An experimental mouse model to establish Tropheryma whipplei as a diarrheal agent

Journal of Infectious Diseases

Volumn 204, Issue 1, 2011, Pages 44-50

  Al Moussawi, Khatoun ^a   Malou, Nada ^a   Mege, Jean Louis ^a   Raoult, Didier ^a   Desnues, Benoit ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN SULFATE; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 6; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ARTICLE; BACTERIAL GROWTH; BACTERIAL TRANSMISSION; BACTERIUM DETECTION; CONTROLLED STUDY; DIARRHEA; FECES; GASTROENTERITIS; IMMUNE RESPONSE; IMMUNOASSAY; INTESTINE MUCOSA; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TROPHERYMA WHIPPELII;

ANIMALS; ANTIBODIES, BACTERIAL; COLON; DIARRHEA; DISEASE MODELS, ANIMAL; FECES; FEMALE; GASTROENTERITIS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MICE; MICE, INBRED C57BL; RODENT DISEASES; TROPHERYMA; WHIPPLE DISEASE;

EID: 79957931615     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir219     Document Type: Article

References (27)

1. Fenollar F, Puechal X, Raoult D. Whipple's disease. N Engl J Med 2007; 356:55-66. (Pubitemid 46041754)
2. Schoniger-Hekele M, Petermann D, Weber B, Muller C. Tropheryma whipplei in the environment: survey of sewage plant influxes and sewage plant workers. Appl Environ Microbiol 2007; 73:2033-5. (Pubitemid 46449093)
3. Amsler L, Bauernfeind P, Nigg C, Maibach RC, Steffen R, Altwegg M. Prevalence of Tropheryma whipplei DNA in patients with various gastrointestinal diseases and in healthy controls. Infection 2003; 31:81-5. (Pubitemid 36437720)
4. Fenollar F, Trani M, Davoust B, et al. Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates. J Infect Dis 2008; 197:880-7. (Pubitemid 351417012)
5. Fenollar F, Laouira S, Lepidi H, Rolain JM, Raoult D. Value of Tropheryma whipplei quantitative polymerase chain reaction assay for the diagnosis of Whipple disease: usefulness of saliva and stool specimens for first-line screening. Clin Infect Dis 2008; 47:659-67.
6. Greub G. A new piece added to the whipple puzzle: Tropheryma whipplei primary infection with bacteremia and cough. Clin Infect Dis 2010; 51:522-4.
7. Fenollar F, Mediannikov O, Socolovschi C, et al. Tropheryma whipplei bacteremia during fever in Rural West Africa. Clin Infect Dis 2010; 51:515-21.
8. Bousbia S, Papazian L, Auffray JP, et al. Tropheryma whipplei in patients with pneumonia. Emerg Infect Dis 2010; 16:258-63.
9. Raoult D, Fenollar F, Rolain JM, et al. Tropheryma whipplei in children with gastroenteritis. Emerg Infect Dis 2010; 16:776-82.
10. Telfer S, Lambin X, Birtles R, et al. Species interactions in a parasite community drive infection risk in a wildlife population. Science 2010; 330:243-6.
11. Okayasu I, Hatakeyama S, Yamada M, Ohkusa T, Inagaki Y, Nakaya R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990; 98:694-702. (Pubitemid 20069706)
12. Axelsson LG, Landstrom E, Goldschmidt TJ, Gronberg A, Bylund-Fellenius AC. Dextran sulfate sodium (DSS) induced experimental colitis in immunodeficient mice: effects in CD4(+)-cell depleted, athymic and NK-cell depleted SCID mice. Inflamm Res 1996; 45:181-91. (Pubitemid 26135074)
13. Raoult D, Birg ML, La Scola B, et al. Cultivation of the bacillus of Whipple's disease. N Engl J Med 2000; 342:620-5. (Pubitemid 30118414)
14. Axelsson LG, Landstrom E, Bylund-Fellenius AC. Experimental colitis induced by dextran sulphate sodium in mice: beneficial effects of sulphasalazine and olsalazine. Aliment Pharmacol Ther 1998; 12:925-34. (Pubitemid 28428959)
15. Wirtz S, Neufert C, Weigmann B, Neurath MF. Chemically induced mouse models of intestinal inflammation. Nat Protoc 2007; 2:541-6. (Pubitemid 47040018)
16. Ghigo E, Capo C, Aurouze M, et al. Survival of Tropheryma whipplei, the agent of Whipple's disease, requires phagosome acidification. Infect Immun 2002; 70:1501-6. (Pubitemid 34163429)
17. Al Moussawi K, Ghigo E, Kalinke U, Alexopoulou L, Mege JL, Desnues B. Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei. PLoS Pathog 2010; 6:e1000722.
18. Honstettre A, Meghari S, Nunes JA, et al. Role for the CD28 molecule in the control of Coxiella burnetii infection. Infect Immun 2006; 74:1800-8. (Pubitemid 43346816)
19. Niemeyer CM, Adler M, Wacker R. Detecting antigens by quantitative immuno-PCR. Nat Protoc 2007; 2:1918-30. (Pubitemid 47308130)
20. Heimesaat MM, Fischer A, Siegmund B, et al. Shift towards proinflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4. PLoS One 2007; 2:e662.
21. Onyeagocha C, Hossain MS, Kumar A, Jones RM, Roback J, Gewirtz AT. Latent cytomegalovirus infection exacerbates experimental colitis. Am J Pathol 2009; 175:2034-42.
22. Rabizadeh S, Rhee KJ, Wu S, et al. Enterotoxigenic bacteroides fragilis: a potential instigator of colitis. Inflamm Bowel Dis 2007; 13:1475-83.
23. Vowinkel T, Anthoni C, Wood KC, et al. CD40-CD40 ligand mediates the recruitment of leukocytes and platelets in the inflamed murine colon. Gastroenterology 2007; 132:955-65. (Pubitemid 46440860)
24. Genot S, Stein A, Lepidi H, Ihrig M, Raoult D, Mege JL. Murine model of infection by Tropheryma whipplei. Infect Immun 2006; 74:4915-7. (Pubitemid 44157280)
25. Bonhomme CJ, Renesto P, Desnues B, et al. Tropheryma whipplei glycosylation in the pathophysiologic profile of Whipple's disease. J Infect Dis 2009; 199:1043-52.
26. Bonhomme CJ, Renesto P, Nandi S, Lynn AM, Raoult D. Serological microarray for a paradoxical diagnostic of Whipple's disease. Eur J Clin Microbiol Infect Dis 2008; 27:959-68.
27. Fenollar F, Amphoux B, Raoult D. A paradoxical Tropheryma whipplei western blot differentiates patients with whipple disease from asymptomatic carriers. Clin Infect Dis 2009; 49:717-23.