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Volumn 16, Issue 2, 2011, Pages

Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: Possible pathways of action

Author keywords

Apoptosis; Autophagy; Immune system; Photodynamic therapy; Rats

Indexed keywords

APOPTOTIC; AUTOPHAGY; BIOINFORMATICS ANALYSIS; BLADDER CANCERS; CANCER STEM CELLS; CASPASE-3; GENE EXPRESSION PROFILES; HUMAN BLADDER CANCER; IMMUNE SYSTEMS; IMMUNOHISTOCHEMISTRY; MITOCHONDRIAL APOPTOSIS; MITOCHONDRIAL DAMAGE; MONONUCLEAR CELLS; ORTHOTOPIC; PHOTODYNAMIC TREATMENTS; PROLIFERATING CELL NUCLEAR ANTIGENS; T CELL ACTIVATION; T-CELL RECEPTORS; TISSUE RESPONSE; TUMORIGENESIS; UROTHELIUM;

EID: 79957817378     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3536536     Document Type: Article
Times cited : (10)

References (49)
  • 1
    • 0036274925 scopus 로고    scopus 로고
    • Surgery and adjunctive chemotherapy for invasive bladder cancer
    • D. Raghavan, D. Quinn, D. G. Skinner, and J. P. Stein, "Surgery and adjunctive chemotherapy for invasive bladder cancer," Surg. Oncol. 11(1-2), 55-63 (2002).
    • (2002) Surg. Oncol. , vol.11 , Issue.1-2 , pp. 55-63
    • Raghavan, D.1    Quinn, D.2    Skinner, D.G.3    Stein, J.P.4
  • 2
    • 0029042453 scopus 로고
    • The relationship among multiple recurrences, progression and prognosis of patients with stages ta and T1 transitional cell cancer of the bladder followed for at least 20 years
    • discussion 1826-1827
    • S. Holmang, H. Hedelin, C. Anderstrom, and S. L. Johansson, "The relationship among multiple recurrences, progression and prognosis of patients with stages Ta and T1 transitional cell cancer of the bladder followed for at least 20 years," J. Urol. 153(6), 1823-1826; discussion 1826-1827 (1995).
    • (1995) J. Urol. , vol.153 , Issue.6 , pp. 1823-1826
    • Holmang, S.1    Hedelin, H.2    Anderstrom, C.3    Johansson, S.L.4
  • 6
    • 0033562695 scopus 로고    scopus 로고
    • BCG immunotherapy of bladder cancer: 20 years on
    • A. B. Alexandroff, A. M. Jackson, M. A. O'Donnell, and K. James, "BCG immunotherapy of bladder cancer: 20 years on," Lancet 353(9165), 1689-1694 (1999).
    • (1999) Lancet , vol.353 , Issue.9165 , pp. 1689-1694
    • Alexandroff, A.B.1    Jackson, A.M.2    O'Donnell, M.A.3    James, K.4
  • 7
    • 4344607063 scopus 로고    scopus 로고
    • Role of urothelial cells in BCG immunotherapy for superficial bladder cancer
    • R. F. Bevers, K. H. Kurth, and D. H. Schamhart, "Role of urothelial cells in BCG immunotherapy for superficial bladder cancer," Br. J. Cancer 91(4), 607-612 (2004).
    • (2004) Br. J. Cancer , vol.91 , Issue.4 , pp. 607-612
    • Bevers, R.F.1    Kurth, K.H.2    Schamhart, D.H.3
  • 8
    • 76649112386 scopus 로고    scopus 로고
    • Emerging targeted therapies for bladder cancer: A disease waiting for a drug
    • S. J. Dovedi and B. R. Davies, "Emerging targeted therapies for bladder cancer: a disease waiting for a drug," Cancer Metastasis Rev. 28(3-4), 355-367 (2009).
    • (2009) Cancer Metastasis Rev , vol.28 , Issue.3-4 , pp. 355-367
    • Dovedi, S.J.1    Davies, B.R.2
  • 10
    • 0026458742 scopus 로고
    • Complications of intravesical bacillus calmette-guerin: A case report
    • J. A. Gonzalez, B. R. Marcol, and M. C. Wolf, "Complications of intravesical bacillus Calmette-Guerin: a case report," J. Urol. 148(6), 1892-1893 (1992).
