Cytotoxicity and Oral acute toxicity studies of lantana camara leaf extract

Molecules

Volumn 16, Issue 5, 2011, Pages 3663-3674

  Pour, Mahdi Badakhshan ^a   Latha, Lachimanan Yoga ^b   Sasidharan, Sreenivasan ^b  

^a AIMST UNIVERSITY   (Malaysia)

^b SCHOOL OF PHYSICS   (Malaysia)

Author keywords

Cytotoxicity; Lantana camara; Oral acute toxicity; Plant extract; Vero cell

Indexed keywords

PLANT EXTRACT;

ANIMAL; ARTICLE; CELL PROLIFERATION; CERCOPITHECUS; CHEMISTRY; DRUG EFFECT; FEMALE; HEART; KIDNEY; LANTANA; MALE; METHODOLOGY; MOUSE; PLANT LEAF; TOXICITY TESTING; VERO CELL;

ACUTE TOXICITY TESTS; ANIMALS; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; FEMALE; HEART; KIDNEY; LANTANA; MALE; MICE; PLANT EXTRACTS; PLANT LEAVES; VERO CELLS;

EID: 79957586815     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules16053663     Document Type: Article

References (30)

1. Badakhshan, M.P.; Sasidharan, S.; Rameshwar, N.J.; Ramanathan, S. Comparative study: Antimicrobial activity of methanol extracts of Lantana camara Various Parts. Phcog. Res. 2009, 1 (6), 348-351.
2. Abou-Karam, M.; Shier, W.T. A simplified plaque reduction assay for antiviral agents from plants. Demonstration of frequent occurrence of antiviral activity in higher plants. J. Nat. Prod. 1990, 53 (2), 340-344. (Pubitemid 20202672)
3. Afolayan, A.J.; Meyer, J.J.M. The antimicrobial activity of 3,5,7-trihydroxyflavone isolated from the shoots of Helichrysum aureonitens. J. Ethnopharmacol. 1997, 57 (3), 177-181. (Pubitemid 27389099)
4. Hernández, T.; Canales, M.; Avila, J.G.; Duran, A.; Caballero, J.R.; Vivar, A.; Lira, R. Ethnobotany and antibacterial activity of some plants used in traditional medicine of Zapotitlán de las Salinas, Puebla (México). J. Ethnopharmacol. 2003, 88 (2-3), 181-188. (Pubitemid 37083444)
5. Muthu, C.; Ayyanar, M.; Raja, N.; Ignacimuthu, S. Medicinal plants used by traditional healers in Kancheepuram District of Tamil Nadu, India. J. Ethnobiol. Ethnomed. 2006, 2 (1), 43.
6. McKenzie, R.A. Bentonite as therapy for Lantana camara poisoning of cattle. Vet. J. 1991, 68 (4), 146-148.
7. Ghisalberti, E.L. Lantana camara L. (Verbenaceae). Fitoterapia 2000, 71 (5), 467-486 (Pubitemid 30646015)
8. Mahdi-Pour, B.; Sasidharan, S. In vivo toxicity study of Lantana camara. Asian Pac. J. Trop. Biomed. 2011, 1(3), 230-232.
9. O'Neill, M.J.; Lewis, J.A.; Noble, H.M.; Holland, S.; Mansat, C.; Farthing, J.E.; Foster, G.; Noble, D.; Lane, S.J.; Sidebottom, P.J.; et al. Isolation of translactone-containing triterpenes with thrombin inhibitory activities from the leaves of Lantana camara. J. Nat. Prod. 1998, 61 (11), 1328-1331. (Pubitemid 28555091)
10. Uzcategui, B.; Avila, D.; Heberto, S.R.; Quintero, L.; Ortega, J.; Gonzalez, Y.B. Anti-inflammatory, antinociceptive and antipyretic effects of Lantana trifolia Linnaeus in experimental animals. Invest. Clin. 2004, 45 (4), 317-322. (Pubitemid 39647940)
11. Sagar, L.; Sehgal, R.; Ojha, S. Evaluation of antimotility effect of Lantana camara L. var. acuelata constituents on neostigmine induced gastrointestinal transit in mice. BMC Complement Altern Med. 2005, 5, 18.
12. Johnson, J.H.; Jensen, J.M. Hepatotoxicity and secondary photosensitization in a red kangaroo (Megaleia rufus) due to ingestion of Lantana camara. J. Zoo Wildl. Med. 1998, 29 (2), 203-207. (Pubitemid 128657112)
