Interferon-γ-secreting NK cells promote induction of dry eye disease

Journal of Leukocyte Biology

Volumn 89, Issue 6, 2011, Pages 965-972

  Chen, Yihe ^a   Chauhan, Sunil K ^a   Saban, Daniel R ^a   Sadrai, Zahra ^a   Okanobo, Andre ^a   Dana, Reza ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

Antigen presenting cells; Immunopathogenesis; Ocular surface

Indexed keywords

GAMMA INTERFERON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CELL MATURATION; CELL SECRETION; CONJUNCTIVA; DISEASE SEVERITY; DRY EYE; FEMALE; IN VIVO STUDY; LYMPHOID TISSUE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; ANTIGEN-PRESENTING CELLS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DRY EYE SYNDROMES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; IMMUNOENZYME TECHNIQUES; INTERFERON-GAMMA; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MUS;

EID: 79957844124     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1110611     Document Type: Article

References (34)

1. Schaumberg, D. A., Sullivan, D. A., Buring, J. E., Dana, M. R. (2003) Prevalence of dry eye syndrome among US women. Am. J. Ophthalmol. 136, 318-326.
2. Schaumberg, D. A., Dana, R., Buring, J. E., Sullivan, D. A. (2009) Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies. Arch. Ophthalmol. 127, 763-768.
3. Solomon, A., Dursun, D., Liu, Z., Xie, Y., Macri, A., Pflugfelder, S. C. (2001) Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease. Invest. Ophthalmol. Vis. Sci. 42, 2283-2292.
4. Massingale, M. L., Li, X., Vallabhajosyula, M., Chen, D., Wei, Y., Asbell, P. A. (2009) Analysis of inflammatory cytokines in the tears of dry eye patients. Cornea 28, 1023-1027.
5. Enriquez-de-Salamanca, A., Castellanos, E., Stern, M. E., Fernandez, I., Carreno, E., Garcia-Vazquez, C., Herreras, J. M., Calonge, M. (2010) Tear cytokine and chemokine analysis and clinical correlations in evaporative-type dry eye disease. Mol. Vis. 16, 862-873.
6. de Paiva, C. S., Chotikavanich, S., Pangelinan, S. B., Pitcher, J. D., Fang, B., Zheng, X., Ma, P., Farley, W. J., Siemasko, K. F., Niederkorn, J. Y., Stern, M. E., Li, D. Q., Pflugfelder, S. C. (2009) IL-17 disrupts corneal barrier following desiccating stress. Mucosal Immunol. 2, 243-253.
7. Stern, M. E., Gao, J., Schwalb, T. A., Ngo, M., Tieu, D. D., Chan, C. C., Reis, B. L., Whitcup, S. M., Thompson, D., Smith, J. A. (2002) Conjuncti-val T cell subpopulations in Sjogren's and non-Sjogren's patients with dry eye. Invest. Ophthalmol. Vis. Sci. 43, 2609-2614.
8. Niederkorn, J. Y., Stern, M. E., Pflugfelder, S. C., De Paiva, C. S., Cor-rales, R. M., Gao, J., Siemasko, K. (2006) Desiccating stress induces T cell-mediated Sjogren's syndrome-like lacrimal keratoconjunctivitis. J. Immunol. 176, 3950-3957.
9. El Annan, J., Chauhan, S. K., Ecoiffier, T., Zhang, Q., Saban, D. R., Dana, R. (2009) Characterization of effector T cells in dry eye disease. Invest. Ophthalmol. Vis. Sci. 50, 3802-3807.
10. Chauhan, S. K., El Annan, J., Ecoiffier, T., Goyal, S., Zhang, Q., Saban, D. R., Dana, R. (2009) Autoimmunity in dry eye is due to resistance of Th17 to Treg suppression. J. Immunol. 182, 1247-1252.
11. Andoniou, C. E., Coudert, J. D., Degli-Esposti, M. A. (2008) Killers and beyond: NK-cell-mediated control of immune responses. Eur. J. Immunol. 38, 2938-2942.
12. Winkler-Pickett, R., Young, H. A., Cherry, J. M., Diehl, J., Wine, J., Back, T., Bere, W. E., Mason, A. T., Ortaldo, J. R. (2008) In vivo regulation of experimental autoimmune encephalomyelitis by NK cells: alteration of primary adaptive responses. J. Immunol. 180, 4495-4506.
13. Shi, F. D., Wang, H. B., Li, H., Hong, S., Taniguchi, M., Link, H., Van Kaer, L., Ljunggren, H. G. (2000) Natural killer cells determine the outcome of B cell-mediated autoimmunity. Nat. Immunol. 1, 245-251.
