The physical structure of the skin barrier

Dermal Absorption and Toxicity Assessment, Second Edition

Volumn , Issue , 2007, Pages 37-68

  Norlén, Lars ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

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EID: 79957739348     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (63)

1. Forslind B. A domain mosaic model of the skin barrier. Acta Derm Venereol (Stockh) 1994; 74:1-6.
2. Norlén L. Skin barrier structure and function: the single gel-phase model. J Invest Dermatol 2001; 117:830-6.
3. Guldbrand L, Jönsson B, Wennerström H. Hydration forces and phase equilibria in the dipalmitoyl phosphatidylcholine-water system. J Colloid Interface Sci 1982; 89:532-41.
4. Evans FD, Wennerström H. The Colloidal Domain: Where Physics, Chemistry, Biology and Technology Meet. New York: VCH Publishers, 1994.
5. Sparr E, Wennerström H. Diffusion through a lamellar liquid crystal: a model of molecular transport across stratum corneum. Colloids Surf B Biointerfaces 2000; 19: 103-16.
6. Peacocke AR. An Introduction to the Physical Chemistry of Biological Organization. New York: Oxford University Press, 1983:1-72.
7. Norlén L. Does the single gel-phase exist in stratum corneum? Reply J Invest Dermatol 2002; 118:899-901.
8. Norlén L, Al-Amoudi A, Dubochet J. A cryo-transmission electron microscopy study of skin barrier formation. J Invest Dermatol 2003; 120:555-60.
9. Masich S, Ostberg T, Norlen L, et al. A procedure to deposit fiducial markers on vitreous cryo-sections for cellular tomography. J Struct Biol 2006; 156:461-8.
10. Al-Amoudi A, Dubochet J, Norlén L. Nanostructure of the epidermal extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin. J Invest Dermatol 2005; 124:764-77.
11. Small DM. The Physical Chemistry of Lipids. Handbook of Lipid Research. New York:Plenum Press, 1986.
12. Israelachvili JN. Intermolecular and Surface Forces. 2nd ed. San Diego: Academic Press, 1992.
13. Larsson K. Lipids: Molecular Organisation, Physical Functions and Technical Applications. Dundee, Scotland: The Oily Press, 1994.
14. Norlén L, Al-Amoudi A. Stratum corneum keratin structure, function, and formation:the cubic rod-packing and membrane templating model. J Invest Dermatol 2004; 123:715-32.
15. Dubochet J, Adrian M, Chang J-J, et al. Cryo-electron microscopy of vitrified specimens. Q Rev Biophys 1988; 21:129-228.
16. Al-Amoudi A, Chang J-J, Leforestier A, et al. Cryo-electron microscopy of vitreous sections. EMBO J 2004; 1523(18):3583-8.
17. Brody I. Ultrastructure of the stratum corneum. Int J Dermatol 1977; 16:245-56.
18. Norlén L. Skin barrier formation: the membrane folding model. J Invest Dermatol 2001; 117:823-9.
19. Landmann L. Epidermal permeability barrier: transformation of lamellar granule-disks into intercellular sheets by a membrane-fusion process, a freeze-fracture study. J Invest Dermatol 1986; 87:202-9.
20. Spicer PT, Hayden KL, Lynch ML, et al. Novel process for producing cubic liquid crystalline nanoparticles (cubosomes). Langmuir 2001; 17:5748-56.
21. Rawlings A. Stratum corneum moisturization at the molecular level: an update in relation to the dry skin cycle. J Invest Dermatol 2005; 124:1099-110.
22. Fartasch M, Bassukas ID, Diepgen T. Structural relationship between epidermal lipid lamellae, lamellar bodies and desmosomes in human epidermis: an ultrastructural study. Br J Dermatol 1993; 128:1-9.
23. Lundström A, Egelrud T. Cell shedding from human plantar skin in vitro: evidence on its dependence on endogenous proteolysis. J Invest Dermatol 1988; 91:340-3.
