Cultivation of the bacillus of Whipple's disease

New England Journal of Medicine

Volumn 342, Issue 9, 2000, Pages 620-625

  Raoult, Didier ^a   Birg, Marie L ^a   La Scola, Bernard ^a   Fournier, Pierre E ^a   Enea, Maryse ^a   Lepidi, Hubert ^a   Roux, Veronique ^a   Piette, Jean Charles ^b   Vandenesch, François ^c   Vital Durand, Denis ^d   Marrie, Tom J ^e  

^a AIX MARSEILLE UNIVERSITY   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c LOUIS PRADEL HOSPITAL   (France)

^d CENTRE HOSPITALIER LYON SUD   (France)

^e UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM ANTIBODY; IMMUNOGLOBULIN M; POLYCLONAL ANTIBODY; RNA 16S;

ANTIBODY PRODUCTION; ARTICLE; BACILLUS; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; ENDOCARDITIS; FIBROBLAST; INTESTINE LIPODYSTROPHY; NONHUMAN; PRIORITY JOURNAL; SERODIAGNOSIS; TROPHERYMA WHIPPELII;

ACTINOBACTERIA; ADULT; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIOLOGICAL TECHNIQUES; CELL LINE; ENDOCARDITIS, BACTERIAL; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MICE; MICE, INBRED BALB C; MITRAL VALVE; WHIPPLE DISEASE;

EID: 0034594873     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200003023420903     Document Type: Article

References (29)

1. Vital-Durand D, Lecomte C, Cathebras P, Rousset H, Godeau P. Whipple disease: clinical review of 52 cases. Medicine (Baltimore) 1997;76:170-84.
2. Ratliff NB, McMahon JT, Naab TJ, Cosgrove DM. Whipple's disease in the porcine leaflets of a Carpentier-Edwards prosthetic mitral valve. N Engl J Med 1984;311:902-3.
3. Maizel H, Ruffin JM, Dobbins WO III. Whipple's disease: a review of 19 patients from one hospital and a review of the literature since 1950. Medicine (Baltimore) 1970;49:175-205.
4. Whipple GH. A hitherto undescribed disease characterized anatomically by deposits of fat and fatty acids in the intestinal and mesenteric lymphatic tissues. Bull Johns Hopkins Hosp 1907;18:382-91.
5. Yardley J, Hendrix TR. Combined electron and light microscopy in Whipple's disease: demonstration of "bacillary bones" in the intestine. Bull Johns Hopkins Hosp 1961;109:80-98.
6. Black-Schaffer B. The tinctoral demonstration of a glycoprotein in Whipple's disease. Proc Soc Exp Biol Med 1949;72:225-7.
7. Wilson KH, Blitchington R, Frothingham R, Wilson JAP. Phylogeny of the Whipple's-disease-associated bacterium. Lancet 1991;338:474-5.
8. Relman DA, Schmidt TM, MacDermott RP, Falkow S. Identification of the uncultured bacillus of Whipple's disease. N Engl J Med 1992;327:293-301.
9. Renne R, Zhong W, Herndier B, et al. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat Med 1996;2:342-6.
10. Ramzan NN, Loftus E Jr, Burgart LJ, et al. Diagnosis and monitoring of Whipple disease by polymerase chain reaction. Ann Intern Med 1997; 126:520-7.
11. Relman DA. The Whipple bacillus lives (ex vivo)! J Infect Dis 1997; 176:752-4.
12. Schoedon G, Goldenberger D, Forrer R, et al. Deactivation of macrophages with interleukin-4 is the key to the isolation of Tropheryma whippelii. J Infect Dis 1997;176:672-7.
13. Hinrikson HP, Dutly F, Nair S, Altwegg M. Detection of three different types of 'Tropheryma whippelii' directly from clinical specimens by sequencing, single-strand conformation polymorphism (SSCP) analysis and type-specific PCR of their 16S-23S ribosomal intergenic spacer region. Int J Syst Bacteriol 1999;49:1701-6.
14. Woods GL, Walker DH. Detection of infection or infectious agents by use of cytologic and histologic stains. Clin Microbiol Rev 1996;9:382-404.
15. La Scola B, Michel G, Raoult D. Isolation of Legionella pneumophila by centrifugation of shell vial cell cultures from multiple liver and lung abscesses. J Clin Microbiol 1999;37:785-7.
16. La Scola B, Raoult D. Diagnosis of Mediterranean spotted fever by cultivation of Rickettsia conorii from blood and skin samples using the centrifugation-shell vial technique and by detection of R. conorii in circulating endothelial cells: a 6-year follow-up. J Clin Microbiol 1996;34: 2722-7.
17. Giménez DF. Staining rickettsiae in yolk-sac cultures. Stain Technol 1964;39:135-40.
18. La Scola B, Birtles RJ, Mallet MN, Raoult D. Massilia timonae gen. nov., sp. nov., isolated from blood of an immunocompromised patient with cerebellar lesions. J Clin Microbiol 1998;36:2847-52.
19. La Scola B, Raoult D. Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). J Clin Microbiol 1999;37:1899-905.
20. Célard M, de Gevigney G, Mosnier S, et al. Polymerase chain reaction analysis for diagnosis of Tropheryma whippelii infective endocarditis in two patients with no previous evidence of Whipple's disease. Clin Infect Dis 1999;29:1348-9.
21. La Scola B, Michel G, Raoult D. Use of amplification and sequencing of the 16S rRNA gene to diagnose Mycoplasma pneumoniae osteomyelitis in a patient with hypogammaglobulinemia. Clin Infect Dis 1997;24:1161-3.
22. Bostwick DG, Bensch KG, Burke JS, et al. Whipple's disease presenting as aortic insufficiency. N Engl J Med 1981;305:995-8.
23. Rose A. Mitral stenosis in Whipple's disease. Thorax 1978;33:500-3.
24. Silva MT, Macedo PM, Moura Nunes JF. Ultrastructure of bacilli and the bacillary origin of the macrophagic inclusions in Whipple's disease. J Gen Microbiol 1985;131:1001-13.
25. Murray RGE, Schleifer KH. Taxonomic notes: a proposal for recording the properties of putative taxa of procaryotes. Int J Syst Bacteriol 1994; 44:174-6.
26. Shepard CC. The experimental disease that follows the injection of human leprosy bacilli into foot-pads of mice. J Exp Med 1960;112:445-54.
27. Slater LN, Welch DF, Hensel D, Coody DW. A newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia. N Engl J Med 1990;323:1587-93.
28. Marshall B. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1983;1:1273-5.
29. Weiss E, Dressier HR. Centrifugation of rickettsiae and viruses onto cells and its effect on infection. Proc Soc Exp Biol Med 1960;103:691-5.