    • (1992) J. Urol. , vol.148 , Issue.6 , pp. 1892-1893
    • Gonzalez, J.A.1    Marcol, B.R.2    Wolf, M.C.3
  • 11
    • 0029940618 scopus 로고    scopus 로고
    • Granulomatous hepatitis caused by bacillus calmette-guerin (BCG) infection after BCG bladder instillation
    • F. W. Leebeek, R. J. Ouwendijk, A. H. Kolk, A. Dees, J. C. Meek, J. E. Nienhuis, and A. M. Dingemans-Dumas, "Granulomatous hepatitis caused by Bacillus Calmette-Guerin (BCG) infection after BCG bladder instillation," Gut 38(4), 616-618 (1996).
    • (1996) Gut , vol.38 , Issue.4 , pp. 616-618
    • Leebeek, F.W.1    Ouwendijk, R.J.2    Kolk, A.H.3    Dees, A.4    Meek, J.C.5    Nienhuis, J.E.6    Dingemans-Dumas, A.M.7
  • 12
    • 39649103641 scopus 로고    scopus 로고
    • Effect of advanced age on the development of complications from intravesical bacillus calmette-guerin therapy
    • J. G. Heiner and M. K. Terris, "Effect of advanced age on the development of complications from intravesical bacillus Calmette-Guerin therapy," Urol. Oncol. 26(2), 137-140 (2008).
    • (2008) Urol. Oncol. , vol.26 , Issue.2 , pp. 137-140
    • Heiner, J.G.1    Terris, M.K.2
  • 13
    • 34147105045 scopus 로고    scopus 로고
    • Clinically relevant reduction in risk of recurrence of superficial bladder cancer using 5-aminolevulinic acid-induced fluorescence diagnosis: 8-year results of prospective randomized study
    • S. Denzinger, M. Burger, B. Walter, R. Knuechel, W. Roessler, W. F. Wieland, and T. Filbeck, "Clinically relevant reduction in risk of recurrence of superficial bladder cancer using 5-aminolevulinic acid-induced fluorescence diagnosis: 8-year results of prospective randomized study," Urology 69(4), 675-679 (2007).
    • (2007) Urology , vol.69 , Issue.4 , pp. 675-679
    • Denzinger, S.1    Burger, M.2    Walter, B.3    Knuechel, R.4    Roessler, W.5    Wieland, W.F.6    Filbeck, T.7
  • 14
    • 77249090657 scopus 로고    scopus 로고
    • Photodynamic diagnosis in non-muscle-invasive bladder cancer: A systematic review and cumulative analysis of prospective studies
    • I. Kausch, M. Sommerauer, F. Montorsi, A. Stenzl, D. Jacqmin, P. Jichlinski, D. Jocham, A. Ziegler, and R. Vonthein, "Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies," Eur. Urol. 57(4), 595-606 (2009).
    • (2009) Eur. Urol. , vol.57 , Issue.4 , pp. 595-606
    • Kausch, I.1    Sommerauer, M.2    Montorsi, F.3    Stenzl, A.4    Jacqmin, D.5    Jichlinski, P.6    Jocham, D.7    Ziegler, A.8    Vonthein, R.9
  • 16
    • 70749144311 scopus 로고    scopus 로고
    • The role of photodynamic therapy in the esophagus
    • vi
    • S. A. Gross and H. C. Wolfsen, "The role of photodynamic therapy in the esophagus," Gastrointest. Endosc. Clin. N. Am. 20(1), 35-53, vi (2010).
    • (2010) Gastrointest. Endosc. Clin. N. Am. , vol.20 , Issue.1 , pp. 35-53
    • Gross, S.A.1    Wolfsen, H.C.2
  • 17
    • 40349108416 scopus 로고    scopus 로고
    • Brain photodiagnosis (PD), fluorescence guided resection (FGR) and photodynamic therapy (PDT): Past, present and future
    • M. S. Eljamel, "Brain photodiagnosis (PD), fluorescence guided resection (FGR) and photodynamic therapy (PDT): past, present and future," Photodiagnos. Photodyn. Ther. 5(1), 29-35 (2008).