24. Skerrow CJ, Clelland DG, Skerrow D. Change to desmosomal antigens and lecithinbinding sites during differentiation in normal human epidermis: a quantitative study. J Cell Sci 1989; 92:667-77.
25. Chapman SJ, Walsh A. Desmosomes, corneosomes and desquamation. An ultrastructural study of adult pig epidermis. Arch Dermatol Res 1990; 282:304-10.
26. Mils V, Vincent C, Croute F, et al. The expression of desmosomal and corneodesmosomal antigens shows specific variations during terminal differentiation of epidermis and hair follicle epithelia. J Histochem Cytochem 1992; 40:1329-37.
27. Haftek M, Teillon M-H, Schmitt D. Stratum corneum, corneodesmosomes and ex-vivo percutaneous penetration. Microsc Res Tech 1998; 43:242-9.
28. Pfeiffer S, Vielhaber G, Vietzke J-P, et al. High-pressure freezing provides new information on human epidermis: simultaneous protein antigen and lamellar lipid structure preservation. Study on human epidermis by cryoimmobilization. J Invest Dermatol 2000; 114:1030-8.
29. Landh T. Cubic cell membrane architectures-taking another look at membrane bound cell spaces. Thesis, Department of Food Technology, Lund University, Sweden, 1996.
30. Tandler B, Moribier LG. Ultrastructure of pseudochromosomes and calottes in spermatogenic cells of the backswimmer. Notonecta undulata (Say). Tissue Cell 1974; 6:557-72.
31. Pathak RK, Luskey KL, Anderson RGW. Biogenesis of the crystalloid endoplasmic reticulum in UT-1 cells: evidence that the newly formed endoplasmatic reticulum emerges from the nuclear envelope. J Cell Biol 1986; 102:2158-68.
32. Ahn JNH. Les corps myéloıdes de l’épithelium pigmentaire rétinien. I Répartition, morphologie et rapports avec les organites cellulaires. Z Zellforsch 1971; 115:508-23.
33. Hayward AF. Ultrastructural changes in contents of membrane-coating granules after extrusion from epithelial cells of hamster cheek pouch. Cell Tissue Res 1978; 187:323-31.
34. Swartzendruber DC, Manganaro A, Madison KC, et al. Organization of the intercellular spaces of porcine epidermal and palatal stratum corneum: a quantitative study employing ruthenium tetroxide. Cell Tissue Res 1995; 279:271-6.
35. Elias PM, Cullander C, Mauro T, et al. The secretory granular cell: the outermost granular cell as a specialized secretory cell. J Invest Dermatol Symp Proc 1998; 3(2):87-100.
36. Luzzati V. Biological significance of lipid polymorphism: the cubic phases. Curr Opin Struct Biol 1997; 7:661-8.
37. Menon GK, Feingold KR, Elias P. Lamellar body secretory response to barrier disruption. J Invest Dermatol 1992; 98:279-89.
38. Madison KC, Swartzendruber DC, Wertz PW, et al. Presence of intact intercellular lamellae in the upper layers of the stratum corneum. J Invest Dermatol 1987; 88:714-8.
39. Swartzendruber DC, Wertz PW, Kitko DJ, et al. Molecular models of the intercellular lipid lamellae in mammalian stratum corneum. J Invest Dermatol 1989; 92:251-7.
40. Hou SYE, Mitra AK, White SH, et al. Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and X-ray diffraction. J Invest Dermatol 1991; 96:215-23.
41. Garson J-C, Doucet J, Lévêque J-L, et al. Oriented structure in human stratum corneum revealed by x-ray diffraction. J Invest Dermatol 1991; 96:43-9.
42. Bouwstra JA, Gooris GS, Van der Spek JA, et al. Structural investigations of human stratum corneum by small-angle x-ray scattering. J Invest Dermatol 1991; 97:1005-12.
