High-dose split-course radiation therapy for anal cancer: Outcome analysis regarding the boost strategy (CORS-03 Study)

International Journal of Radiation Oncology Biology Physics

Volumn 80, Issue 3, 2011, Pages 712-720

  Hannoun Levi, Jean Michel ^a,h   Ortholan, Cécile ^a   Resbeut, Michel ^b,h   Teissier, Eric ^c,h   Ronchin, Philippe ^c   Cowen, Didier ^d,h   Zaccariotto, Audrey ^d   Bénézery, Karen ^a   Franois, Eric ^a   Salem, Naji ^e,h   Ellis, Steve ^f,h   Azria, David ^g,h   Gerard, Jean Pierre ^a  

^a CENTRE ANTOINE LACASSAGNE   (France)

^b French Red Cross   (France)

^c Azurean Cancer Center   (France)

^d Timone Teaching Hospital   (France)

^e INSTITUT PAOLI CALMETTES   (France)

^f Catalan Oncology Center   (France)

^g CENTRE VAL D AURELLE   (France)

^h Cercle des Oncologues Radiothérapeutes du Sud C O R S   (France)

Author keywords

Anal cancer; Boost technique; Brachytherapy; Intersequence gap; Radiation therapy; Split course

Indexed keywords

ANAL CANCER; BOOST TECHNIQUE; BRACHYTHERAPY; INTERSEQUENCE GAP; RADIATION THERAPY; SPLIT-COURSE;

DISEASES; MULTIVARIANT ANALYSIS; ONCOLOGY; PATIENT MONITORING; TUMORS;

RADIOTHERAPY;

CISPLATIN; FLUOROURACIL;

ADJUVANT CHEMOTHERAPY; ADULT; AGED; ANUS CANCER; ARTICLE; BRACHYTHERAPY; CANCER INVASION; CANCER PATIENT; CANCER RECURRENCE; CANCER STAGING; COLOSTOMY; CONTROLLED STUDY; EXTERNAL BEAM RADIOTHERAPY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; RECTUM ABDOMINOPERINEAL RESECTION; SQUAMOUS CELL CARCINOMA; TREATMENT DURATION;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANUS NEOPLASMS; BRACHYTHERAPY; CARCINOMA, SQUAMOUS CELL; CARCINOMA, TRANSITIONAL CELL; FEMALE; FOLLOW-UP STUDIES; FRANCE; HUMANS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; RADIOTHERAPY; RADIOTHERAPY DOSAGE; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 79957544196     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.02.055     Document Type: Article

References (34)

