Oncostatin M-enhanced vascular endothelial growth factor expression in human vascular smooth muscle cells involves PI3K-, p38 MAPK-, Erk1/2- and STAT1/STAT3-dependent pathways and is attenuated by interferon-γ

Basic Research in Cardiology

Volumn 106, Issue 2, 2011, Pages 217-231

  Demyanets, Svitlana ^a   Kaun, Christoph ^a   Rychli, Kathrin ^a   Pfaffenberger, Stefan ^a   Kastl, Stefan P ^a,c   Hohensinner, Philipp J ^a   Rega, Gersina ^a   Katsaros, Katharina M ^a,c   Afonyushkin, Taras ^a   Bochkov, Valery N ^a   Paireder, Matthias ^a   Huk, Igor ^a   Maurer, Gerald ^a   Huber, Kurt ^b   Wojta, Johann ^a,c  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b WILHELMINEN HOSPITAL   (Austria)

^c Ludwig Boltzmann Cluster for Cardiovascular Research   (Austria)

Author keywords

Glycoprotein 130; Oncostatin M; Smooth muscle cells; Vascular endothelial growth factor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (4 HYDROXYPHENYL) 4 MORPHOLINOPYRIDO[3',2':4,5]FURO[3,2 D]PYRIMIDINE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BIRB 0796; GAMMA INTERFERON; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; ONCOSTATIN M; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN INHIBITOR; STAT1 PROTEIN; STAT3 PROTEIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VASCULOTROPIN; WP 1066; IL10 PROTEIN, HUMAN; IL4 PROTEIN, HUMAN; INTERLEUKIN 10; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE P38; STAT1 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CONTROLLED STUDY; CORONARY ARTERY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RNA ANALYSIS; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; CELL CULTURE; CORONARY BLOOD VESSEL; METABOLISM; SIGNAL TRANSDUCTION; UPREGULATION;

ADULT; AGED; ATHEROSCLEROSIS; CELLS, CULTURED; CORONARY VESSELS; FEMALE; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-4; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; ONCOSTATIN M; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; RNA, MESSENGER; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79957852734     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-010-0141-0     Document Type: Article

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