    • (2008) Photodiagnos. Photodyn. Ther. , vol.5 , Issue.1 , pp. 29-35
    • Eljamel, M.S.1
  • 21
    • 52449106213 scopus 로고    scopus 로고
    • Combination of photodynamic therapy with anti-cancer agents
    • M. F. Zuluaga and N. Lange, "Combination of photodynamic therapy with anti-cancer agents," Curr. Med. Chem. 15(17), 1655-1673 (2008).
    • (2008) Curr. Med. Chem. , vol.15 , Issue.17 , pp. 1655-1673
    • Zuluaga, M.F.1    Lange, N.2
  • 22
    • 33745699944 scopus 로고    scopus 로고
    • Photodynamic therapy and anti-tumor immunity
    • S. O. Gollnick, B. Owczarczak, and P. Maier, "Photodynamic therapy and anti-tumor immunity," Lasers Surg. Med. 38(5), 509-515 (2006).
    • (2006) Lasers Surg. Med. , vol.38 , Issue.5 , pp. 509-515
    • Gollnick, S.O.1    Owczarczak, B.2    Maier, P.3
  • 23
    • 0033561534 scopus 로고    scopus 로고
    • Photodynamic therapy-mediated immune response against subcutaneous mouse tumors
    • M. Korbelik and G. J. Dougherty, "Photodynamic therapy-mediated immune response against subcutaneous mouse tumors," Cancer Res. 59(8), 1941-1946 (1999).
    • (1999) Cancer Res , vol.59 , Issue.8 , pp. 1941-1946
    • Korbelik, M.1    Dougherty, G.J.2
  • 25
    • 77649193095 scopus 로고    scopus 로고
    • Gene expression profiling and pathway analysisofsuperficial bladder cancer in rats
    • C. J. Arum, E. Anderssen, K. Tommeras, S. Lundgren, D. Chen, and C. M. Zhao, "Gene expression profiling and pathway analysisofsuperficial bladder cancer in rats," Urology 75(3), 742-749 (2010).
    • (2010) Urology , vol.75 , Issue.3 , pp. 742-749
    • Arum, C.J.1    Anderssen, E.2    Tommeras, K.3    Lundgren, S.4    Chen, D.5    Zhao, C.M.6
  • 27
    • 5444250504 scopus 로고    scopus 로고
    • Kinetics, biodistribution and therapeutic efficacy of hexylester 5-aminolevulinate induced photodynamic therapy in an or-thotopic rat bladder tumor model
    • S. El Khatib, J. Didelon, A. Leroux, L. Bezdetnaya, D. Notter, and M. D'Hallewin, "Kinetics, biodistribution and therapeutic efficacy of hexylester 5-aminolevulinate induced photodynamic therapy in an or-thotopic rat bladder tumor model," J. Urol. 172(5 Pt 1), 2013-2017 (2004).
    • (2004) J. Urol. , vol.172 , Issue.5 PART 1 , pp. 2013-2017
    • El Khatib, S.1    Didelon, J.2    Leroux, A.3    Bezdetnaya, L.4    Notter, D.5    D'Hallewin, M.6
  • 28
    • 75549090213 scopus 로고    scopus 로고
    • KEGG for representation and analysis of molecular networks involving diseases and drugs
    • M. Kanehisa, S. Goto, M. Furumichi, M. Tanabe, M. Hirakawa, "KEGG for representation and analysis of molecular networks involving diseases and drugs," Nucl. Acids Res. 38 (Suppl. 1), D355-60 (2010)
    • (2010) Nucl. Acids Res. , vol.38 , Issue.SUPPL. 1
    • Kanehisa, M.1    Goto, S.2    Furumichi, M.3    Tanabe, M.4    Hirakawa, M.5
  • 29
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto encyclopaedia of genes and genomes
    • M. Kanehisa, S. Goto, "KEGG: Kyoto Encyclopaedia of Genes and Genomes," Nucl. Acids Res. 28(1), 27-30 (2000).
