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Volumn 52, Issue 26, 2011, Pages 3376-3378

Rapid synthesis of diversely functionalized 3,4,7-trisubstituted indoles

Author keywords

[No Author keywords available]

Indexed keywords

4 ALKOXY 3 CYANOINDOLE 7 CARBOXAMIDE; 4 ALKOXYINDOLE 7 CARBOXAMIDE; AMIDE; INDOLE DERIVATIVE; ISOCYANIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

EID: 79957590551     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.04.086     Document Type: Article
Times cited : (6)

References (30)
  • 4
    • 33744738548 scopus 로고    scopus 로고
    • For an example of carbonylation of a similar indole see: A.B. Smith III, L. Kürti, and A.H. Davulcu Org. Lett. 8 2006 2167 2170
    • (2006) Org. Lett. , vol.8 , pp. 2167-2170
    • Kürti, L.1    Davulcu, A.H.2
  • 13
    • 79957614901 scopus 로고    scopus 로고
    • The yield of 10 is based on the NMR purity of a crude weight
    • The yield of 10 is based on the NMR purity of a crude weight.
  • 14
  • 17
    • 0141741411 scopus 로고    scopus 로고
    • We found only one example in which a carboxamide was directly introduced at C-7 of an indole, accomplished by directed ortho metallation. See: C.G. Hartung, A. Fecher, B. Chapell, and V. Snieckus Org. Lett. 5 2003 1899 1902
    • (2003) Org. Lett. , vol.5 , pp. 1899-1902
    • Hartung, C.G.1    Fecher, A.2    Chapell, B.3    Snieckus, V.4
  • 18
    • 79957598691 scopus 로고
    • German Patent DE 1010958, June 27
    • Graf, R. Carboxylic amides. German Patent DE 1010958, June 27, 1957.
    • (1957) Carboxylic Amides
    • Graf, R.1
  • 20
    • 79957591370 scopus 로고    scopus 로고
    • In some of our previous cyanations with CSI we had noticed two minor byproducts, one corresponding to the indole-3-carboxamide, and another which appeared to result from a second addition of CSI to the indole
    • In some of our previous cyanations with CSI we had noticed two minor byproducts, one corresponding to the indole-3-carboxamide, and another which appeared to result from a second addition of CSI to the indole.
  • 21
    • 79957591140 scopus 로고    scopus 로고
    • The identity of 15 was confirmed by NMR
    • The identity of 15 was confirmed by NMR.
  • 30
    • 79957595736 scopus 로고    scopus 로고
    • note
    • 2O: C, 59.17; H, 3.58; N, 20.70. Found: C, 58.97; H, 3.37; N, 20.50.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.