Myelomonocytic THP-1 cells for in vitro testing of immunomodulatory properties of nanoparticles

Journal of Biomedical Nanotechnology

Volumn 7, Issue 1, 2011, Pages 209-210

  Schroecksnadel, Sebastian ^a   Jenny, Marcel ^a   Fuchs, Dietmar ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

In vitro; In vivo; Inflammation; Nanomaterials

Indexed keywords

CELL LINES; HUMAN PERIPHERAL BLOOD; IN VIVO; IN-VITRO; INFLAMMATION; NEOPTERIN;

AMINO ACIDS; CELL CULTURE;

NANOPARTICLES;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KYNURENINE; LIPOPOLYSACCHARIDE; NANOPARTICLE; NEOPTERIN; TRYPTOPHAN; CYTOKINE; IMMUNOLOGIC FACTOR;

ARTICLE; CELL INTERACTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; MYELOMONOCYTIC LEUKEMIA; PERIPHERAL BLOOD MONONUCLEAR CELL; T LYMPHOCYTE; CELL LINE; DRUG EFFECT; IMMUNOLOGY; INNATE IMMUNITY; MYELOID LEUKEMIA;

CELL LINE; CYTOKINES; HUMANS; IMMUNITY, INNATE; IMMUNOLOGIC FACTORS; IMMUNOMODULATION; LEUKEMIA, MYELOID; LIPOPOLYSACCHARIDES; NANOPARTICLES;

EID: 79957679395     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2011.1272     Document Type: Article

References (3)

1. M. Jenny, M. Klieber, D. Zaknun, S. Schroecksnadel, K. Kurz, M. Ledochowski, H. Schennach, and D. Fuchs, In vitro testing for antiinflammatory properties of compounds employing peripheral blood mononuclear cells freshly isolated from healthy donors. Inflamm. Res. (2010), in press.
2. G. Neurauter, B. Wirleitner, A. Laich, H. Schennach, G. Weiss, and D. Fuchs, Atorvastatin suppresses interferon-γ-induced neopterin formation and tryptophan degradation in human peripheral blood mononuclear cells and in monocytic cell lines. Clin. Exp. Immunol. 131, 264 (2003).
3. S. Schroecksnadel, M. Jenny, K. Kurz, A. Klein, M. Ledochowski, F. Uberall, and D. Fuchs, LPS-induced NF-κB expression in THP-1Blue cells correlates with neopterin production and activity of indoleamine 2,3-dioxygenase. BBRC 399, 642 (2010).