1. P.R. Fleshner, S. Chalasani, and G.J. Chang Standards Practice Task Force, American Society of Colon and Rectal Surgeons. Practice parameters for anal squamous neoplasms Dis Colon Rectum 51 2008 2 9
2. A. Jemal, R. Siegel, and E. Ward Cancer statistics, 2007 CA Cancer J Clin 57 2007 43 66 (Pubitemid 46148091)
3. P.M. Recio Radical surgery in the treatment of epidermoid carcinoma of the anal canal Philipp J Surg 10 1955 1 8
4. E.G. Harrison Jr., O.H. Beahrs, and J.R. Hill Anal and perianal malignant neoplasms: pathology and treatment Dis Colon Rectum 9 1966 255 267
5. J. Papillon, M. Dargent, and A. Pinet Irradiation with curative aim in cancer of the rectum and anus J Radiol Electrol Med Nucl 42 1961 818 820
6. J. Papillon, J.F. Montbarbon, and J.L. Chassard Radiotherapy of malpighian cancers of the anus: Role of interstitial curietherapy, alone or combined with cobalt therapy, in the treatment of epidermoid cancers of the anus J Radiol Electrol Med Nucl 54 1973 627 633
7. N.D. Nigro, V.K. Vaitkevicius, and B. Considine Jr. Combined therapy for cancer of the anal canal: A preliminary report Dis Colon Rectum 17 1974 354 356
8. B.J. Cummings, T.J. Keane, and B. OSullivan Epidermoid anal cancer: Treatment by radiation alone or by radiation and 5-fluorouracil with and without mitomycin C Int J Rad Oncol Biol Phys 21 1991 1115 1125
9. Epidermoid anal cancer: Results from the UKCCCR randomized trial of radiotherapy alone versus radiotherapy, 5-fluorouracil, and mitomycin Lancet 348 1996 1049 1054
10. M. Flam, M. John, and T.F. Pajak Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: Results of a phase 3 randomized intergroup study J Clin Oncol 14 1996 2527 2539 (Pubitemid 26300120)
11. H. Bartelink, F. Roelofsen, and F. Eschwege Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of Phase 3 randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups J Clin Oncol 15 1997 2040 2049 (Pubitemid 27209535)
12. J.P. Gerard, L. Ayzac, and D. Hun Treatment of anal canal carcinoma with high dose radiation therapy and concomitant fluorouracil-cisplatinum: Long-term results in 95 patients Radiother Oncol 46 1998 249 256 (Pubitemid 28157274)
13. J. Papillon, M. Mayer, and J.F. Montbarbon A new approach to the management of epidermoid carcinoma of the anal canal Cancer 51 1983 1830 1837 (Pubitemid 13093951)
14. J. Papillon, J.F. Montbarbon, and J.P. Gerard Interstitial curietherapy in the conservative treatment of anal and rectal cancers Int J Radiat Oncol Biol Phys 17 1989 1161 1169 (Pubitemid 20028631)
15. International Classification of Diseases. Rev. ed. Geneva: World Health Organization. 1965. p. 196.
16. Anal canal American Joint Committee on Cancer. AJCC cancer staging manual 6th ed. 2002 Springer New York p. 125-130
17. Dose and volume specification for reporting interstitial therapy. International Commission on Radiation Units Measurements. ICRU 58, Dose and volume specification for reporting interstitial therapy. 1998.
18. A. Dutreix, and G. Marinello The Paris system B. Pierquin, J.F. Wilson, D. Chassagne, Modern brachytherapy 1987 Masson New York 27 42
19. M. Schemper, and T.L. Smith A note on quantifying follow-up in studies of failure time Control Clin Trials 17 1996 343 346 (Pubitemid 26342716)
20. E.C. Constantinou, W. Daly, and C.Y. Fung Time-dose considerations in the treatment of anal cancer Int J Radiat Oncol Biol Phys 39 1997 651 657 (Pubitemid 27441432)
21. D.C. Weber, J.M. Kurtz, and A.S. Allal The impact of gap duration on local control in anal canal carcinoma treated by split-course radiotherapy and concomitant chemotherapy Int J Radiat Oncol Biol Phys 50 2001 675 680 (Pubitemid 32519596)
22. R. Graf, P. Wust, and B. Hildebrandt Impact of overall treatment time on local control of anal cancer treated with radiochemotherapy Oncology 65 2003 14 22 (Pubitemid 36829086)
23. L.S. Pang, and B.C. Morson Basaloid carconoma of the anal canal J Clin Pathol 20 1967 128 135
24. T.A. Longacre, C.S. Kong, and M.L. Welton Diagnostic problems in anal pathology Adv Anat Pathol 15 2008 263 278
25. E. Deniaud-Alexandre, E. Touboul, and E. Tiret Results of definitive irradiation in a series of 305 epidermoid carcinomas of the anal canal Int J Radiat Oncol Biol Phys 56 2003 1259 1273 (Pubitemid 36842877)
26. M. Ferre, A. Courdi, and J.M. Hannoun-Levi Dose gradient impact on biological equivalent dose for accelerated partial breast irradiation using high dose rate interstitial brachytherapy (Abstract) Int J Radiat Oncol Biol Phys 70 Suppl. 1 2008 2799
27. A. Niemierko Reporting and analyzing dose distributions: A concept of equivalent uniform dose Med Phys 24 1997 103 110 (Pubitemid 27051935)
28. R. Ferrigno, R.A. Nakamura, and P.E. Dos Santos Novaes Radiochemotherapy in the conservative treatment of anal canal carcinoma: Retrospective analysis of results and radiation dose effectiveness Int J Radiat Oncol Biol Phys 61 2005 1136 1142 (Pubitemid 40340908)
29. K. Huang, D. Haas-Kogan, and V. Weinberg Higher radiation dose with a shorter treatment duration improves outcome for locally advanced carcinoma of anal canal World J Gastroenterol 13 2007 895 900 (Pubitemid 46470300)
30. J. Widder, R. Kastenberger, and E. Fercher Radiation dose associated with local control in advanced anal cancer: Retrospective analysis of 129 patients Radiother Oncol 87 2008 367 375
31. R. Glynne-Jones, J. Northover, and J. Oliveira ESMO Guidelines Working Group. Anal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up Ann Oncol 20 Suppl. 4 2009 57 60
32. R. James, H. Meadows, and S. WanACT II The second UK phase III anal cancer trial Clin Oncol 17 2005 364 366 (Pubitemid 40932110)
33. R. James, S. Wan, and R. Glynne-Jones A randomized trial of chemoradiation using mitomycin or cisplatin, with or without maintenance cisplatin/5FU in squamous cell carcinoma of the anus (ACT II) (Abstract) J Clin Oncol 27 2009 18s
34. FFCD ACCORD-3 clinical trial: Combination chemotherapy plus radiation therapy in treating patients with Stage II or Stage III anal cancer. http://clinicaltrials.gov/ct2/show/NCT00003652. Accessed 10/11/2009.