Dynamics of plasma proteome during leptin-replacement therapy in genetically based leptin deficiency

Pharmacogenomics Journal

Volumn 11, Issue 3, 2011, Pages 174-190

  Andreev, V P ^a   Dwivedi, R C ^b   Paz Filho, G ^c   Krokhin, O V ^b   Wong, M L ^c   Wilkins, J A ^b   Licinio, J ^c  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

^c Biology and Environment   (Australia)

Author keywords

enrichment analysis; insulin resistance; iTRAQ; leptin; obesity; plasma proteome

Indexed keywords

ADENYLYL CYCLASE ASSOCIATED PROTEIN 1; ADIPONECTIN PRECURSOR; ALPHA ACTININ 1; ALPHA ENOLASE; ALPHA TROPOMYOSIN; ANDROGEN RECEPTOR; CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1; COFILIN; FILAMIN A; KINDLIN 3; LACTATE DEHYDROGENASE; MEMBRANE PROTEIN; MOESIN; MYC PROTEIN; PLATELET BASIC PROTEIN PRECURSOR; PLECKSTRIN; PROFILIN I; PROTEIN 14 3 3; PROTEOME; RECOMBINANT LEPTIN; RHO GDP DISSOCIATION INHIBITOR 1; STRATIFIN; TALIN 1; THROMBOSPONDIN 1 PRECURSOR; UNCLASSIFIED DRUG; VINCULIN; ZYXIN;

ADULT; ARTICLE; BLOOD CLOTTING; CASE REPORT; CYTOSKELETON; DRUG DOSE TITRATION; EVENING DOSAGE; FEMALE; GLUCONEOGENESIS; GLYCOLYSIS; HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; INSULIN RESISTANCE; LEPTIN DEFICIENCY; LIPOPROTEIN METABOLISM; MALE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN METABOLISM; PROTEOMICS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ADULT; BLOOD PROTEINS; CELL ADHESION; CYTOSKELETON; FEMALE; GENE THERAPY; GLUCONEOGENESIS; GLYCOLYSIS; HORMONE REPLACEMENT THERAPY; HUMANS; INSULIN RESISTANCE; LEPTIN; MALE; METABOLIC NETWORKS AND PATHWAYS; PROTEOME;

EID: 79957509734     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/tpj.2010.30     Document Type: Article

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