Symptom-adjusted therapy in asthma: It is time to listen to our patients

Expert Review of Clinical Immunology

Volumn 7, Issue 3, 2011, Pages 259-261

  Bhat, K Deepa ^a   Calhoun, William J ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

as needed inhaled corticosteroid use; asthma therapy; inhaled corticosteroid use; rescue treatment; symptom based treatment

Indexed keywords

BIOLOGICAL MARKER; CORTICOSTEROID; SHORT ACTING DRUG; ZAFIRLUKAST;

ABSENCE OF SIDE EFFECTS; ASTHMA; CLINICAL PRACTICE; DOUBLE BLIND PROCEDURE; EDITORIAL; GENETIC POLYMORPHISM; HUMAN; LUNG FUNCTION; MORTALITY; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PHYSICIAN; PRACTICE GUIDELINE; RANDOMIZED CONTROLLED TRIAL (TOPIC); SYMPTOM; TREATMENT FAILURE;

ANTI-ASTHMATIC AGENTS; ASTHMA; COMBINED MODALITY THERAPY; HUMANS; TREATMENT OUTCOME;

EID: 79957440249     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/eci.11.17     Document Type: Editorial

References (14)

1. NHLBI National Asthma Expert Panel 2007 Guidelines for the Diagnosis and Management of Asthma. NIH, MD, USA (NIH Publication 08-4051) (2007).
2. Rabe KF, Adachi M, Lai CK et al. Worldwide severity and control of asthma in children and adults: the global asthma insights and reality surveys. J. Allergy Clin. Immunol. 114, 40-47 (2004). (Pubitemid 39022491)
3. Cho SH. Pharmacogenomic approaches to asthma treatment. Allergy Asthma Immunol. Res. 2(3), 177-182 (2010).
4. Szefler SJ, Mitchell HM, Sorkness CA et al. Adding Exhaled Nitric Oxide to Guideline-based Asthma Treatment in Inner-City Adolescents and Young Adults: a randomized controlled trial. Lancet 372, 1065-1072 (2008).
5. Smith AD, Cowan JO, Brassett KP et al. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N. Engl. J. Med. 352, 2163-2173 (2005).
6. Boushey HA, Sorkness CA, King TS et al. Daily versus as-needed corticosteroids for mild persistent asthma. N. Engl. J. Med. 352, 1519-1528 (2005).
7. Papi A, Canonica GW, Maestrelli P et al. Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma. N. Engl. J. Med. 356, 2040-2052 (2007). (Pubitemid 46789894)
8. O'Byrne PM, Bisgaard H, Godard P et al. Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma. Am. J. Respir. Crit. Care Med. 171, 129-136 (2005). (Pubitemid 40105411)
9. Rabe KF, Pizzochini E, Stallberg B et al. Budesonide/Formoterol in a Single Inhaler for Maintenance and Relief in Mild-to-Moderate Asthma: a randomized, double blind trial. Chest 129, 246-256 (2006). (Pubitemid 43289841)
10. Bisgaard H, Le Roux P, Bjamer D et al. Budesonide/formoterol maintenance plus reliever therapy: a new strategy in pediatric asthma. Chest 130, 1733-1743 (2006). (Pubitemid 46033427)
11. Oborne J, Mortimer K, Hubbard RB, Tattersfield AE, Harrison TW. Quadrupling the dose of inhaled corticosteroid to prevent asthma exacerbations: a randomized, double-blind, placebo-controlled parallel-group clinical trial. Am. J. Respir. Crit. Care Med. 180(7), 598-602 (2009).
12. Foresi A, Morelli MC, Catena E. Low-dose budesonide with the addition of an increased dose during exacerbations is effective in long-term asthma control. Chest 117(2), 440-446 (2000). (Pubitemid 30111596)
13. Martinez F, Chinchilli V, Morgan W et al. Use of Beclomethasone Diproprionate as Rescue Treatment for Children with Mild Persistent Asthma (TREXA): a randomized, double-blind, placebo-controlled trial. Lancet 377, 650-657 (2011).
14. Calhoun WJ, Ameredes BT, King TS et al. Comparison of Inhaled Corticosteroid Adjustment Strategies for Long Term Asthma Management: The ACRN BASALT Trial. Presented at: The American Academy of Allergy, Asthma & Immunology. San Francisco, CA, USA, 18-22 March 2011 (Oral abstract).