In vitro anti-angiogenic properties of LGD1069, a selective retinoid X-receptor agonist through down-regulating Runx2 expression on Human endothelial cells

BMC Cancer

Volumn 11, Issue , 2011, Pages

  Fu, Jianjiang ^a   Wang, Wei ^a   Liu, Yu Hui ^a   Lu, Hong ^a   Luo, Yongming ^a  

^a JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Angiogenesis; LGD1069; Metastasis; Retinoid X receptor; Runx2

Indexed keywords

BETA ACTIN; BEXAROTENE; GELATINASE A; GELATINASE B; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; ANGIOGENESIS INHIBITOR; MATRIX METALLOPROTEINASE; RETINOID X RECEPTOR; TETRALIN DERIVATIVE;

ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING MOTIF; DOWN REGULATION; DRUG EFFICACY; ENDOTHELIUM CELL; GENE REPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS INHIBITION; MIGRATION INHIBITION; MITOSIS INHIBITION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CELL ADHESION; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANGIOGENESIS INHIBITORS; CELL ADHESION; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; MATRIX METALLOPROTEINASES; RETINOID X RECEPTORS; SMAD2 PROTEIN; SMAD3 PROTEIN; TETRAHYDRONAPHTHALENES;

EID: 79957956218     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-227     Document Type: Article

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