-
2
-
-
77955930318
-
Effectiveness and safety of Tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
-
Karim QA, Karim SS, Frohlich JA et al.: Effectiveness and safety of Tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 329, 1168-1174 (2010).
-
(2010)
Science
, vol.329
, pp. 1168-1174
-
-
Karim, Q.A.1
Karim, S.S.2
Frohlich, J.A.3
-
3
-
-
78650549662
-
Preexposure chemoprophylaxis for HIV prevention in men who have sex with men
-
Grant RM, Lama JR, Anderson PL et al.: Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N. Engl. J. Med. 363, 2587-2599 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 2587-2599
-
-
Grant, R.M.1
Lama, J.R.2
Anderson, P.L.3
-
4
-
-
0037190597
-
Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: A randomised controlled trial
-
DOI 10.1016/S0140-6736(02)11079-8
-
Van Damme L, Ramjee G, Alary M et al.: Effectiveness of Col-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomized controlled trial. Lancet 360, 971-977 (2002). (Pubitemid 35284107)
-
(2002)
Lancet
, vol.360
, Issue.9338
, pp. 971-977
-
-
Van Damme, L.1
Ramjee, G.2
Alary, M.3
Vuylsteke, B.4
Chandeying, V.5
Rees, H.6
Sirivongrangson, P.7
Mukenge-Tshibaka, L.8
Ettiegne-Traore, V.9
Uaheowitchai, C.10
Abdool Karim, S.S.11
Masse, B.12
Perriens, J.13
Laga, M.14
-
5
-
-
44349126694
-
SAAVY (C31G) vaginal gel for prevention of HIV infection in women: A Phase III, double-blind, randomized, placebocontrolled trial in Ghana
-
Peterson L, Nanda K, Opoku BK et al.: SAAVY (C31G) vaginal gel for prevention of HIV infection in women: a Phase III, double-blind, randomized, placebocontrolled trial in Ghana. PLoS ONE 2, E1312 (2007).
-
(2007)
PLoS ONE
, vol.2
-
-
Peterson, L.1
Nanda, K.2
Opoku, B.K.3
-
6
-
-
57049091723
-
Efficacy of Carraguard for prevention of HIV infection in women in South Africa: A randomised, double-blind, placebo-controlled trial
-
Skoler-Karpoff S, Ramgee G, Ahmed K et al.: Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial. Lancet 372, 1977-1987 (2008).
-
(2008)
Lancet
, vol.372
, pp. 1977-1987
-
-
Skoler-Karpoff, S.1
Ramgee, G.2
Ahmed, K.3
-
7
-
-
48249154985
-
Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission
-
VanDamme L, Govinden R, Mirembe F et al.: Lack of effectiveness of cellulose sulfate gel for the prevention of vaginal HIV transmission. N. Engl. J. Med. 359, 463-472 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 463-472
-
-
Vandamme, L.1
Govinden, R.2
Mirembe, F.3
-
8
-
-
79954804509
-
Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women
-
Abdool Karim SS, Coletti A, Richardson B et al.: Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women. AIDS 25(7), 957-966 (2011).
-
(2011)
AIDS
, vol.25
, Issue.7
, pp. 957-966
-
-
Abdool Karim, S.S.1
Coletti, A.2
Richardson, B.3
-
9
-
-
77954848121
-
At last, vaginal gel scores victory against HIV
-
Cohen J: At last, vaginal gel scores victory against HIV. Science 329, 374-375 (2010).
-
(2010)
Science
, vol.329
, pp. 374-375
-
-
Cohen, J.1
-
11
-
-
78649703085
-
A powerful and perplexing new HIV prevention tool
-
Cohen J: A powerful and perplexing new HIV prevention tool. Science 330, 1298-1299 (2010).
-
(2010)
Science
, vol.330
, pp. 1298-1299
-
-
Cohen, J.1
-
12
-
-
78649435148
-
Preclinical evaluation of anti-HIV microbicide products: New models and biomarkers
-
Doncel GF, Clark MR: Preclinical evaluation of anti-HIV microbicide products: new models and biomarkers. Antiviral Res. 88(Suppl. 1), S10-S18 (2010).
-
(2010)
Antiviral Res.
