Multidrug-resistant acinetobacter baumannii harboring OXA-24 carbapenemase, Spain

Emerging Infectious Diseases

Volumn 17, Issue 6, 2011, Pages 1064-1067

  Acosta, Joshi ^a   Merino, María ^b   Viedma, Esther ^a   Poza, Margarita ^b   Sanz, Francisca ^a   Otero, Joaquín R ^a   Chaves, Fernando ^a   Bou, Germán ^b  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b UNIVERSITY OF A CORUÑA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CARBAPENEMASE; CEFEPIME; CEFTAZIDIME; GENTAMICIN; IMIPENEM; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TOBRAMYCIN;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; ADULT; AGED; ARTICLE; BACTERIAL STRAIN; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HOSPITAL INFECTION; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; RETROSPECTIVE STUDY; SPAIN;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; ADULT; AGED; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BETA-LACTAMASES; DISEASE OUTBREAKS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; HUMANS; INCIDENCE; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; SPAIN;

EID: 79957634038     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid1706.091866     Document Type: Article

References (15)

1. del Mar Tomas M, Cartelle M, Pertega S, Beceiro A, Llinares P, Canle D, et al. Hospital outbreak caused by a carbapenem-resistant strain of Acinetobacter baumannii: patient prognosis and risk-factors for colonisation and infection. Clin Microbiol Infect. 2005;11:540-546. doi:10.1111/j.1469-0691.2005.01184.x
2. Corbella X, Montero A, Pujol M, Dominguez MA, Ayats J, Argerich MJ, et al. Emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multiresistant Acinetobacter baumannii. J Clin Microbiol. 2000;38:4086-4095.
3. Lee NY, Lee HC, Ko NY, Chang CM, Shih HI, Wu CJ, et al. Clinical and economic impact of multidrug resistance in nosocomial Acinetobacter baumannii bacteremia. Infect Control Hosp Epidemiol. 2007;28:713-719. doi:10.1086/517954
4. Peleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev. 2008;21:538-582. doi:10.1128/CMR.00058-07
5. Villegas MV, Hartstein AI. Acinetobacter outbreaks, 1977-2000. Infect Control Hosp Epidemiol. 2003;24:284-295. doi:10.1086/502205
6. Naas T, Coignard B, Carbonne A, Blanckaert K, Bajolet O, Bernet C, et al. VEB-1 extended-spectrum β-lactamase-producing Acinetobacter baumannii, France. Emerg Infect Dis. 2006;12:1214-1222.
7. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance defi- nition of health care-associated infection and criteria for specifi c types of infections in the acute care setting. Am J Infect Control. 2008;36:309-332. doi:10.1016/j.ajic.2008.03.002
8. Seifert H, Dolzani L, Bressan R, van der Reijden T, van Strijen B, Stefanik D, et al. Standardization and interlaboratory reproducibility assessment of pulsed-fi eld gel electrophoresis-generated fi ngerprints of Acinetobacter baumannii. J Clin Microbiol. 2005;43:4328-4335. doi:10.1128/JCM.43.9.4328-4335.2005
9. Bartual SG, Seifert H, Hippler C, Luzon MA, Wisplinghoff H, Rodriguez-Valera F. Development of a multilocus sequence typing scheme for characterization of clinical isolates of Acinetobacter baumannii. J Clin Microbiol. 2005;43:4382-90. doi:10.1128/JCM.43.9.4382-4390.2005
10. Bou G, Oliver A, Martinez-Beltran J. OXA-24, a novel class D betalactamase with carbapenemase activity in an Acinetobacter baumannii clinical strain. Antimicrob Agents Chemother. 2000;44:1556-1561. doi:10.1128/AAC.44.6.1556-1561.2000
11. Merino M, Acosta J, Poza M, Sanz F, Beceiro A, Chaves F, et al. OXA-24 carbapenemase gene fl anked by XerC/XerD-like recombination sites in different plasmids from different Acinetobacter species isolated during a nosocomial outbreak. Antimicrob Agents Chemother. 2010;54:2724-7. doi:10.1128/AAC.01674-09
12. Rosado CJ, Kondos S, Bull TE, Kuiper MJ, Law RH, Buckle AM, et al. The MACPF/CDC family of pore-forming toxins. Cell Microbiol. 2008;10:1765-1774. doi:10.1111/j.1462-5822.2008.01191.x
13. Dorsey CW, Tolmasky ME, Crosa JH, Actis LA. Genetic organization of an Acinetobacter baumannii chromosomal region harbouring genes related to siderophore biosynthesis and transport. Microbiology. 2003;149:1227-1238. doi:10.1099/mic.0.26204-0
14. Torres AG, Redford P, Welch RA, Payne SM. TonB-dependent systems of uropathogenic Escherichia coli: aerobactin and heme transport and TonB are required for virulence in the mouse. Infect Immun. 2001;69:6179-85. doi:10.1128/IAI.69.10.6179-6185.2001
15. Reeves SA, Torres AG, Payne SM. TonB is required for intracellular growth and virulence of Shigella dysenteriae. Infect Immun. 2000;68:6329-6336. doi:10.1128/IAI.68.11.6329-6336.2000