The monoamine oxidase (MAO) inhibitor tranylcypromine enhances nicotine self-administration in rats through a mechanism independent of MAO inhibition

Neuropharmacology

Volumn 61, Issue 1-2, 2011, Pages 95-104

  Lotfipour, Shahrdad ^a,b   Arnold, Monica M ^a   Hogenkamp, Derk J ^a   Gee, Kelvin W ^a   Belluzzi, James D ^a   Leslie, Frances M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dopamine; Microdialysis; Monoamine oxidase; Serotonin; Stereoisomers

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; DOPAMINE; KETANSERIN; MECAMYLAMINE; MONOAMINE OXIDASE INHIBITOR; NICOTINE; NICOTINIC RECEPTOR; SEROTONIN; TRANYLCYPROMINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG EFFICACY; DRUG SELF ADMINISTRATION; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; NUCLEUS ACCUMBENS; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; REINFORCEMENT; SEROTONIN RELEASE; STEREOISOMERISM;

ANIMALS; BEHAVIOR, ADDICTIVE; BRAIN; DOPAMINE; MALE; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; NICOTINE; RATS; RATS, SPRAGUE-DAWLEY; SELF ADMINISTRATION; SEROTONIN; TRANYLCYPROMINE;

EID: 79957871478     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.03.007     Document Type: Article

References (54)