, vol.88
, Issue.SUPPL. 1
-
-
Doncel, G.F.1
Clark, M.R.2
-
13
-
-
0030997133
-
Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: Retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase
-
Borkow G, Barnard J, Nguyen TM et al.: Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase. J. Virol. 71, 3023-3030 (1997). (Pubitemid 27119946)
-
(1997)
Journal of Virology
, vol.71
, Issue.4
, pp. 3023-3030
-
-
Borkow, G.1
Barnard, J.2
Nguyen, T.M.3
Belmonte, A.4
Wainberg, M.A.5
Parniak, M.A.6
-
14
-
-
34248384307
-
Preclinical safety assessments of UC781 anti-human immunodeficiency virus topical microbicide formulations
-
Patton DN, Cosgrove Sweener YT, Balkus E et al.: Preclinical safety assessments of UC781 anti-human immunodeficiency virus topical microbicide formulations. Antimicrob. Agents Chemother. 51, 1608-1615 (2007).
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 1608-1615
-
-
Patton, D.N.1
Cosgrove Sweener, Y.T.2
Balkus, E.3
-
15
-
-
33745842280
-
Ex vivo culture of human colorectal tissue for the evaluation of candidate microbicides
-
DOI 10.1097/01.aids.0000232230.96134.80, PII 0000203020060612000003
-
Fletcher PS, Elliot J, Grivel J-C et al.: Ex vivo culture of human colorectal tissue for the evaluation of candidate microbicides. AIDS 20, 1237-1245 (2006). (Pubitemid 44030371)
-
(2006)
AIDS
, vol.20
, Issue.9
, pp. 1237-1245
-
-
Fletcher, P.S.1
Elliott, J.2
Grivel, J.-C.3
Margolis, L.4
Anton, P.5
McGowan, I.6
Shattock, R.J.7
-
16
-
-
59749098155
-
Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor
-
Fletcher P, Harmon S, Azijn H et al.: Inhibition of human immunodeficiency virus type 1 infection by the candidate microbicide dapivirine, a nonnucleoside reverse transcriptase inhibitor. Antimicrob. Agents Chemother. 53, 487-495 (2009).
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 487-495
-
-
Fletcher, P.1
Harmon, S.2
Azijn, H.3
-
17
-
-
68649117176
-
Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women
-
Nel AM, Coplan P, van de Wijgert et al.: Safety, tolerability, and systemic absorption of dapivirine vaginal microbicide gel in healthy, HIV-negative women. AIDS 23, 1531-1538 (2009).
-
(2009)
AIDS
, vol.23
, pp. 1531-1538
-
-
Nel, A.M.1
Wijgert De Van, C.P.2
-
18
-
-
5644247983
-
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
-
DOI 10.1126/science.1099288
-
Lederman MM, Veazey RS, Offord R et al.: Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5. Science 306, 485-487 (2004). (Pubitemid 39372448)
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 485-487
-
-
Lederman, M.M.1
Veazey, R.S.2
Offord, R.3
Mosier, D.E.4
Dufour, J.5
Mefford, M.6
Piatak Jr., M.7
Lifson, J.D.8
Salkowitz, J.R.9
Rodriguez, B.10
Blauvelt, A.11
Hartley, O.12
-
19
-
-
56649122050
-
Highly potent, fully recombinant anti-HIV chemokines: Reengineering a low-cost microbicide
-
Gaertner H, Cerini F, Escola J-M et al.: Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide. Proc. Natl Acad. Sci. USA 105, 17706-17711 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 17706-17711
-
-
Gaertner, H.1
Cerini, F.2
Escola, J.-M.3
-
20
-
-
0030790094
-
Discovery of cyanovirin-N, a novel human immunodeficiency virus- inactivating protein that binds viral surface envelope glycoprotein gp120: Potential applications to microbicide development
-
Boyd MR, Gustafson KR, McMahon JB et al.: Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. Antimicrob. Agents Chemother. 41, 1521-1530 (1997). (Pubitemid 27289680)
-
(1997)
Antimicrobial Agents and Chemotherapy
, vol.41
, Issue.7
, pp. 1521-1530
-
-
Boyd, M.R.1
Gustafson, K.R.2
McMahon, J.B.3
Shoemaker, R.H.4
O'Keefe, B.R.5
Mori, T.6
Gulakowski, R.J.7
Wu, L.8
Rivera, M.I.9
Laurencot, C.M.10
Currens, M.J.11
Cardellina II, J.H.12
Buckheit Jr., R.W.13
Nara, P.L.14
Pannell, L.K.15
