Cytokeratin 7 and 20 expression in Gallbladder carcinoma

Polish Journal of Pathology

Volumn 62, Issue 1, 2011, Pages 25-30

  Kalekou, Harikleia ^a   Miliaras, Dimosthenis ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Cytokeratin 20; Cytokeratin 7; Gallbladder carcinoma; P53 protein

Indexed keywords

CYTOKERATIN 20; CYTOKERATIN 7; TUMOR MARKER;

ADENOCARCINOMA; AGED; ARTICLE; CHOLECYSTITIS; CHRONIC DISEASE; ENZYME IMMUNOASSAY; GALLBLADDER; GALLBLADDER TUMOR; HUMAN; METABOLISM; METHODOLOGY; MIDDLE AGED; MUCOSA; PATHOLOGY;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; CHOLECYSTITIS; CHRONIC DISEASE; GALLBLADDER; GALLBLADDER NEOPLASMS; HUMANS; IMMUNOENZYME TECHNIQUES; KERATIN-20; KERATIN-7; MIDDLE AGED; MUCOUS MEMBRANE; TUMOR MARKERS, BIOLOGICAL;

EID: 79957933905     PISSN: 12339687     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Moll R, Divo M, Langbein L. The human keratins: biology and pathology. Histochem Cell Biol 2008; 129: 705-733.
2. Schweizer J, Bowden PE, Coulombe PA, et al. New consensus nomenclature for mammalian keratins. J Cell Biol 2006; 174: 169-174.
3. Moll R. Cytokeratins as markers of differentiation in the diagnosis of epithelial tumors. Subcell Biochem 1998; 31: 205-262.
4. Rosenberg M, Fuchs E, Le Beau MM, et al. Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12. Cytogenet Cell Genet 1991; 57: 33-38.
5. Glass C, Fuchs E. Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells. J Cell Biol 1998; 107: 1337-1350.
6. Moll R, Zimbelmann R, Goldschmidt MD, et al. The human gene encoding cytokeratin 20 and its expression during fetal development and in gastrointestinal carcinomas. Differentiation 1993; 53: 75-93.
7. Chu P, Wu E, Weiss LM. Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Mod Pathol 2000; 13: 962-972.
8. McCluggage WG, Young RH. Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors. Sem Diagn Pathol 2005; 22: 3-32.
9. Saad RS, Silverman JF, Khalifa MA, et al. CDX2, cytokeratins 7 and 20 immunoreactivity in rectal adenocarcinoma. Appl Immunohistochem Mol Morphol 2009; 17: 196-201.
10. Al-Zahrani IH. The value of immunohistochemical expression of TTF-1, CK7 and CK20 in the diagnosis of primary and secondary lung carcinomas. Saudi Med J 2008; 29: 957-961.
11. Chang HJ, Kim SW, Lee BL, et al. Phenotypic alterations of mucins and cytokeratins during gallbladder carcinogenesis. Pathol Int 2004; 54: 576-584.
12. Duval JV, Savas L, Banner BF. Expression of cytokeratins 7 and 20 in carcinomas of the extrahepatic biliary tract, pancreas, and gallbladder. Arch Pathol Lab Med 2000; 124: 1196-1200.
13. Cabibi D, Licata A, Barresi E, et al. Expression of cytokeratin 7 and 20 in pathological conditions of the bile tract. Pathol Res Pract 2003; 199: 65-70.
14. Shimonishi T, Miyazaki K, Nakanuma Y. Cytokeratin profile relates to histological subtypes and intrahepatic location of intrahepatic cholangiocarcinoma and primary sites of metastatic adenocarcinoma of liver. Histopathology 2000; 37: 55-63.
15. Cooper DS, Schermer A, Sun TT. Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations. Lab Invest 1985; 52: 243-256.
16. Laitio M. Goblet cells, enterochromaffin cells, superficial gastric-type epithelium and antral-type glands in the gallbladder. Beitr Pathol 1975; 156: 343-358.
17. Loy TS, Calaluce RD, Keeney GL. Cytokeratin immunostain-ing in differentiating primary ovarian carcinoma from metastatic colonic adenocarcinoma. Mod Pathol 1996; 9: 1040-1044.
18. Ueda G, Sawada M, Ogawa H, et al. Immunohistochemical study of cytokeratin 7 for the differential diagnosis of adenocarcinomas in the ovary. Gynecol Oncol 1993; 51: 219-223.
19. Wang NP, Zee S, Zarbo RJ, et al. Coordinate expression of cytokeratins 7 and 20 defines unique subsets of carcinomas. Appl Immunohistochem 1995; 3: 99-107.
20. Wauters CC, Smedts F, Gerrits LG, et al. Keratin 7 and 20 as diagnostic markers of carcinomas metastatic to the ovary. Hum Pathol 1995; 26: 852-855.
21. Loy TS, Calaluce RD. Utility of cytokeratin immunostaining in separating pulmonary adenocarcinomas from colonic adenocarcinomas. Am J Clin Pathol 1994; 102: 764-767.
22. van de Molengraft FJJM, van Niekerk CC, Jap PH, et al. OV-TL 12/30 (keratin 7 antibody) is a marker of glandular differentiation in lung cancer. Histopathology 1993; 22: 35-38.
23. Kaufmann O, Deidesheimer T, Muehlenberg M, et al. Immunohistochemical differentiation of metastatic breast car cinomas from metastatic adenocarcinomas of other common primary sites. Histopathology 1996; 3: 233-240.
24. Maeda T, Adachi E, Kajiyama K, et al. Combined hepatocellular and cholangiocarcinoma: proposed criteria according to cytokeratin expression and analysis of clinicopathologic features. Hum Pathol 1995; 26: 956-964.
25. Royds JA, Iacopetta B. p53 and disease: when the guardian angel fails. Cell Death Differ 2006; 13: 1017-1026.