14. Poirot, L., Benoist, C., Mathis, D. (2004) Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity. Proc. Natl. Acad. Sci. USA 101, 8102-8107.
15. Takeda, K., Dennert, G. (1993) The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms. J. Exp. Med. 177, 155-164.
16. Zhang, B., Yamamura, T., Kondo, T., Fujiwara, M., Tabira, T. (1997) Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells. J. Exp. Med. 186, 1677-1687.
17. Xu, W., Fazekas, G., Hara, H., Tabira, T. (2005) Mechanism of natural killer (NK) cell regulatory role in experimental autoimmune encephalo-myelitis. J. Neuroimmunol. 163, 24-30.
18. Lee, I. F., Qin, H., Trudeau, J., Dutz, J., Tan, R. (2004) Regulation of autoimmune diabetes by complete Freund's adjuvant is mediated by NK cells. J. Immunol. 172, 937-942.
19. Barabino, S., Shen, L., Chen, L., Rashid, S., Rolando, M., Dana, M. R. (2005) The controlled-environment chamber: a new mouse model of dry eye. Invest. Ophthalmol. Vis. Sci. 46, 2766-2771.
20. Goyal, S., Chauhan, S. K, Zhang, Q., Dana, R (2009) Amelioration of murine dry eye disease by topical antagonist to chemokine receptor 2. Arch. Ophthalmol. 127, 882-887.
21. Lemp, M. A. (1995) Report of the National Eye Institute/Industry workshop on clinical trials in dry eyes. CLAO J. 21, 221-232.
22. Shi, Y., Ling, B., Zhou, Y., Gao, T., Feng, D., Xiao, M., Feng, L. (2007) Interferon-7 expression in natural killer cells and natural killer T cells is suppressed in early pregnancy. Cell. Mol. Immunol. 4, 389-394.
23. Rashid, S., Jin, Y., Ecoiffier, T., Barabino, S., Schaumberg, D. A., Dana, M. R (2008) Topical to-3 and to-6 fatty acids for treatment of dry eye. Arch. Ophthalmol. 126, 219-225.
24. Ecoiffier, T., El Annan, J., Rashid, S., Schaumberg, D., Dana, R (2008) Modulation of integrin a4/31 (VLA-4) in dry eye disease. Arch. Ophthalmol. 126, 1695-1699.
25. de Paiva, C. S., Villarreal, A. L., Corrales, R M., Rahman, H. T., Chang, V. Y, Farley, W. J., Stern, M. E., Niederkorn, J. Y, Li, D. Q., Pflugfelder, S. C. (2007) Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-7. Invest. Ophthalmol. Vis. Sci. 48, 2553-2560.
26. Albertsmeyer, A. C, Kakkassery, V., Spurr-Michaud, S., Beeks, O., Gipson, I. K. (2010) Effect of pro-inflammatory mediators on membrane-associated mucins expressed by human ocular surface epithelial cells. Exp. Eye Res. 90, 444-451.
27. Shi, F. D., Van Kaer, L. (2006) Reciprocal regulation between natural killer cells and autoreactive T cells. Nat. Rev. Immunol. 6, 751-760.
28. Ehl, S., Nuesch, R., Tanaka, T., Myasaka, M., Hengartner, H., Zinkerna-gel, R. (1996) A comparison of efficacy and specificity of three NK depleting antibodies. J. Immunol. Methods 199, 149-153.
29. Godfrey, D. I., Hammond, K. J. L., Poulton, L. D., Smyth, M. J., Baxter, A. G. (2000) NKT cells: facts, functions and fallacies. Immunol. Today 21, 573-583.
30. Luo, L., Li, D. Q., Doshi, A., Farley, W., Corrales, R. M., Pflugfelder, S. C. (2004) Experimental dry eye stimulates production of inflammatory cyto-kines and MMP-9 and activates MAPK signaling pathways on the ocular surface. Invest. Ophthalmol. Vis. Sci. 45, 4293-4301.
31. Huq, S., Liu, Y., Benichou, G., Dana, M. R. (2004) Relevance of the direct pathway of sensitization in corneal transplantation is dictated by the graft bed microenvironment. J. Immunol. 173, 4464-4469.
32. Chauhan, S. K., Dana, R. (2009) Role of Th17 cells in the immunopatho-genesis of dry eye disease. Mucosal Immunol. 2, 375-376.
33. Degli-Esposti, M. A., Smyth, M. J. (2005) Close encounters of different kinds: dendritic cells and NK cells take center stage. Nat. Rev. Immunol. 5, 112-124.
34. Piccioli, D., Sbrana, S., Melandri, E., Valiante, N. M. (2002) Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells. J. Exp. Med. 195, 335-341.