of the femoral neck and intertrochanteric region. Bisphosphonate use was observed in 15 of the 41 subtrochanteric and shaft cases, compared with nine of the 82 hip fracture control subjects (OR, 4.44; 95% CI, 1.77-11.35). Patients with subtrochanteric/shaft fractures cases were more likely to be on long-term bisphosphonates than those with intertrochanteric and femoral neck fractures
    • Lenart BA, Neviaser AS, Lyman S, et al.: Association of lowenergy femoral fractures with prolonged bisphosphonate use: a case control study. Osteoporos Int 2009, 20:1353-1362. This study attempts to determine the risk factors for low-energy femoral fractures compared with a control group of patients with classic osteoporosis-related hip fractures of the femoral neck and intertrochanteric region. Bisphosphonate use was observed in 15 of the 41 subtrochanteric and shaft cases, compared with nine of the 82 hip fracture control subjects (OR, 4.44; 95% CI, 1.77-11.35). Patients with subtrochanteric/shaft fractures cases were more likely to be on long-term bisphosphonates than those with intertrochanteric and femoral neck fractures.
    • (2009) Osteoporos Int , vol.20 , pp. 1353-1362
    • Lenart, B.A.1    Neviaser, A.S.2    Lyman, S.3
  • 26
    • 66349094278 scopus 로고    scopus 로고
    • Subtrochanteric and diaphyseal femur fractures in patients treated with alendronate: A register-based national cohort study
    • Abrahamsen B, Eiken P, Eastell R: Subtrochanteric and diaphyseal femur fractures in patients treated with alendronate: a register-based national cohort study. J Bone Miner Res 2009, 24:1095-1102.
    • (2009) J Bone Miner Res , vol.24 , pp. 1095-1102
    • Abrahamsen, B.1    Eiken, P.2    Eastell, R.3
  • 27
    • 76549133448 scopus 로고    scopus 로고
    • Fragility fractures of the hip and femur: Incidence and patient characteristics
    • May 30 [Epub ahead of print]. The overall incidence of subtrochanteric and shaft fractures combined was less than 30/100,000 person-years. Although this study could not look at the specific radiologic pattern discussed in the case series, the incidence estimates should provide an upper limit of the number of the specific fractures discussed here
    • ·· Nieves JW, Bilezikian JP, Lane JM, et al.: Fragility fractures of the hip and femur: incidence and patient characteristics. Osteoporos Int 2009 May 30 [Epub ahead of print]. The overall incidence of subtrochanteric and shaft fractures combined was less than 30/100,000 person-years. Although this study could not look at the specific radiologic pattern discussed in the case series, the incidence estimates should provide an upper limit of the number of the specific fractures discussed here.
    • (2009) Osteoporos Int
    • Nieves, J.W.1    Bilezikian, J.P.2    Lane, J.M.3
  • 28
    • 0029932219 scopus 로고    scopus 로고
    • Are the etiologies of cervical and trochanteric hip fractures different?
    • Mautalen CA, Vega EM, Einhorn TA: Are the etiologies of cervical and trochanteric hip fractures different? Bone 1996, 18(3 Suppl):133S-137S.
    • (1996) Bone , vol.18 , Issue.3 SUPPL.
    • Mautalen, C.A.1    Vega, E.M.2    Einhorn, T.A.3
  • 30
    • 52949091144 scopus 로고    scopus 로고
    • Case report of spontaneous, nonspinal fractures in a multiple myeloma patient on long-term pamidronate and zoledronic acid
    • Wernecke G, Namduri S, Dicarlo EF, et al.: Case report of spontaneous, nonspinal fractures in a multiple myeloma patient on long-term pamidronate and zoledronic acid. HSS J 2008, 4:123-127.
    • (2008) HSS J , vol.4 , pp. 123-127
    • Wernecke, G.1    Namduri, S.2    Dicarlo, E.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.