PASS assisted prediction and pharmacological evaluation of novel nicotinic analogs for nootropic activity in mice

European Journal of Pharmacology

Volumn 662, Issue 1-3, 2011, Pages 22-30

  Khurana, Navneet ^a,b   Ishar, Mohan Pal Singh ^a   Gajbhiye, Asmita ^b   Goel, Rajesh Kumar ^c  

^a GURU NANAK DEV UNIVERSITY   (India)

^b DR H S GOUR UNIVERSITY   (India)

^c PUNJABI UNIVERSITY   (India)

Author keywords

Acetylcholine esterase activity; Nicotine acetylcholine receptor; Nicotine analog; Nootropic agent

Indexed keywords

2,5 DIPHENYL 3 (3 PYRIDYL) ISOXAZOLIDINE; 5 ISOBUTOXY 2 PHENYL 3 (3 PYRIDYL ISOXAZOLIDINE); CHOLINESTERASE INHIBITOR; DONEPEZIL; NICOTINE; NICOTINE DERIVATIVE; NOOTROPIC AGENT; PYRIDINE DERIVATIVE; SCOPOLAMINE; UNCLASSIFIED DRUG;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLINERGIC SYSTEM; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TOLERABILITY; FEMALE; LOCOMOTION; LOW DRUG DOSE; MOTOR COORDINATION; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SINGLE DRUG DOSE; STRUCTURE ANALYSIS; TOBACCO DEPENDENCE;

ACETYLCHOLINESTERASE; ANIMALS; COGNITION; COMPUTATIONAL BIOLOGY; DRUG EVALUATION, PRECLINICAL; FEMALE; LOCOMOTION; MEMORY; MICE; MUSCLES; NICOTINE; NOOTROPIC AGENTS; REACTION TIME; RECEPTORS, NICOTINIC; SCOPOLAMINE;

EID: 79957581414     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.04.048     Document Type: Article

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