Development of lesions and tissue distribution of parasite in lambs orally infected with sporulated oocysts of Toxoplasma gondii

Veterinary Parasitology

Volumn 179, Issue 1-3, 2011, Pages 209-215

  Benavides, J ^a   Maley, S ^a   Pang, Y ^a   Palarea, J ^b   Eaton, S ^a   Katzer, F ^a   Innes, E A ^a   Buxton, D ^a   Chianini, F ^a  

^a MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^b BIOMATHEMATICS AND STATISTICS SCOTLAND   (United Kingdom)

Author keywords

Oocysts; Pathology; Sheep; Tissue cysts; Toxoplasma gondii

Indexed keywords

PROTOZOON ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DISEASE; CONTROLLED STUDY; EXPERIMENTAL MODEL; FEMALE; FEVER; FOREBRAIN; GLIA; HISTOPATHOLOGY; HOST PARASITE INTERACTION; IMMUNOHISTOCHEMISTRY; INTERSTITIAL PNEUMONIA; LAMB; LIVER DISEASE; LYMPHOID HYPERPLASIA; MESENCEPHALON; MOUTH INFECTION; MYOSITIS; NONHUMAN; OOCYST; RECTUM TEMPERATURE; SEROLOGY; SHEEP DISEASE; SPOROGENESIS; TACHYZOITE; TISSUE DISTRIBUTION; TOXOPLASMA GONDII;

ANIMALS; CENTRAL NERVOUS SYSTEM DISEASES; HOST-PARASITE INTERACTIONS; SHEEP; SHEEP DISEASES; SPORES, PROTOZOAN; TIME FACTORS; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL;

ANIMALIA; OVIS ARIES; TOXOPLASMA GONDII;

EID: 79957593103     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2011.03.001     Document Type: Article

References (24)

1. Barragan A., Sibley L.D. Migration of Toxoplasma gondii across biological barriers. Trends Microbiol. 2003, 11(9):426-430.
2. Blader I.J., Saeij J.P. Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence. APMIS 2009, 117(5-6):458-476.
3. Buxton D., Blewett D.A., Trees A.J., McColgan C., Finlayson J. Further studies in the use of monensin in the control of experimental ovine toxoplasmosis. J. Comp. Pathol. 1988, 98(2):225-236.
4. Buxton D., Miller H.R., Finlayson J., Wallace G.R. Toxoplasma gondii: its effect on the ovine popliteal lymph node. J. Med. Microbiol. 1981, 14(4):435-442.
5. Buxton D., Maley S.W., Thomson K.M., Trees A.J., Innes E.A. Experimental infection of non-pregnant and pregnant sheep with Neospora caninum. J. Comp. Pathol. 1997, 117(1):1-16.
6. Buxton D., Thomson K.M., Maley S., Wastling J.M., Innes E.A., Panton W.R., Nicoll S. Primary and secondary responses of the ovine lymph node to Toxoplasma gondii: cell output in efferent lymph and parasite detection. J. Comp. Pathol. 1994, 111(3):231-241.
7. Dellacasa-Lindberg I., Hitziger N., Barragan A. Localized recrudescence of Toxoplasma infections in the central nervous system of immunocompromised mice assessed by in vivo bioluminescence imaging. Microbes Infect. 2007, 9(11):1291-1298.
8. Dorny P., Praet N., Deckers N., Gabriel S. Emerging food-borne parasites. Vet. Parasitol. 2009, 163(3):196-206.
9. Dubey J.P. Comparative infectivity of Toxoplasma gondii bradyzoites in rats and mice. J. Parasitol. 1998, 84(6):1279-1282.
10. Dubey J.P. The history of Toxoplasma gondii-the first 100 years. J. Eukaryot. Microbiol. 2008, 55(6):467-475.
11. Dubey J.P. Toxoplasmosis in sheep-the last 20 years. Vet. Parasitol. 2009, 163(1-2):1-14.
12. Dubey J.P., Frenkel J.K. Toxoplasmosis of rats: a review, with considerations of their value as an animal model and their possible role in epidemiology. Vet. Parasitol. 1998, 77(1):1-32.
13. Dubey J.P., Speer C.A., Shen S.K., Kwok O.C., Blixt J.A. Oocyst-induced murine toxoplasmosis: life cycle, pathogenicity, and stage conversion in mice fed Toxoplasma gondii oocysts. J. Parasitol. 1997, 83(5):870-882.
14. Esteban-Redondo I., Innes E.A. Detection of Toxoplasma gondii in tissues of sheep orally challenged with different doses of oocysts. Int. J. Parasitol. 1998, 28(9):1459-1466.
15. Esteban-Redondo I., Maley S.W., Thomson K., Nicoll S., Wright S., Buxton D., Innes E.A. Detection of T. gondii in tissues of sheep and cattle following oral infection. Vet. Parasitol. 1999, 86(3):155-171.
16. Falcón J., Freyre A. Toxoplasma gondii: prototype immunization of lambs against formation of muscle and brain cysts. Vet. Parasitol. 2009, 166(1-2):15-20.
17. Ferguson D.J., Graham D.I., Hutchison W.M. Pathological changes in the brains of mice infected with Toxoplasma gondii: a histological, immunocytochemical and ultrastructural study. Int. J. Exp. Pathol. 1991, 72(4):463-474.
18. Innes E.A. Toxoplasmosis: comparative species susceptibility and host immune response. Comp. Immunol. Microbiol. Infect. Dis. 1997, 20(2):131-138.
19. Innes E.A., Wastling J.M. Analysis of in vivo immune responses during Toxoplasma gondii infection using the technique of lymphatic cannulation. Parasitol. Today 1995, 11(7):268-271.
20. Innes E.A., Panton W.R., Sanderson A., Thomson K.M., Wastling J.M., Maley S., Buxton D. Induction of CD4+ and CD8+ T cell responses in efferent lymph responding to Toxoplasma gondii infection: analysis of phenotype and function. Parasite Immunol. 1995, 17(3):151-160.
21. Jongert E., Roberts C.W., Gargano N., Förster-Wald E., Petersen E. Vaccines against Toxoplasma gondii: challenges and opportunities. Mem. Inst. Oswaldo Cruz. 2009, 104(2):252-266.
22. McColgan C., Buxton D., Miller H.R. Studies on ovine efferent lymph following infection with Toxoplasma gondii. J. Comp. Pathol. 1987, 97(6):695-703.
23. McColgan C., Buxton D., Blewett D.A. Titration of Toxoplasma gondii oocysts in non-pregnant sheep and the effects of subsequent challenge during pregnancy. Vet. Rec. 1988, 123(18):467-470.
24. Skariah S., McIntyre M.K., Mordue D.G. Toxoplasma gondii: determinants of tachyzoite to bradyzoite conversion. Parasitol. Res. 2010, 107(2):253-260.