Genome-wide association identifies diverse causes of common variable immunodeficiency

Journal of Allergy and Clinical Immunology

Volumn 127, Issue 6, 2011, Pages

  Orange, Jordan S ^a   Glessner, Joseph T ^b   Resnick, Elena ^c   Sullivan, Kathleen E ^a   Lucas, Mary ^d   Ferry, Berne ^d   Kim, Cecilia E ^b   Hou, Cuiping ^b   Wang, Fengxiang ^b   Chiavacci, Rosetta ^b   Kugathasan, Subra ^e   Sleasman, John W ^f   Baldassano, Robert ^a   Perez, Elena E ^f   Chapel, Helen ^d   Cunningham Rundles, Charlotte ^c   Hakonarson, Hakon ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

antibody deficiency; common variable immunodeficiency; copy number variation; genetics; genome wide association; immunodiagnostics; Primary immunodeficiency

Indexed keywords

ADAM PROTEIN; DISINTEGRIN; ORIGIN RECOGNITION COMPLEX; ORIGIN RECOGNITION COMPLEX 4L; UNCLASSIFIED DRUG;

ARTICLE; CHILD; COMMON VARIABLE IMMUNODEFICIENCY; COMORBIDITY; CONTROLLED STUDY; COPY NUMBER VARIATION; EXON; GENE; GENE DELETION; GENE DUPLICATION; GENE REPLICATION; GENETIC ANALYSIS; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; PHENOTYPE; PRIORITY JOURNAL; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 79957874121     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.02.039     Document Type: Article

References (4)

1. Vapnik V. The nature of statistical learning theory. New York: Springer-Verlag; 1995.
2. Chang C-C, Lin C-J. LIBSVM: a library for support vector machines, 2001. Available at: http://www.csie.ntu.edu.tw/~cjlin/libsvm/. Accessed March 16, 2011.
3. Hsu CW, Chang CC, Lin CJ. A practical guide to support vector classification, 2003, updated 2010. Available at: http://www.csie.ntu.edu.tw/ ~cjlin/papers/guide/guide.pdf. Accessed March 16, 2011.
4. Wei Z, Wang K, Qu HQ, Zhang H, Bradfield J, Kim C, et al. From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes. PLoS Genet 2009;5:e1000678.