Prenatal exposure to ethanol: A specific effect on the H19 gene in sperm

Reproductive Toxicology

Volumn 31, Issue 4, 2011, Pages 507-512

  Stouder, Christelle ^a   Somm, Emmanuel ^a   Paoloni Giacobino, Ariane ^a,b  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Epigenetics; Ethanol; Fertility; Methylation; Sperm

Indexed keywords

ALCOHOL; CELL DNA; GENE PRODUCT; PROTEIN GTL2; PROTEIN PEG1; PROTEIN PEG3; RNA H19; SMALL NUCLEAR RIBONUCLEOPROTEIN; SOMATOMEDIN B; TRANSCRIPTION FACTOR CTCF; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN TISSUE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; FEMALE; GENE EXPRESSION REGULATION; GENE TARGETING; GENOME IMPRINTING; MALE; MOUSE; NEWBORN; NONHUMAN; PREGNANCY OUTCOME; PRENATAL EXPOSURE; PROGENY; PROTEIN BINDING; SOMATIC CELL GENETICS; SPERMATOGENESIS; SPERMATOZOON DENSITY; TERATOGENICITY;

ALCOHOL DRINKING; ANIMALS; BRAIN; CPG ISLANDS; DNA METHYLATION; ETHANOL; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOMIC IMPRINTING; GESTATIONAL AGE; MALE; MATERNAL EXPOSURE; MICE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RNA, UNTRANSLATED; SPERM COUNT; SPERMATOGENESIS; SPERMATOZOA;

MUS;

EID: 79956357684     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2011.02.009     Document Type: Article

References (31)

1. Jones K.L., Smith D.W. Recognition of the fetal alcohol syndrome in early infancy. Lancet 1973, 302:999-1001.
2. Astley S.J. Fetal alcohol syndrome prevention in Washington State: evidence of success. Paediatr Perinat Epidemiol 2004, 18:344-351.
3. Gladstone J., Nulman I., Koren G. Reproductive risks of binge drinking during pregnancy. Reprod Toxicol 1996, 10:3-13.
4. Main K.M., Skakkebaek N.E., Toppari J. Cryptorchidism as part of the testicular dysgenesis syndrome: the environmental connection. Endocr Dev 2009, 14:167-173.
5. Becker H.C., Diaz-Granados J.L., Randall C.L. Teratogenic actions of ethanol in the mouse: a minireview. Pharmacol Biochem Behav 1996, 55:501-513.
6. Endres M., Toso L., Roberson R., Park J., Abebe D., Poggi S., et al. Prevention of alcohol-induced developmental delays and learning abnormalities in a model of fetal alcohol syndrome. Am J Obstet Gynecol 2005, 193:1028-1034.
7. Krahl S.E., Berman R.F., Hannigan J.H. Electrophysiology of hippocampal CA1 neurons after prenatal ethanol exposure. Alcohol 1999, 17:125-131.
8. Nixon K., Crews F.T. Binge ethanol exposure decreases neurogenesis in adult rat hippocampus. J Neurochem 2002, 83:1087-1093.
9. Berman R.F., Hannigan J.H. Effects of prenatal alcohol exposure on the hippocampus: spatial behavior, electrophysiology, and neuroanatomy. Hippocampus 2000, 10:94-110.
10. Shukla S.D., Velazquez J., French S.W., Lu S.C., Ticku M.K., Zakhari S. Emerging role of epigenetics in the actions of alcohol. Alcohol Clin Exp Res 2008, 32:1525-1534.
11. Haycock P.C. Fetal alcohol spectrum disorders: the epigenetic perspective. Biol Reprod 2009, 81:607-617.
12. Garro A.J., McBeth D.L., Lima V., Lieber C.S. Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome. Alcohol Clin Exp Res 1991, 15:395-398.
13. Kaminen-Ahola N., Ahola A., Maga M., Mallitt K.A., Fahey P., Cox T.C., et al. Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model. PLoS Genet 2010, 6:e1000811.
14. Liu Y., Balaraman Y., Wang G., Nephew K.P., Zhou F.C. Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation. Epigenetics 2009, 4:500-511.
15. Muthusami K.R., Chinnaswamy P. Effect of chronic alcoholism on male fertility hormones and semen quality. Fertil Steril 2005, 84:919-924.
16. Ouko L.A., Shantikumar K., Knezovich J., Haycock P., Schnugh D.J., Ramsay M. Effect of alcohol consumption on CpG methylation in the differentially methylated regions of H19 and IG-DMR in male gametes: implications for fetal alcohol spectrum disorders. Alcohol Clin Exp Res 2009, 33:1615-1627.
17. Haycock P.C., Ramsay M. Exposure of mouse embryos to ethanol during preimplantation development: effect on DNA methylation in the h19 imprinting control region. Biol Reprod 2009, 81:618-627.
18. Tremblay K.D., Duran K.L., Bartolomei M.S. A 5' 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development. Mol Cell Biol 1997, 17:4322-4329.
19. Li J.Y., Lees-Murdock D.J., Xu G.L., Walsh C.P. Timing of establishment of paternal methylation imprints in the mouse. Genomics 2004, 84:952-960.
20. Shemer R., Birger Y., Riggs A.D., Razin A. Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern. Proc Natl Acad Sci USA 1997, 94:10267-10272.
21. Kaneko-Ishino T., Kuroiwa Y., Miyoshi N., Kohda T., Suzuki R., Yokoyama M., et al. Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization. Nat Genet 1995, 11:52-59.
22. Kuroiwa Y., Kaneko-Ishino T., Kagitani F., Kohda T., Li L.L., Tada M., et al. Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein. Nat Genet 1996, 12:186-190.
23. Smilinich N.J., Day C.D., Fitzpatrick G.V., Caldwell G.M., Lossie A.C., Cooper P.R., et al. A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome. Proc Natl Acad Sci USA 1999, 96:8064-8069.
24. Reinhart B., Paoloni-Giacobino A., Chaillet J.R. Specific differentially methylated domain sequences direct the maintenance of methylation at imprinted genes. Mol Cell Biol 2006, 26:8347-8356.
25. Chaillet J.R., Bader D.S., Leder P. Regulation of genomic imprinting by gametic and embryonic processes. Genes Dev 1995, 9:1177-1187.
26. Stouder C., Deutsch S., Paoloni-Giacobino A. Superovulation in mice alters the methylation pattern of imprinted genes in the sperm of the offspring. Reprod Toxicol 2009, 28:536-541.
27. Datta S., Turner D., Singh R., Ruest L.B., Pierce W.M.J., Knudsen T.B. Fetal alcohol syndrome (FAS) in C57BL/6 mice detected through proteomics screening of the amniotic fluid. Birth Defects Res A Clin Mol Teratol 2008, 82:177-186.
28. Amini S.A., Dunkley P.R., Murdoch R.N. Teratogenic effects of ethanol in the Quackenbush special mouse. Drug Alcohol Depend 1996, 41:61-69.
29. Fish E.W., Riday T.T., McGuigan M.M., Faccidomo S., Hodge C.W., Malanga C.J. Alcohol, cocaine, and brain stimulation-reward in C57Bl6/J and DBA2/J mice. Alcohol Clin Exp Res 2010, 34:81-89.
30. Kurukuti S., Tiwari V.K., Tavoosidana G., Pugacheva E., Murrell A., Zhao Z., et al. CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci USA 2006, 103:10684-10689.
31. Tycko B., Morison I.M. Physiological functions of imprinted genes. J Cell Physiol 2002, 192:245-258.