Purification of functional baculovirus particles from silkworm larval hemolymph and their use as nanoparticles for the detection of human prorenin receptor (PRR) binding

BMC Biotechnology

Volumn 11, Issue , 2011, Pages

  Kato, Tatsuya ^a   Suzuki, Fumiaki ^b   Park, Enoch Y ^a  

^a SHIZUOKA UNIVERSITY   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

BmNPV human prorenin receptor; Display; ELISA; Silkworm

Indexed keywords

BACULOVIRUS; BOMBYX MORI NUCLEOPOLYHEDROVIRUS; DENSITOMETRY; DISPLAY; ELISA; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN PRORENIN; PROTEIN-PROTEIN INTERACTIONS; SILKWORM; TOTAL PROTEIN; TRANS-MEMBRANE DOMAINS; TRANS-MEMBRANE PROTEINS; TRITON X-100; WESTERN BLOTS;

ACTIVATION ANALYSIS; ANIMALS; BLOOD; COLUMN CHROMATOGRAPHY; DRUG INTERACTIONS; GENE ENCODING; PURIFICATION;

PROTEINS;

BETA 1,3 N ACETYLGLUCOSAMINYLTRANSFERASE 2; GREEN FLUORESCENT PROTEIN; N ACETYLGLUCOSAMINYLTRANSFERASE; NANOPARTICLE; PRORENIN; PRORENIN RECEPTOR; PROTEINASE K; TRITON X 100; UNCLASSIFIED DRUG; CELL SURFACE RECEPTOR; OCTOXINOL; RENIN;

ARTICLE; BACULOVIRUS; COLUMN CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); DENSITOMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMOLYMPH; NONHUMAN; POLYHEDROSIS VIRUS; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SILKWORM; SURFACE PROPERTY; VIRUS PURIFICATION; WESTERN BLOTTING; ANIMAL; CHEMISTRY; HUMAN; ISOLATION AND PURIFICATION; LARVA; METABOLISM; PROTEIN BINDING; VIRION; VIROLOGY;

BOMBYX MORI; BOMBYX MORI NPV;

ANIMALS; BOMBYX; ENDOPEPTIDASE K; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEMOLYMPH; HUMANS; LARVA; NANOPARTICLES; NUCLEOPOLYHEDROVIRUS; OCTOXYNOL; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RENIN; VIRION;

EID: 79957811707     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-11-60     Document Type: Article

References (40)