    • (2000) Nucl. Acids Res. , vol.28 , Issue.1 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 30
    • 77953177649 scopus 로고    scopus 로고
    • Cancer immunoediting from immunosurveillance to tumor escape in microvillus-formed niche: A study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer
    • C. J. Arum, E. Anderssen, T. Viset, Y. Kodama, S. Lundgren, D. Chen, and C. M. Zhao, "Cancer immunoediting from immunosurveillance to tumor escape in microvillus-formed niche: a study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer," Neoplasia 12(6), 434-442 (2010).
    • (2010) Neoplasia , vol.12 , Issue.6 , pp. 434-442
    • Arum, C.J.1    Anderssen, E.2    Viset, T.3    Kodama, Y.4    Lundgren, S.5    Chen, D.6    Zhao, C.M.7
  • 31
    • 0029155802 scopus 로고
    • Epithelial tumours of the lower urinary tract in humans and rodents
    • R. Oyasu, "Epithelial tumours of the lower urinary tract in humans and rodents," Food Chem. Toxicol. 33(9), 747-755 (1995).
    • (1995) Food Chem. Toxicol. , vol.33 , Issue.9 , pp. 747-755
    • Oyasu, R.1
  • 32
    • 33646019838 scopus 로고    scopus 로고
    • Experimental bladder carcinogenesis-rodent models
    • P. A. Oliveira, A. Colaco, P. L. De la Cruz, and C. Lopes, "Experimental bladder carcinogenesis-rodent models," Exp. Oncol. 28(1), 2-11 (2006).
    • (2006) Exp. Oncol , vol.28 , Issue.1 , pp. 2-11
    • Oliveira, P.A.1    Colaco, A.2    De La Cruz, P.L.3    Lopes, C.4
  • 33
    • 0345407181 scopus 로고    scopus 로고
    • Photodetection of early human bladder cancer based on the fluorescence of 5-aminolaevulinic acid hexylester-induced protoporphyrin IX: A pilot study
    • N. Lange, P. Jichlinski, M. Zellweger, M. Forrer, A. Marti, L. Guillou, P. Kucera, G. Wagnieres, and H. Van Den Bergh, "Photodetection of early human bladder cancer based on the fluorescence of 5-aminolaevulinic acid hexylester-induced protoporphyrin IX: a pilot study," Br. J. Cancer 80(1-2), 185-193 (1999).
    • (1999) Br. J. Cancer , vol.80 , Issue.1-2 , pp. 185-193
    • Lange, N.1    Jichlinski, P.2    Zellweger, M.3    Forrer, M.4    Marti, A.5    Guillou, L.6    Kucera, P.7    Wagnieres, G.8    Van Den Bergh, H.9
  • 34
    • 39649116444 scopus 로고    scopus 로고
    • Pharmacokinetics and selectivity of porphyrin synthesis after topical application of hexaminolevulinate in patients with cervical intraepithelial neoplasia
    • P. Hillemanns, X. Wang, H. Hertel, V. Andikyan, M. Hillemanns, H. Stepp, and P. Soergel, "Pharmacokinetics and selectivity of porphyrin synthesis after topical application of hexaminolevulinate in patients with cervical intraepithelial neoplasia," Am. J. Obstet. Gynecol. 198(3), 300.e1-300.e7 (2008).
    • (2008) Am. J. Obstet. Gynecol. , vol.198 , Issue.3
    • Hillemanns, P.1    Wang, X.2    Hertel, H.3    Andikyan, V.4    Hillemanns, M.5    Stepp, H.6    Soergel, P.7
  • 35
    • 0033919071 scopus 로고    scopus 로고
    • The morphological changes in rat bladder after photodynamic therapy with 5-aminolaevulinic acid-induced pro-toporphyrin IX
    • S. Gronlund-Pakkanen, T. M. Pakkanen, M. Talja, V. M. Kosma, M. Ala-Opas. and E. Alhava, "The morphological changes in rat bladder after photodynamic therapy with 5-aminolaevulinic acid-induced pro-toporphyrin IX," BJU Int. 86(1), 126-132 (2000).