43. Schreiner V, Gooris GS, Pfeiffer S, et al. Barrier characteristics of different human skin types investigated with X-ray diffraction, lipid analysis, and electron microscopy imaging. J Invest Dermatol 2000; 114:654-60.
44. Ohta N, Ban S, Tanaka H, et al. Swelling of the intercellular lipid lamellar structure with short repeat in hairless mouse stratum corneum as studied by X-ray diffraction. Chem Phys Lipids 2003; 123:1-8.
45. Garrod DR, Merritt AJ, Nie Z. Desmosomal cadherins. Curr Opin Cell Biol 2002; 14:537-45.
46. Schlüter H, Wepf R, Moll I, et al. Sealing the live part of the skin: the integrated meshwork of desmosomes, tight junctions and curvilinear ridge structures in the cells of the uppermost granular layer of the human epidermis. Eur J Cell Biol 2004; 83:655-65.
47. Furuse M, Hata M, Furuse K, et al. Claudin-based tight-junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice. J Cell Biol 2002; 156:1099-111.
48. Norlén L. Molecular skin barrier models and some central problems for the understanding of skin barrier structure and function. Skin Pharm Appl Physiol 2003; 16:203-11.
49. Michaels AS, Chandrasekaran SK, Shaw JE. Drug permeation through human skin:theory and in vitro experimental measurements. AICHE J 1975; 21:985-96.
50. Engström S, Forslind B, Engblom J. Lipid polymorphism-a key to the understanding of skin penetration. In:Brain KR, James VJ, Walters KA, eds. Prediction of Percutaneous Penetration. Vol. 4b. Cardiff: STS Publishing, 1995;163-6.
51. Sparr. Responding model membranes-lipid phase behaviour, domain formation and permeability. Thesis, Department of Physical Chemistry I, Lund University, Sweden 2001.
52. Mesquita R, Melo E, Thompson TE, et al. Partitioning of amphiphiles between coexisting ordered and disordered phases in two-phase lipid bilayer membranes. Biophys J 2000; 78:3019-25.
53. Kitson N, Thewalt J, Lafleur M, et al. A model membrane approach to the epidermal permeability barrier. Biochemistry 1994; 33:6707-15.
54. Ongpipattanakul B, Francoeur ML, Potts RO. Polymorphism in stratum corneum lipids. Biochim Biophys Acta 1994; 1990:115-22.
55. Forslind B, Engström S, Engblom J, et al. A novel approach to the understanding of human skin barrier function. J Dermatol Sci 1997; 14:115-25.
56. Wertz P, Norlén L. “Confidence intervals” for the “true” lipid composition of the human skin barrier. In:Forslind B, Lindberg M, eds. Skin, Hair and Nails-Structure and Function. New York: Marcel Dekker, 2003;85-106.
57. Wertz PW, Swartzendruber DC, Madison KC, et al. Composition and morphology of epidermal cyst lipids. J Invest Dermatol 1987; 89:419-24.
58. Bortz JT, Wertz PW, Downing DT. On the origin of alkanes found in human skin surface lipids. J Invest Dermatol 1989; 93:723-7.
59. Wertz PW, Michniak B B. Sebum. In:Elsner P, Maibach HI, eds. Cosmeceuticals. New York: Marcel Dekker, 2000;45-56.
60. Norlén L, Nicander I, Lundsjö A, et al. A new HPLC-based method for the quantitative analysis of inner stratum corneum lipids with special reference to the free fatty acid fraction. Arch Dermatol Res 1998; 290:508-16.
61. Norlén L, Nicander I, Lundh-Rozell B, et al. Inter and intra individual differences in human stratum corneum lipid content related to physical parameters of skin barrier function in-vivo. J Invest Dermatol 1999; 112:72-7.
62. Vietzke J-P, Brandt O, Abeck D, et al. Comparative investigation of human stratum corneum ceramides. Lipids 2001; 36:299-304.
63. Farwanah H, Wohlrab J, Neubert RHH, et al. Profiling of human stratum corneum ceramides by means of normal phase LC/APCI-MS. Anal Bioanal Chem 2005; 383:632-7.