1. Ikonomou L, Schneider YJ, Agathos SN. Insect cell culture for industrial production of recombinant proteins. Appl Microbiol Biotechnol 2003, 62:1-20. 10.1007/s00253-003-1223-9, 12733003.
2. Kato T, Kajikawa M, Maenaka K, Park EY. Silkworm expression system as a platform technology in life science. Appl Microbiol Biotechnol 2009, 85:459-470.
3. Possee RD. Baculoviruses as expression vectors. Curr Opin Biotechnol 1997, 8:569-572. 10.1016/S0958-1669(97)80030-4, 9353228.
4. Harrap K. The structure of nucleopolyhedrosis viruses II. The virus particle. Virol 1972, 50:124-132.
5. Mäkela AR, Oker-Blom C. Baculovirus Display: A Multifunctional Technology for Gene Delivery and Eukaryotic Library Development. Adv Vir Res 2006, 68:91-112.
6. Toivola J, Gilbert L, Michel P, White D, Vuento M, Oker-Blom C. Disassembly of structurally modified viral nanoparticles: characterization by fluorescence correlation spectroscopy. C.R. Biologies 2005, 328:1052-1056. 10.1016/j.crvi.2005.08.006, 16314283.
7. Motohashi T, Shimojima T, Fukagawa T, Maenaka K, Park EY. Efficient large-scale protein production of larvae and pupae of silkworm by Bombyx mori nuclear polyhedrosis virus bacmid system. Biochem Biophys Res Commun 2005, 326:564-569. 10.1016/j.bbrc.2004.11.060, 15596136.
8. Kato T, Manoha SL, Tanaka S, Park EY. High-titer preparation of Bombyx mori nucleopolyhedrovirus (BmNPV) displaying recombinant protein in silkworm larvae by size exclusion chromatography and its characterization. BMC Biotechnol 2009, 9:55. 10.1186/1472-6750-9-55, 2703641, 19523201.
9. Ogata M, Nakajima M, Kato T, Obara T, Yagi H, Kato K, Usui T, Park EY. Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae. BMC Biotechnol 2009, 9:54. 10.1186/1472-6750-9-54, 19500344.
10. Gomi S, Majima K, Maeda S. Sequence analysis of the genome of Bombyx mori nucleopolyhedrovirus. J Gen Virol 1999, 80:1323-37.
11. He F, Madhan S, Kwang J. Baculovirus vector as a delivery vehicle for influenza vaccines. Expert Rev Vaccines 2009, 8:455-467. 10.1586/erv.09.2, 19348561.
12. Makela AR, Oker-Blom C. Baculovirus display: a multifunctional technology for gene delivery and eukaryotic library development. Adv Virus Res 2006, 68:91-112.
13. Grabherr R, Ernst W, Oker-Blom C, Jones I. Developments in the use of baculoviruses for the surface display of complex eukaryotic proteins. Trends Biotechnol 2001, 19:231-236. 10.1016/S0167-7799(01)01610-9, 11356285.
14. Martyn JC, Cardin AJ, Wines BD, Cendron A, Li S, Mackenzie J, Powell M, Gowans EJ. Surface display of IgG Fc on baculovirus vectors enhances binding to antigen-presenting cells and cell lines expressing Fc receptors. Arch Virol 2009, 154:1129-38. 10.1007/s00705-009-0423-8, 19557497.
15. Loisel TP, Ansanay H, St-Onge S, Gay B, Boulanger P, Strosberg AD, Marullo S, Bouvier M. Recovery of homogeneous and functional beta 2-adrenergic receptors from extracellular baculovirus particles. Nat Biotechnol 1997, 15:1300-1304. 10.1038/nbt1197-1300, 9359116.
16. Sakihama T, Masuda K, Sato T, Doi T, Kodama T, Hamakubo T. Functional reconstitution of G-protein-coupled receptor-mediated adenylyl cyclase activation by a baculoviral co-display system. J Biotechnol 2008, 135:28-33. 10.1016/j.jbiotec.2008.02.022, 18403039.
17. Sakihama T, Sato T, Iwanari H, Kitamura T, Sakaguchi S, Kodama T, Hamakubo T. A simple detection method for low-affinity membrane protein interactions by baculoviral display. PLoS One 2008, 3:e4024. 10.1371/journal.pone.0004024, 2602974, 19107192.
18. Kukkonen SP, Airenne KJ, Marjomaki V, Laitinen OH, Lehtolainen P, Kankaanpaa P, Mahonen AJ, Raty JK, Nordlund HR, Oker-Blom C, et al. Baculovirus capsid display: a novel tool for transduction imaging. Mol Ther 2003, 8:853-862. 10.1016/j.ymthe.2003.07.009, 14599820.
19. Ichihara A, Hayashi M, Kaneshiro Y, Suzuki F, Nakagawa T, Tada Y, Koura Y, Nishiyama A, Okada H, Uddin MN, Nabi AH, Ishida Y, Inagami T, Saruta T. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin. J Clin Invest 2004, 114:1128-1135. 522242, 15489960.
20. Prescott G, Silversides DW, Reudelhuber TL. Tissue activity of circulating prorenin. Am J Hypertension 2002, 15:280-285.
21. Burcklé CA, Danser AHJ, Müller DN, Garrelds IM, Gasc JM, Popova E, Plehm R, Peters J, Bader M, Nguyen G. Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension 2006, 47:552-556.