1. ACS, 2010. Cancer Facts & Figures 2010. American Cancer Society, Atlanta.
2. Aspeslet, L.J., Baker, G.B., Coutts, R.T., Mousseau, D.D., 1992. A gas chromatographic procedure for separation and quantitation of the enantiomers of the antidepressant tranylcypromine. Biochem. Pharmacol. 44, 1894-1897.
3. Baker, G.B., Coutts, R.T., McKenna, K.F., Sherry-McKenna, R.L., 1992. Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review. J. Psychiatry Neurosci. 17, 206-214. (Pubitemid 23141096)
4. Baker, G.B., Sowa, B., Todd, K.G., 2007. Amine oxidases and their inhibitors: what can they tell us about neuroprotection and the development of drugs for neuropsychiatric disorders? J. Psychiatry Neurosci. 32, 313-315. (Pubitemid 47492755)
5. Belluzzi, J.D., Lee, A.G., Oliff, H.S., Leslie, F.M., 2004. Age-dependent effects of nicotine on locomotor activity and conditioned place preference in rats. Psychopharmacology (Berl) 174, 389-395. (Pubitemid 39044297)
6. Belluzzi, J.D., Wang, R., Leslie, F.M., 2005. Acetaldehyde enhances acquisition of nicotine self-administration in adolescent rats. Neuropsychopharmacology 30, 705-712. (Pubitemid 40397076)
7. Berlin, I., Anthenelli, R.M., 2001. Monoamine oxidases and tobacco smoking. Int. J. Neuropsychopharmacol. 4, 33-42.
8. Bohadana, A., Nilsson, F., Rasmussen, T., Martinet, Y., 2000. Nicotine inhaler and nicotine patch as a combination therapy for smoking cessation: a randomized, double-blind, placebo-controlled trial. Arch. Intern. Med. 160, 3128-3134.
9. CDC, 2008. Annual Smoking-Attributable Mortality, Years of Potential Life Lost, and Productivity Losses - United States, 2000-2004. In: CDC, (Ed.), Morbidity and Mortality Weekly Report 2008, pp. 1226-1228.
10. Chaudhri, N., Caggiula, A.R., Donny, E.C., Palmatier, M.I., Liu, X., Sved, A.F., 2006. Complex interactions between nicotine and nonpharmacological stimuli reveal multiple roles for nicotine in reinforcement. Psychopharmacology (Berl) 184, 353-366. (Pubitemid 43255852)
11. Clemens, K.J., Caille, S., Stinus, L., Cador, M., 2009. The addition of five minor tobacco alkaloids increases nicotine-induced hyperactivity, sensitization and intravenous self-administration in rats. Int. J. Neuropsychopharmacol. 12, 1355-1366.
12. Clemens, K.J., Caille, S., Cador, M., 2010. The effects of response operandum and prior food training on intravenous nicotine self-administration in rats. Psychopharmacology (Berl) 211, 43-54.
13. De Vries, T.J., de Vries, W., Janssen, M.C., Schoffelmeer, A.N., 2005. Suppression of conditioned nicotine and sucrose seeking by the cannabinoid-1 receptor antagonist SR141716A. Behav. Brain Res. 161, 164-168.
14. Di Matteo, V., Cacchio, M., Di Giulio, C., Esposito, E., 2002. Role of serotonin(2C) receptors in the control of brain dopaminergic function. Pharmacol. Biochem. Behav. 71, 727-734.
15. Diergaarde, L., Pattij, T., Poortvliet, I., Hogenboom, F., de Vries, W., Schoffelmeer, A.N., De Vries, T.J., 2008. Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats. Biol. Psychiatry 63, 301-308.
16. Donny, E.C., Caggiula, A.R., Mielke, M.M., Jacobs, K.S., Rose, C., Sved, A.F., 1998. Acquisition of nicotine self-administration in rats: the effects of dose, feeding schedule, and drug contingency. Psychopharmacology (Berl) 136, 83-90. (Pubitemid 28097524)
17. Filip, M., Nowak, E., Papla, I., 2001. On the role of serotonin2A/2C receptors in the sensitization to cocaine. J. Physiol. Pharmacol. 52, 471-481.
18. Fowler, J.S., Volkow, N.D., Wang, G.J., Pappas, N., Logan, J., MacGregor, R., Alexoff, D., Shea, C., Schlyer, D., Wolf, A.P., Warner, D., Zezulkova, I., Cilento, R., 1996a. Inhibition of monoamine oxidase B in the brains of smokers. Nature 379, 733-736. (Pubitemid 26061736)
19. Fowler, J.S., Volkow, N.D., Wang, G.J., Pappas, N., Logan, J., Shea, C., Alexoff, D., MacGregor, R.R., Schlyer, D.J., Zezulkova, I., Wolf, A.P., 1996b. Brain monoamine oxidase A inhibition in cigarette smokers. Proc. Natl. Acad. Sci. U S A 93, 14065-14069.
20. Franke, R.M., Park, M., Belluzzi, J.D., Leslie, F.M., 2008. Prenatal nicotine exposure changes natural and drug-induced reinforcement in adolescent male rats. Eur. J. Neurosci. 27, 2952-2961.
21. Fuentes, J.A., Oleshansky, M.A., Neff, N.H., 1976. Comparison of the apparent anti-depressant activity of (-) and (+) tranylcypromine in an animal model. Biochem. Pharmacol. 25, 801-804.
22. Guillem, K., Vouillac, C., Azar, M.R., Parsons, L.H., Koob, G.F., Cador, M., Stinus, L., 2005. Monoamine oxidase inhibition dramatically increases the motivation to self-administer nicotine in rats. J. Neurosci. 25, 8593-8600. (Pubitemid 41362035)
23. Guillem, K., Vouillac, C., Azar, M.R., Parsons, L.H., Koob, G.F., Cador, M., Stinus, L., 2006. Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats. Eur. J. Neurosci. 24, 3532-3540.
24. Guillem, K., Vouillac, C., Koob, G.F., Cador, M., Stinus, L., 2008. Monoamine oxidase inhibition dramatically prolongs the duration of nicotine withdrawal-induced place aversion. Biol. Psychiatry 63, 158-163. (Pubitemid 350299328)
25. Hampson, D.R., Baker, G.B., Coutts, R.T., 1986. A comparison of the neurochemical properties of the stereoisomers of tranylcypromine in the central nervous system. Cell. Mol. Biol. 32, 593-599.