    • (2000) BJU Int , vol.86 , Issue.1 , pp. 126-132
    • Gronlund-Pakkanen, S.1    Pakkanen, T.M.2    Talja, M.3    Kosma, V.M.4    Ala-Opas, M.5    Alhava, E.6
  • 36
    • 33745714000 scopus 로고    scopus 로고
    • Targeted photodynamic therapy
    • N. Solban, I. Rizvi, and T. Hasan, "Targeted photodynamic therapy," Lasers Surg. Med. 38(5), 522-531 (2006).
    • (2006) Lasers Surg. Med. , vol.38 , Issue.5 , pp. 522-531
    • Solban, N.1    Rizvi, I.2    Hasan, T.3
  • 37
    • 33745537921 scopus 로고    scopus 로고
    • Photodynamic therapy and anti-tumour immunity
    • A. P. Castano, P. Mroz, and M. R. Hamblin, "Photodynamic therapy and anti-tumour immunity," Nat. Rev. Cancer 6(7), 535-545 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.7 , pp. 535-545
    • Castano, A.P.1    Mroz, P.2    Hamblin, M.R.3
  • 38
    • 34249941838 scopus 로고    scopus 로고
    • Mitochondria are targets of photodynamic therapy
    • R. Hilf, "Mitochondria are targets of photodynamic therapy," J. Bioenerg. Biomembr. 39(1), 85-89 (2007).
    • (2007) J. Bioenerg. Biomembr. , vol.39 , Issue.1 , pp. 85-89
    • Hilf, R.1
  • 39
    • 36549035313 scopus 로고    scopus 로고
    • Lipofuscin: Formation, distribution, and metabolic consequences
    • T. Jung, N. Bader, and T. Grune, "Lipofuscin: formation, distribution, and metabolic consequences," Ann. N.Y. Acad. Sci. 1119, 97-111 (2007).
    • (2007) Ann. N.Y. Acad. Sci. , vol.1119 , pp. 97-111
    • Jung, T.1    Bader, N.2    Grune, T.3
  • 40
    • 80455146303 scopus 로고    scopus 로고
    • Quinolone compounds enhance {delta}-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin IX and photosensitiv-ity of tumor cells
    • Y. Ohgari, Y. Miyata, T. Thanh Chau, S. Kitajima, Y. Adachi, and S. Taketani, "Quinolone compounds enhance {delta}-aminolevulinic acid (ALA)-induced accumulation of protoporphyrin IX and photosensitiv-ity of tumor cells," J. Biochem. (2010).
    • (2010) J. Biochem.
    • Ohgari, Y.1    Miyata, Y.2    Thanh Chau, T.3    Kitajima, S.4    Adachi, Y.5    Taketani, S.6
  • 41
    • 33745727948 scopus 로고    scopus 로고
    • Initiation of apoptosis and autophagy by photodynamic therapy
    • D. Kessel, M. G. Vicente, and J. J. Reiners, Jr., "Initiation of apoptosis and autophagy by photodynamic therapy," Lasers Surg. Med. 38(5), 482-488 (2006).
    • (2006) Lasers Surg. Med. , vol.38 , Issue.5 , pp. 482-488
    • Kessel, D.1    Vicente, M.G.2    Reiners Jr., J.J.3
  • 42
    • 34548758565 scopus 로고    scopus 로고
    • Apoptosis and autophagy after mito-chondrial or endoplasmic reticulum photodamage
    • D. Kessel and J. J. Reiners, Jr., "Apoptosis and autophagy after mito-chondrial or endoplasmic reticulum photodamage," Photochem. Pho-tobiol. 83(5), 1024-1028 (2007).
    • (2007) Photochem. Photobiol. , vol.83 , Issue.5 , pp. 1024-1028
    • Kessel, D.1    Reiners Jr., J.J.2
  • 43
    • 59649099979 scopus 로고    scopus 로고
    • Initiation ofautophagy by photodynamic therapy
    • D. Kessel and N. L. Oleinick, "Initiation ofautophagy by photodynamic therapy," Methods Enzymol. 453, 1-16 (2009).