13. Sharma, O.P.; Dawra, R.K.; Makkar, H.P. Effect of polymorphic crystal forms of lantana toxins on icterogenic action in guinea pigs. Toxicol. Lett. 1988, 42 (1), 29-37.
14. Garg, S.K.; Shah, M.A.; Garg, K.M.; Farooqui, M.M.; Sabir, M. Antilymphocytic and immunosuppressive effects of L. camara leaves in rats. Indian J. Exp. Biol. 1997, 35 (12), 1315-1318. (Pubitemid 28011602)
15. Black, H.; Carter, R.G. Lantana poisoning of cattle and sheep in New Zealand. N. Z. Vet. J. 1985, 33 (8), 136-137.
16. Sharma, O.P.; Dawra, R.K.; Makkhar, H.P. Toxicity of isolated lantana (L. camara L.) constituents to male and female guinea pigs. Vet. Hum. Toxicol. 1989, 31 (1), 10-13. (Pubitemid 19039373)
17. Jackson, M.R. The nature of dimethylnitrosamine induced enlargement of rat hepatocyte nuclei. J. Pathol. 1974, 113 (3), 197-208.
18. Saini, N.; Singh, J.; Sehgal, R.; Ojha, S. Evaluation of liver function impairment and lipid peroxidation induced by Lantana camara leaf powder administration in adult rat serum and liver. Cell Mol. Biol. (Noisy-le-grand) 2007, 53 (5), 79-83. (Pubitemid 350164308)
19. Sharma, O.P.; Dawra, R.K.; Makkar, H.P. Isolation and partial purification of Lantana (Lantana camara L.) toxins. Toxicol. Lett. 1987, 37 (2), 165-172. (Pubitemid 17097335)
20. Sharma, O.P.; Vaid, J.; Pattabhi, V.; Bhutani, K.K. Biological action of lantadene C, a new hepatotoxicant from Lantana camara var. aculeata. J. Biochem. Toxicol. 1992, 7 (2), 73-79.
21. Hart, N.K.; Lamberton, J.A.; Sioumis, A.A.; Suares, H.; Seawright, A.A. Triterpenes of toxic and non-toxic taxa of Lantana camara. Experientia. 1976, 32 (4), 412-413.
22. 2 in water hyacinth leaf. Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao. 2006, 32 (2), 189-194.
23. Misra, L.; Laatsch, H. Triterpenoids, essential oil and photo-oxidative 28 → 13-lactonization of oleanolic acid from Lantana camara. Phytochemistry 2000, 54 (8), 969-974.
24. Srivastava, P.; Sisodia, V.; Chaturvedi, R. Effect of culture conditions on synthesis of triterpenoids in suspension cultures of Lantana camara L. Bioprocess Biosyst. Eng. 2011, 34 (1), 75-80
25. Srivastava, P.; Kasoju, N.; Bora, U.; Chaturvedi, R. Dedifferentiation of leaf explants and cytotoxic activity of an aqueous extract of cell cultures of Lantana camara L. Plant Cell Tissue Organ Cult. 2009, 99 (1), 1-7.
26. Srivastava, P.; Kasoju, N.; Bora, U.; Chaturvedi, R. Accumulation of Betulinic, Oleanolic, and Ursolic acids in in vitro cell cultures of Lantana camara L. and their significant cytotoxic effects on HeLa cell lines. Biotechnol. Bioprocess Eng. 2010, 15 (6), 1038-1046.
27. Srivastava, P.; Chaturvedi, R. Simultaneous determination and quantification of three pentacyclic triterpenoids-betulinic acid, oleanolic acid, and ursolic acid-in cell cultures of Lantana camara L. 2010 In Vitro Cell Dev. Biol. - Plant 2010, 46 (6), 549-557.
28. OECD Guidelines for Testing of Chemicals. No 420: Acute Oral Toxicity-fixed Dose Method, Organisation for Economic Co-operation and Development: Paris, France, 1992.
29. Lee, J.N.; Park, C.S.; Kim, H.P.; Hwang, S.Y.; Chung, W.G. Single dose toxicity study of Hwangjaegongjinbo, an invigorator, in mice and rats. J. Toxicol. Pub. Health 2002, 18 (1), 73-77.
30. Ryu, S.D.; Park, C.S.; Baek, H.M.; Baek, S.H.; Hwang, S.Y.; Chung, W.G. Antidiarrheal and spasmolytic activities and acute toxicity study of Soonkijangquebo, a herbal anti-diarrheal formula. J. Ethnopharmacol. 2004, 91 (1), 75-80.