26. Henningfield, J.E., Miyasato, K., Jasinski, D.R., 1985. Abuse liability and pharmacodynamic characteristics of intravenous and inhaled nicotine. J. Pharmacol. Exp. Ther. 234, 1-12.
27. Horn, A.S., Snyder, S.H., 1972. Steric requirements for catecholamine uptake by rat brain synaptosomes: studies with rigid analogs of amphetamine. J. Pharmacol. Exp. Ther. 180, 523-530.
28. Kaiser, C., Lester, B.M., Zirkle, C.L., 1962. 2-Substituted cyclopropylamines. I. Derivatives and analogs of 2-phenylcyclopropylamine. J. Med. Pharm. Chem. 91, 1243-1265.
29. Khalil, A.A., Steyn, S., Castagnoli Jr., N., 2000. Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves. Chem. Res. Toxicol. 13, 31-35.
30. Leslie, F.M., Belluzzi, J.D., Lotfipour, S., Arnold, M., Villećgier, A.S., 2009. Positive Effects of Monoamine Oxidase Inhibitors on the Acquisition of Nicotine Self-administration in Rats. SRNT, Dublin, Ireland.
31. Levin, E., Icenogle, L., Farzad, A., 2005. Ketanserin attenuates nicotine-induced working memory improvement in rats. Pharmacol. Biochem. Behav. 82, 289-292.
32. Levin, E.D., Slade, S., Johnson, M., Petro, A., Horton, K., Williams, P., Rezvani, A.H., Rose, J.E., 2008. Ketanserin, a 5-HT2 receptor antagonist, decreases nicotine self-administration in rats. Eur. J. Pharmacol. 600, 93-97.
33. Lewis, A., Miller, J.H., Lea, R.A., 2007. Monoamine oxidase and tobacco dependence. Neurotoxicology 28, 182-195. (Pubitemid 46187252)
34. Lotfipour, S., Villégier, A.S., Belluzzi, J.D., Leslie, F.M., 2007. The Role of Monoamine Oxidase Inhibition in Tranylcypromine Enhancement of Nicotine Reward. Society for Neuroscience, San Diego, California.
35. McMahon, L.R., Cunningham, K.A., 2001. Antagonism of 5- hydroxytryptamine(2a) receptors attenuates the behavioral effects of cocaine in rats. J. Pharmacol. Exp. Ther. 297, 357-363.
36. Mokdad, A.H., Marks, J.S., Stroup, D.F., Gerberding, J.L., 2004. Actual causes of death in the United States, 2000. J Am Med Assoc 291, 1238-1245. (Pubitemid 38541668)
37. Nides, M., 2008. Update on pharmacologic options for smoking cessation treatment. Am. J. Med. 121, S20-S31.
38. O'Dell, L.E., Khroyan, T.V., 2009. Rodent models of nicotine reward: what do they tell us about tobacco abuse in humans? Pharmacol. Biochem. Behav. 91, 481-488.
39. Park, M.K., Belluzzi, J.D., Han, S.H., Cao, J., Leslie, F.M., 2007. Age, sex and early environment contribute to individual differences in nicotine/acetaldehyde-induced behavioral and endocrine responses in rats. Pharmacol. Biochem. Behav. 86, 297-305.
40. Paxinos, G., Watson, C., 1986. The rat brain in stereotaxic coordinates. New York.
41. Pontieri, F.E., Tanda, G., Orzi, F., Di Chiara, G., 1996. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 382, 255-257. (Pubitemid 26251360)
42. Rezvani, A.H., Caldwell, D.P., Levin, E.D., 2005. Nicotinic-serotonergic drug interactions and attentional performance in rats. Psychopharmacology (Berl) 179, 521-528. (Pubitemid 40674752)
43. Richardson, N.R., Roberts, D.C., 1996. Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy. J. Neurosci. Methods 66, 1-11. (Pubitemid 26180064)
44. Rose, J.E., Behm, F.M., Westman, E.C., Johnson, M., 2000. Dissociating nicotine and nonnicotine components of cigarette smoking. Pharmacol. Biochem. Behav. 67, 71-81.
45. Smith, D.F., 1980. Lithium and motor activity of animals: effects and possible mechanism of action. Int. Pharmacopsychiatry 15, 197-217. (Pubitemid 11087421)
46. Villégier, A.S., Blanc, G., Glowinski, J., Tassin, J.P., 2003. Transient behavioral sensitization to nicotine becomes long-lasting with monoamine oxidases inhibitors. Pharmacol. Biochem. Behav. 76, 267-274.
47. Villégier, A.S., Salomon, L., Blanc, G., Godeheu, G., Glowinski, J., Tassin, J.P., 2006a. Irreversible blockade of monoamine oxidases reveals the critical role of 5-HT transmission in locomotor response induced by nicotine in mice. Eur. J. Neurosci. 24, 1359-1365.
48. Villégier, A.S., Salomon, L., Granon, S., Changeux, J.P., Belluzzi, J.D., Leslie, F.M., Tassin, J.P., 2006b. Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. Neuropsychopharmacology 31, 1704-1713. (Pubitemid 44106701)
49. Villégier, A.S., Lotfipour, S., Belluzzi, J.D., Leslie, F.M., 2007a. Involvement of alpha1-adrenergic receptors in tranylcypromine enhancement of nicotine self-administration in rat. Psychopharmacology (Berl) 193, 457-465. (Pubitemid 47094374)
50. Villégier, A.S., Lotfipour, S., McQuown, S.C., Belluzzi, J.D., Leslie, F.M., 2007b. Tranylcypromine enhancement of nicotine self-administration. Neuropharmacology 52, 1415-1425. (Pubitemid 46601533)
51. Villégier, A.S., Belluzzi, J.D., Leslie, F.M., 2010. Serotonergic mechanism underlying tranylcypromine enhancement of nicotine self-administration. Synapse.
52. Wooters, T.E., Bardo, M.T., 2007. The monoamine oxidase inhibitor phenelzine enhances the discriminative stimulus effect of nicotine in rats. Behav. Pharmacol. 18, 601-608.
53. Yoshimura, R.F., Hogenkamp, D.J., Li,W.Y., Tran, M.B., Belluzzi, J.D., Whittemore, E.R., Leslie, F.M., Gee, K.W., 2007. Negative allosteric modulation of nicotinic acetylcholine receptors blocks nicotine self-administration in rats. J. Pharmacol. Exp. Ther. 323, 907-915.
54. Zhang, W., Kilicarslan, T., Tyndale, R.F., Sellers, E.M., 2001. Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro. Drug Metab. Dispos. 29, 897-902.