    • (2009) Methods Enzymol , vol.453 , pp. 1-16
    • Kessel, D.1    Oleinick, N.L.2
  • 44
    • 0036837453 scopus 로고    scopus 로고
    • Intravesical bacillus calmette-guerin reduces the risk of progression in patients with superficial bladder cancer: A meta-analysis of the published results of randomized clinical trials
    • R. J. Sylvester, A.P.M. van der Meijden, and D. L. Lamm, "Intravesical bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: a meta-analysis of the published results of randomized clinical trials," J. Urol. 168(5), 1964-1970 (2002).
    • (2002) J. Urol. , vol.168 , Issue.5 , pp. 1964-1970
    • Sylvester, R.J.1    Van Der Meijden, A.P.M.2    Lamm, D.L.3
  • 45
    • 33744513525 scopus 로고    scopus 로고
    • Can intravesical bacillus calmette-guerin reduce recurrence in patients with superficial bladder cancer? A meta-analysis of randomized trials
    • R. F. Han and J. G. Pan, "Can intravesical bacillus Calmette-Guerin reduce recurrence in patients with superficial bladder cancer? A meta-analysis of randomized trials," Urology 67(6), 1216-1223 (2006).
    • (2006) Urology , vol.67 , Issue.6 , pp. 1216-1223
    • Han, R.F.1    Pan, J.G.2
  • 46
    • 67649431728 scopus 로고    scopus 로고
    • An individual patient data meta-analysis of the long-term outcome of randomised studies comparing intravesical mitomycin c versus bacillus calmette-guerin for non-muscle-invasive bladder cancer
    • Re: Per-Uno Malmstrom, Richard J. Sylvester, David E. Crawford, P-U. Malmstom, R.J. Sylvester, D.E. Crawford, M. Friedrich, S. Krege, E. Rintala, E. Solsona, S.M. Di Stasi, J. A. Witjes
    • D. Lamm, A. Bohle, J. Palou, R. Persad, M. Brausi, M. Colombel, H. Akaza, and R. Buckley, Re: Per-Uno Malmstrom, Richard J. Sylvester, David E. Crawford, P-U. Malmstom, R.J. Sylvester, D.E. Crawford, M. Friedrich, S. Krege, E. Rintala, E. Solsona, S.M. Di Stasi, J. A. Witjes, "An individual patient data meta-analysis of the long-term outcome of randomised studies comparing intravesical mitomycin c versus bacillus calmette-guerin for non-muscle-invasive bladder cancer" Eur. Urol. 56, 247-256 (2009)
    • (2009) Eur. Urol. , vol.56 , pp. 247-256
    • Lamm, D.1    Bohle, A.2    Palou, J.3    Persad, R.4    Brausi, M.5    Colombel, M.6    Akaza, H.7    Buckley, R.8
  • 47
    • 80455131658 scopus 로고    scopus 로고
    • author reply e10-11
    • Eur. Urol. 57(2), e7-9; author reply e10-11 (2010).
    • (2010) Eur. Urol. , vol.57 , Issue.2
  • 48
    • 42749084834 scopus 로고    scopus 로고
    • Photodynamic diagnosis in urology: State-of-the-art
    • D. Jocham, H. Stepp, and R. Waidelich, "Photodynamic diagnosis in urology: state-of-the-art," Eur. Urol. 53(6), 1138-1148 (2008).
    • (2008) Eur. Urol. , vol.53 , Issue.6 , pp. 1138-1148
    • Jocham, D.1    Stepp, H.2    Waidelich, R.3
  • 49
    • 63849286374 scopus 로고    scopus 로고
    • BCG versus photodynamic therapy (PDT) for nonmuscle invasive bladder cancer - A multicentre clinical phase III study
    • D. Jocham, J. von Wietersheim, H. Pfluger, H. Steiner, C. Doehn, H. Buttner, A. Bohle, and I. Kausch, "BCG versus photodynamic therapy (PDT) for nonmuscle invasive bladder cancer - a multicentre clinical phase III study," Aktuelle Urol. 40(2), 91-99 (2009).
    • (2009) Aktuelle Urol , vol.40 , Issue.2 , pp. 91-99
    • Jocham, D.1    Von Wietersheim, J.2    Pfluger, H.3    Steiner, H.4    Doehn, C.5    Buttner, H.6    Bohle, A.7    Kausch, I.8


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