Natural killer cell deficiencies in a consecutive series of children with herpetic encephalitis

International Journal of Immunopathology and Pharmacology

Volumn 24, Issue 1, 2011, Pages 231-238

  Almerigogna, F ^a   Fassio, F ^a   Giudizi, M G ^a   Biagiotti, R ^a   Manuelli, C ^a   Chiappini, E ^b   Galli, L ^b   Romagnani, S ^a   De Martino, Maurizio ^a,b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

CD16 polymorphism; Encephalitis; Herpes virus; NK deficiencies

Indexed keywords

ACICLOVIR; CD16 ANTIGEN; CEFTRIAXONE; CLONAZEPAM; COMPLEMENTARY DNA; DEXAMETHASONE; DIAZEPAM; GENTAMICIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN E; PHENOBARBITAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; FC RECEPTOR; FCGR3A PROTEIN, HUMAN;

ARTICLE; B LYMPHOCYTE; CELL POPULATION; CHILD; CIRCULATING TUMOR CELL; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOFLUOROMETRY; DISEASE COURSE; FEMALE; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; HERPES SIMPLEX ENCEPHALITIS; HUMAN; IMMUNOPATHOLOGY; INFANT; INFECTION SENSITIVITY; ITALY; LEUKOCYTE COUNT; LYMPHOCYTOPENIA; MALE; NATURAL KILLER CELL; NATURAL KILLER CELL DEFICIENCY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; T LYMPHOCYTE; AMINO ACID SUBSTITUTION; CD16A GENE; CELLULAR IMMUNODEFICIENCY; DNA POLYMORPHISM; GENE; GENE SEQUENCE; GENOTYPE; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HETEROZYGOSITY; HOSPITAL ADMISSION; IMMUNOGLOBULIN BLOOD LEVEL; LEUKOCYTE DIFFERENTIAL COUNT; LYMPHOCYTE SUBPOPULATION; NEWBORN; BLOOD; GENETICS; IMMUNOLOGY;

CHILD; CHILD, PRESCHOOL; ENCEPHALITIS, HERPES SIMPLEX; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULINS; INFANT; INFANT, NEWBORN; KILLER CELLS, NATURAL; LEUKOCYTE COUNT; LYMPHOCYTE SUBSETS; MALE; RECEPTORS, IGG;

EID: 79957804124     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201102400128     Document Type: Article

References (21)

1. Meningitis and Encephalitis Fact Sheet. Bethesda, MD 20892 NIH Publication No. 04-4840. Office of communications and Public Liaison. National Institute of Neurological Disorders and Stroke. National Institutes of Health.
2. Kennedy P. Viral encephalitis: causes, differential diagnosis, and management. J Neurol Neurosurg Psychiatry 2004; 75:10-15.
3. Biron CA, Natuk RJ, Welsh RM. Generation of large granular T lymphocytes in vivo during viral infection. J Immunol 1986; 136:2280-6. (Pubitemid 16122319)
4. Habu S, Shimanura K, Akamatsu K, Okumura K, Tamaoki N. Protective role of natural killer cells in tumor growth and viral infection in mice. Exp Cell Biol 1984; 52:40-3. (Pubitemid 14156191)
5. Biron CA, Byron KS, Sullivan JL. Severe herpesvirus infections in an adolescent without natural killer cells. N Engl J Med 1989; 320:1731-5. (Pubitemid 19163129)
6. Orange JS. Human natural killer cell deficiencies and susceptibility to infection. Microbes Infect 2002; 4:1545-58. (Pubitemid 36050824)
7. Orange JS. Human natural killer cell deficiencies. Curr Opin Allergy Clin Immunol 2006; 6:399-409. (Pubitemid 44714151)
8. Shearer WT, Rosenblatt HM, Gelman RS, Oyomopito R, Plaeger S, Stiehm ER, et al. Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol 2003; 112:973-80. (Pubitemid 37412068)
9. De Haas M, Koene HR, Kleijer M, et al. A triallelic Fc gamma receptor type IHA polymorphism influences the binding of human IgG by NK cell Fc gamma RIIIa. J Immunol 1996; 156:2948-55. (Pubitemid 126660643)
10. De Vries E, Koene HR, Vossen JM, et al. Identification of an unusual Fc gamma receptor IIIa (CD16) on natural killer cells in a patient with recurrent infections. Blood 1996; 88:3022-7. (Pubitemid 26357384)
11. Jawahar S, Moody C, Chan M, Finberg R, Geha R, Chatila T. Natural Killer (NK) cell deficiency associated with an epitope-deficient Fc receptor type IIIA (CD16-II). Clin Exp Immunol 1996; 103:408-13. (Pubitemid 26089945)
12. Etzioni A, Eidenschenk C, Katz R, Beck R, Casanova JL, Pollack S. Fatal varicella associated with selective natural killer cell deficiency. J Pediatr 2005; 146:423-5. (Pubitemid 40341757)
13. Sobel RA, Collins AB, Colvin RB, Bhan AK. The in situ cellular immune response in acute herpes simplex encephalitis. Am J Pathol 1986; 125:332-8. (Pubitemid 17194691)
14. Tonnesen E, Christensen NJ, Brinklov MM. Natural killer cell activity during cortisol and adrenaline infusion in healthy volunteers. Eur J Clin Invest 1987; 17:497-503. (Pubitemid 18063918)
15. Takeuchi T, Nakagawa T, Ikemoto T, et al. A novel mutation in the FcgammaRIIIA gene (CD16) results in active natural killer cells lacking CD16. Autoimmunity 1999; 3:265-71. (Pubitemid 30223873)
16. Anegon I, Cuturi MC, Trinchieri G, Perussia B. Interaction of Fc receptor (CD16) ligands induces transcription of interleukin 2 receptor (CD25) and lymphokine genes and expression of their products in human natural killer cells. J Exp Med 1988; 167:452-72. (Pubitemid 18073647)
17. Paolini R, Molfetta R, Piccoli M, Frati L, Santoni A. Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement. Proc Natl Acad Sci USA 2001; 98:9611-6. (Pubitemid 32769351)
18. Ortaldo JR, Mason AT, O'Shea JJ. Receptor-induced death in human natural killer cells: involvement of CD16. J Exp Med 1995; 181:339-44.
19. Casrouge A, Zhang SY, Eidenschenk C, et al. Herpes simplex virus encephalitis in human UNC-93B deficiency. Science 2006; 314:308-12. (Pubitemid 44571977)
20. Zhang SY, Jouanguy E, Ugolini S, et al. TLR3 deficiency in patients with herpes simplex encephalitis. Science 2007; 317:1522-7. (Pubitemid 47417427)
21. Perez de Diego R, Sancho-Shimizu V, Lorenzo L, et al. Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis. Immunity 2010; 33:400-11.