Lack of efficacy of topical calcineurin inhibitor pimecrolimus 1% on pruritus of severely uremic patients: A randomized double-blind study in 60 patients

Dermatitis

Volumn 22, Issue 3, 2011, Pages 167-168

  Ghorbani, Ali Reza ^a   Feily, Amir ^b   Khalili, Ali ^a   Dormanesh, Benafshe ^c  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c AJA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

PIMECROLIMUS; PLACEBO; TACROLIMUS;

ADULT; BURNING SENSATION; CHRONIC KIDNEY FAILURE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; HEMODIALYSIS PATIENT; HUMAN; LETTER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PRURITUS; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; SHORT COURSE THERAPY; TREATMENT DURATION; UREMIC PRURITUS; VISUAL ANALOG SCALE;

ADMINISTRATION, TOPICAL; ADULT; CALCINEURIN; DOUBLE-BLIND METHOD; HUMANS; IMMUNOSUPPRESSIVE AGENTS; PRURITUS; SEVERITY OF ILLNESS INDEX; TACROLIMUS; TREATMENT OUTCOME; UREMIA;

EID: 79957583552     PISSN: 17103568     EISSN: None     Source Type: Journal    
DOI: 10.2310/6620.2011.10110     Document Type: Letter

References (5)

1. Mettang M, Weisshaar E. Pruritus: control of itch in patients undergoing dialysis. Skin Therapy Lett 2010;15:1-5.
2. Razeghi E, Eskandari D, Ganji M, et al. Gabapentin and uremic pruritus in hemodialysis patients. Ren Failure 2009;31:85-90, doi:10.1080/ 08860220802595476.
3. Kuypers DR, Claes K, Evenepoel P, et al. A prospective proof of concept study of the efficacy of tacrolimus ointment on uremic pruritus in patients on chronic dialysis therapy. Nephrol Dial Transplant 2004;19:1895-901, doi:10.1093/ndt/gfh202. (Pubitemid 38961406)
4. Pauli-Magnus C, Klumpp S, Alscher DM, et al. Short-term efficacy of tacrolimus ointment in severe uremic pruritus. Perit Dial Int 2000;20:802-3.
5. Duque MI, Yosipovitch G, Fleischer AB Jr, et al. Lack of efficacy of tacrolimus ointment 0.1% for treatment of hemodialysis-related pruritus: a randomized, double-blind, vehicle-controlled study. J Am Acad Dermatol 2005;52:519-21, doi:10.1016/j.jaad.2004.08.050.