22. Du D, Kato T, Nabi AH, Suzuki F, Park EY. Expression of functional human (pro)renin receptor in silkworm (Bombyx mori) larvae using BmMNPV bacmid. Biotechnol Appl Biochem 2008, 49:195-202. 10.1042/BA20070136, 17705788.
23. Du D, Kato T, Suzuki F, Park EY. Binding affinity of full-length and extracellular domains of recombinant human (pro)renin receptor to human renin when expressed in the fat body and hemolymph of silkworm larvae. J Biosci Bioeng 2009, 108:304-9. 10.1016/j.jbiosc.2009.04.018, 19716519.
24. Kato T, Park EY. Specific expression of GFPuv-beta1,3-N-acetylglucosaminyltransferase 2 fusion protein in fat body of Bombyx mori silkworm larvae using signal peptide. Biochem Biophys Res Commun 2007, 359:543-548. 10.1016/j.bbrc.2007.05.137, 17544364.
25. Kato T, Kageshima A, Suzuki F, Park EY. Expression and purification of human (pro)renin receptor in insect cells using baculovirus expression system. Protein Expr Purif 2008, 58:242-248. 10.1016/j.pep.2007.11.011, 18171623.
26. Masuda K, Itoh H, Sakihama T, Akiyama C, Takahashi K, Fukuda R, Yokomizo T, Shimizu T, Kodama T, Hamakubo T. A combinatorial G protein-coupled receptor reconstitution system on budded baculovirus. Evidence for Galpha and Galphao coupling to a human leukotriene B4 receptor. J Biol Chem 2003, 278:24552-24562. 10.1074/jbc.M302801200, 12721292.
27. Fukushima H, Mizutani M, Imamura K, Morino K, Kobayashi J, Okumura K, Tsumoto K, Yoshimura T. Development of a novel preparation method of recombinant proteoliposomes using baculovirus gene expression systems. J Biochem 2008, 144:763-770. 10.1093/jb/mvn125, 18836200.
28. Shi L, Sanyal G, Ni A, Luo Z, Doshna S, Wang B, Graham TL, Wang N, Volkin DB. Stabilization of human papillomavirus virus-like particles by non-ionic surfactants. J Pharm Sci 2005, 94:1538-1551. 10.1002/jps.20377, 15929070.
29. Kissmann J, Ausar SF, Foubert TR, Brock J, Switzer MH, Detzi EJ, Vedvick TS, Middaugh CR. Physical stabilization of Norwalk virus-like particles. J Pharm Sci 2008, 97:4208-4218. 10.1002/jps.21315, 18300304.
30. Peixoto C, Sousa MF, Silva AC, Carrondo MJ, Alves PM. Downstream processing of triple layered rotavirus like particles. J Biotechnol 2007, 127:452-461. 10.1016/j.jbiotec.2006.08.002, 16959354.
31. Chawla AS, Hinberg I, Blais P, Johnson D. Aggregation of insulin, containing surfactants, in contact with different materials. Diabetes 1985, 34:420-424. 10.2337/diabetes.34.5.420, 3886458.
32. Twardowski ZJ, Nolph KD, McGary TJ, Moore HL. Nature of insulin binding to plastic bags. Am J Hosp Pharm 1983, 40:579-582.
33. Jorio H, Tran R, Meghrous J, Bourget L, Kamen A. Analysis of baculovirus aggregates using flow cytometry. J Virol Methods 2006, 134:8-14. 10.1016/j.jviromet.2005.11.009, 16364459.
34. Transfiguracion J, Jorio H, Meghrous J, Jacob D, Kamen A. High yield purification of functional baculovirus vectors by size exclusion chromatography. J Virol Methods 2007, 142:21-28. 10.1016/j.jviromet.2007.01.002, 17306891.
35. Hosokawa M, Hama S, Mandai K, Okuda K, Takashima S, Tajiri H, Eguchi K, Heike Y. Preparation of purified, sterilized, and stable adenovirus vectors using albumin. J Virol Methods 2002, 103:191-199. 10.1016/S0166-0934(02)00028-9, 12008013.
36. Wright JF, Qu G, Tang C, Sommer JM. Recombinant adeno-associated virus: formulation challenges and strategies for a gene therapy vector. Curr Opin Drug Discov Devel 2003, 6:174-178.
37. Mottershead DG, Alfthan K, Ojala K, Takkinen K, Oker-Blom C. Baculoviral display of functional scFv and synthetic IgG-binding domains. Biochem Biophys Res Commun 2000, 275:84-90. 10.1006/bbrc.2000.3264, 10944446.
38. Ojala K, Mottershead DG, Suokko A, Oker-Blom C. Specific binding of baculoviruses displaying gp64 fusion proteins to mammalian cells. Biochem Biophys Res Commun 2001, 284:777-784. 10.1006/bbrc.2001.5048, 11396970.
39. Wang BZ, Liu W, Kang SM, Alam M, Huang C, Ye L, Sun Y, Li Y, Kothe DL, Pushko P, et al. Incorporation of high levels of chimeric human immunodeficiency virus envelope glycoproteins into virus-like particles. J Virol 2007, 81:10869-10878. 10.1128/JVI.00542-07, 2045522, 17670815.
40. Nabi AH, Kageshima A, Uddin MN, Nakagawa T, Park EY, Suzuki F. Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int J Mol Med 2006, 18:483-488.