Sowder II, R.C.16
Henderson, L.E.17
-
21
-
-
0035028207
-
Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner
-
Bolmstedt AJ, O'Keefe BR, Shenoy SR et al.: Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner. Mol. Pharmacol. 59, 949-954 (2001). (Pubitemid 32381571)
-
(2001)
Molecular Pharmacology
, vol.59
, Issue.5
, pp. 949-954
-
-
Bolmstedt, A.J.1
O'Keefe, B.R.2
Shenoy, S.R.3
Mcmahon, J.B.4
Boyd, M.R.5
-
22
-
-
0042368611
-
Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89.6P in macaques
-
DOI 10.1089/088922203322230897
-
Tsai CC, Emau P, Jiang Y et al.: Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89.6P in macaques. AIDS Res. Hum. Retroviruses 19, 535-541 (2003). (Pubitemid 36900571)
-
(2003)
AIDS Research and Human Retroviruses
, vol.19
, Issue.7
, pp. 535-541
-
-
Tsai, C.-C.1
Emau, P.2
Jiang, Y.3
Tian, B.4
Morton, W.R.5
Gustafson, K.R.6
Boyd, M.R.7
-
23
-
-
0742272702
-
Cyanovirin-N nnhibits AIDS virus infections in vaginal transmission models
-
DOI 10.1089/088922204322749459
-
Tsai CC, Emau P, Jiang Y et al.: Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models. AIDS Res. Hum. Retroviruses. 20, 11-18 (2004). (Pubitemid 38147172)
-
(2004)
AIDS Research and Human Retroviruses
, vol.20
, Issue.1
, pp. 11-18
-
-
Tsai, C.-C.1
Emau, P.2
Jiang, Y.3
Agy, M.B.4
Shattock, R.J.5
Schmidt, A.6
Morton, W.R.7
Gustafson, K.R.8
Boyd, M.R.9
-
24
-
-
33749532310
-
Engineered vaginal Lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N
-
DOI 10.1128/AAC.00493-06
-
Liu X, Lagenaur LA, Simpson DA et al.: Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N. Antimicrob. Agents Chemother. 50, 3250-3259 (2006). (Pubitemid 44527495)
-
(2006)
Antimicrobial Agents and Chemotherapy
, vol.50
, Issue.10
, pp. 3250-3259
-
-
Liu, X.1
Lagenaur, L.A.2
Simpson, D.A.3
Essenmacher, K.P.4
Frazier-Parker, C.L.5
Liu, Y.6
Tsai, D.7
Rao, S.S.8
Hamer, D.H.9
Parks, T.P.10
Lee, P.P.11
Xu, Q.12
-
26
-
-
20144370949
-
Isolation and characterization of Griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp
-
DOI 10.1074/jbc.M411122200
-
Mori T, O'Keefe BR, Sowder RC 2nd et al.: Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp. J. Biol. Chem. 280, 9345-9353 (2005). (Pubitemid 40409628)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.10
, pp. 9345-9353
-
-
Mori, T.1
O'Keefe, B.R.2
Sowder II, R.C.3
Bringans, S.4
Gardella, R.5
Berg, S.6
Cochran, P.7
Turpin, J.A.8
Buckheit Jr., R.W.9
McMahon, J.B.10
Boyd, M.R.11
-
27
-
-
34547109661
-
Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide
-
DOI 10.1111/j.1600-0684.2007.00242.x
-
Emau P, Tian B, O'Keefe BR et al.: Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide. J. Med. Primatol. 36, 244-253 (2007). (Pubitemid 47103488)
-
(2007)
Journal of Medical Primatology
, vol.36
, Issue.4-5
, pp. 244-253
-
-
Emau, P.1
Tian, B.2
O'Keefe, B.R.3
Mori, T.4
McMahon, J.B.5
Palmer, K.E.6
Jiang, Y.7
Bekele, G.8
Tsai, C.-C.9
-
28
-
-
65549099593
-
Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component
-
O'Keefe BR, Vojdani F, Buffa V et al.: Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component. Proc. Natl Acad. Sci. USA 106, 6099-6104 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 6099-6104
-
-
O'Keefe, B.R.1
Vojdani, F.2
Buffa, V.3
-
29
-
-
79957592318
-
A Phase 1 randomized controlled trial of a triple anti-HIV-1 monoclonal antibody vaginal microbicide
-
Presented At, Boston, MA, USA, 27 February-2 March
-
Morris G, Wiggins R, Woodhall S et al.: A Phase 1 randomized controlled trial of a triple anti-HIV-1 monoclonal antibody vaginal microbicide. Presented at: 18th Conference on Retroviruses and Opportunistic Infections. Boston, MA, USA, 27 February-2 March 2011.
-
(2011)
18th Conference on Retroviruses and Opportunistic Infections
-
-
Morris, G.1
Wiggins, R.2
Woodhall, S.3
|