Neurocan contributes to the molecular heterogeneity of the perinodal ECM

Archives of Histology and Cytology

Volumn 73, Issue 2, 2011, Pages 95-102

  Bekku, Yoko ^a   Oohashi, Toshitaka ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROCAN;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; C57BL MOUSE; CEREBELLUM; CYTOLOGY; EXTRACELLULAR MATRIX; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY; METABOLISM; MOUSE; OPTIC NERVE; RANVIER NODE; STAINING; WESTERN BLOTTING;

ANIMALS; ANTIBODY SPECIFICITY; BLOTTING, WESTERN; CEREBELLUM; EXTRACELLULAR MATRIX; FLUORESCENT ANTIBODY TECHNIQUE; MICE; MICE, INBRED C57BL; NEUROCAN; OPTIC NERVE; RANVIER'S NODES; STAINING AND LABELING;

EID: 79957954936     PISSN: 09149465     EISSN: 13491717     Source Type: Journal    
DOI: 10.1679/aohc.73.95     Document Type: Article

References (26)

1. Asher RA, Morgenstern DA, Fidler PS, Adcock KH, Oohira A, Braistead JE, Levine JM, Margolis RU, Rogers JH, Fawcett JW: Neurocan is upregulated in injured brain and in cytokine-treated astrocytes. J Neurosci 20: 2427-2438 (2000).
2. Aspberg A, Miura R, Bourdoulous S, Shimonaka M, Heinegard D, Schachner M, Ruoslahti E, Yamaguchi Y: The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety. Proc Natl Acad Sci USA 94: 10116-10121 (1997).
3. Bandtlow CE, Zimmermann DR: Proteoglycans in the developing brain: new conceptual insights for old proteins. Physiol Rev 80: 1267-1290 (2000).
4. Bekku Y, Su WD, Hirakawa S, Fässler R, Ohtsuka A, Kang JS, Sanders J, Murakami T, Ninomiya Y, Oohashi T: Molecular cloning of Bral2, a novel brain-specific link protein, and immunohistochemical colocalization with brevican in perineuronal nets. Mol Cell Neurosci 24: 148-159 (2003).
5. Bekku Y, Rauch U, Ninomiya Y, Oohashi T: Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS. J Neurochem 108: 1266-1276 (2009).
6. Bekku Y, Vargová L, Goto Y, Vorísek I, Dmytrenko L, Narasaki M, Ohtsuka A, Fässler R, Ninomiya Y, Syková E, Oohashi T: Bral1: its role in diffusion barrier formation and conduction velocity in the CNS. J Neurosci 30: 3113-3123 (2010).
7. Celio MR, Spreafico R, De Biasi S, Vitellaro-Zuccarello L: Perineuronal nets: past and present. Trends Neurosci 21: 510-5 (1998).
8. Dours-Zimmermann MT, Maurer K, Rauch U, Stoffel W, Fässler R, Zimmermann DR: Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS. J Neurosci 29: 7731-7742 (2009).
9. Engel M, Maurel P, Margolis RU, Margolis RK: Chondroitin sulfate proteoglycans in the developing central nervous system. I. cellular sites of synthesis of neurocan and phosphacan. J Comp Neurol 366: 34-43 (1996).
10. Hirakawa S, Oohashi T, Su WD, Yoshioka H, Murakami T, Arata J, Ninomiya Y: The brain link protein-1 (BRAL1): cDNA cloning, genomic structure, and characterization as a novel link protein expressed inadult brain. Biochem Biophys Res Commun 276: 982-989 (2000).
11. Matsui F, Nishizuka M, Yasuda Y, Aono S, Watanabe E, Oohira A: Occurrence of a N-terminal proteolytic fragment of neurocan, not a C-terminal half, in a perineuronal net in the adult rat cerebrum. Brain Res 790: 45-51 (1998).
12. Matsui F, Oohaira A: Structure and function of neurocan, a nervous-tissue chondroitin sulfate proteoglycan. In: Neural Proteoglycans (Maeda N, ed), Research Signpost, India, 2007 (p. 21-36)
13. Meyer-Puttlitz B, Milev P, Junker E, Zimmer I, Margolis RU, Margolis RK: Chondroitin sulfate and chondroitin/ keratan sulfate proteoglycans of nervous tissue: developmental changes of neurocan and phosphacan. J Neurochem 65: 2327-2337 (1995).
14. Milev P, Maurel P, Chiba A, Mevissen M, Popp S, Yamaguchi Y, Margolis RK, Margolis RU: Differential regulation of expression of hyaluronan-binding proteoglycans in developing brain: aggrecan, versican, neurocan, and brevican. Biochem Biophys Res Commun 247: 207-212 (1998).
15. Miyata S, Nishimura Y, Hayashi N, Oohira A: Construction of perineuronal net-like structure by cortical neurons in culture. Neuroscience 136: 95-104 (2005).
16. Nicholson C, Phillips JM: Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum. J Physiol 321: 225-257 (1981).
17. Olin AI, Mörgelin M, Sasaki T, Timpl R, Heinegård D, Aspberg A: The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding. J Biol Chem 276: 1253-1261 (2001).
18. Oohashi T, Hirakawa S, Bekku Y, Rauch U, Zimmermann DR, Su WD, Ohtsuka A, Murakami T, Ninomiya Y: Bral1, a brain-specific link protein, colocalizing with the versican V2 isoform at the nodes of Ranvier in developing and adult mouse central nervous systems. Mol Cell Neurosci 19: 43-57 (2002).
19. Oohashi T, Bekku Y: Brain Link Proteins: Neuromodulators for scaffolding the specialized hyaluronan-binding extracellular milieu in the brain. In: Neural Proteoglycans (Maeda N, ed), Research Signpost, India, 2007 (p. 67-83).
20. Oohira A, Matsui F, Watanabe E, Kushima Y, Maeda N: Developmentally regulated expression of a brain specific species of chondroitin sulfate proteoglycan, neurocan, identified with a monoclonal antibody IG2 in the rat cerebrum. Neuroscience 60: 145-157 (1994).
21. Pizzorusso T, Medini P, Berardi N, Chierzi S, Fawcett JW, Maffei L: Reactivation of ocular dominance plasticity in the adult visual cortex. Science 298: 1248-1251 (2002).
22. Rauch U, Gao P, Janetzko A, Flaccus A, Hilgenberg L, Tekotte H, Margolis RK, Margolis RU: Isolation and characterization of developmentally regulated chondroitin sulfate and chondroitin/keratan sulfate proteoglycans of brain identified with monoclonal antibodies. J Biol Chem 266: 14785-14801 (1991).
23. Rhodes KE, Fawcett JW: Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS? J Anat 204: 33-48 (2004).
24. Schmalfeldt M, Bandtlow CE, Dours-Zimmermann MT, Winterhalter KH, Zimmermann DR: Brain derived versican V2 is a potent inhibitor of axonal growth. J Cell Sci 113: 807-816 (2000).
25. Sykova E, Nicholson C: Diffusion in brain extracellular space: Physiol Rev 88: 1277-1340 (2008).
26. Zhou XH, Brakebusch C, Matthies H, Oohashi T, Hirsch E, Moser M, Krug M, Seidenbecher CI, Boeckers TM, Rauch U, Buettner R, Gundelfinger ED, Fässler R: Neurocan is dispensable for brain development. Mol Cell Biol 21: 5970-5978 (2001).