The impact of isoniazid preventive therapy and antiretroviral therapy on tuberculosis in children infected with HIV in a high tuberculosis incidence setting

Thorax

Volumn 66, Issue 6, 2011, Pages 496-501

  Frigati, L J ^a   Kranzer, K ^b   Cotton, M F ^c   Schaaf, H S ^c   Lombard, C J ^d   Zar, H J ^a  

^a RED CROSS WAR MEMORIAL CHILDREN S HOSPITAL   (South Africa)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c STELLENBOSCH UNIVERSITY   (South Africa)

^d SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

COTRIMOXAZOLE; EFAVIRENZ; ISONIAZID; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; NEVIRAPINE; PLACEBO; RITONAVIR; STAVUDINE; ZIDOVUDINE;

ANTIVIRAL THERAPY; ARTICLE; CHILD; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; INCIDENCE; INFECTION PREVENTION; INFECTION RISK; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; NUTRITIONAL STATUS; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK REDUCTION;

EID: 79956343795     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thx.2010.156752     Document Type: Article

References (23)

1. Donald PR. Childhood tuberculosis: out of control? Curr Opin Pulm Med 2002;8:178-82.
2. Nelson LJ, Wells CD. Global epidemiology of childhood tuberculosis. Int J Tuberc Lung Dis 2004;8:636-47. (Pubitemid 38625076)
3. Hesseling AC, Cotton MF, Jennings T, et al. High incidence of tuberculosis among HIV-infected infants: evidence from a South African population-based study highlights the need for improved tuberculosis control strategies. Clin Infect Dis 2009;48:108-14.
4. Madhi SA, Petersen K, Madhi A, et al. Increased disease burden and antibiotic resistance of bacteria causing severe community-acquired lower respiratory tract infections in human immunodeficiency virus type 1-infected children. Clin Infect Dis 2000;31:170-6. (Pubitemid 32268959)
5. Jeena PM, Pillay P, Pillay T, et al. Impact of HIV-1 co-infection on presentation and hospital-related mortality in children with culture proven pulmonary tuberculosis in Durban, South Africa. Int J Tuberc Lung Dis 2002;6:672-8. (Pubitemid 34832146)
6. Zar HJ, Hanslo D, Tannenbaum E, et al. Aetiology and outcome of pneumonia in human immunodeficiency virus-infected children hospitalized in South Africa. Acta Paediatr 2001;90:119-25. (Pubitemid 32222792)
7. Anon. Revised BCG vaccination guidelines for infants at risk for HIV infection (in English and French). Wkly Epidemiol Rec Global Advisory Committee on Vaccine Safety 2007;82(21):193-6.
8. Zar HJ, Cotton MF, Strauss S, et al. Effect of isoniazid prophylaxis on mortality and incidence of tuberculosis in children with HIV: randomised controlled trial. BMJ 2007;334:136-43.
9. Walters E, Cotton MF, Rabie H, et al. Clinical presentation and outcome of tuberculosis in human immunodeficiency virus infected children on anti-retroviral therapy. BMC Pediatr 2008;8:1-12.
10. Edmonds A, Lusiama J, Napravnik S, et al. Anti-retroviral therapy reduces incident tuberculosis in HIV-infected children. Int J Epidemiol 2009;38:1612-21.
11. Gray DM, Zar H, Cotton M. Impact of tuberculosis preventive therapy on tuberculosis and mortality in HIV-infected children. Cochrane Database Syst Rev 2009;(1):CD006418.
12. Madhi SA, Nachman S, Violari A, et al. Lack of efficacy of primary isoniazid (INH) prophylaxis in increasing tuberculosis (TB) free survival in HIV-infected (HIV+) South African children. 48th Interscience Conference on Antimicrobial Agents and Chemotherapy, 25-28 October 2008. Washington. Abstract G2-1346a.
13. Anon. Guidance for National Tuberculosis and HIV Programmes on the Management of Tuberculosis in HIV-Infected Children: Recommendations for a Public Health Approach. Geneva, Switerland: World Health Organization, 2010.
14. Golub JE, Saraceni V, Cavalcante SC, et al. The impact of antiretroviral therapy and isoniazid preventive therapy on tuberculosis incidence in HIV-infected patients in Rio de Janeiro, Brazil. AIDS 2007;21:1441-8. (Pubitemid 46988004)
15. Golub JE, Pronyk P, Mohapi L, et al. Isoniazid preventive therapy, HAART and tuberculosis risk in HIV-infected adults in South Africa: a prospective cohort. AIDS 2009;23:631-6.
16. Marais BJ, Hesseling AC, Gie RP. The burden of childhood tuberculosis and the accuracy of routine surveillance data in a high-burden setting. Int J Tuberc Lung Dis 2006;10:259-63.
17. Anon. Antiretroviral Therapy of HIV Infections in Infants and Children: Towards Universal Access. Recommendations for a Public Health Approach. Geneva, Switzerland: World Health Organization, 2006.
18. Gray D, Nuttall J, Lombard C, et al. Low rates of hepatotoxicity in HIV-infected children on anti-retroviral therapy with and without isoniazid prophylaxis. J Trop Pediatr 2010;56:159-65.
19. le Roux SM, Cotton MF, Golub JE, et al. Adherence to isoniazid prophylaxis among HIV-infected children: a randomized controlled trial comparing two dosing schedules. BMC Med 2009;7:67.
20. Hung CC, Chen MY, Hsiao CF, et al. Improved outcomes of HIV-1-infected adults with tuberculosis in the era of highly active antiretroviral therapy. AIDS 2003;17:2615-22.
21. Kampmann B, Tena-Coki GN, Nicol MP, et al. Reconstitution of antimycobacterial immune responses in HIV-infected children receiving HAART. AIDS 2006;20:1011-18.
22. Akolo C, Adetifa I, Shepperd S, et al. Treatment of latent tuberculosis infection in HIV infected persons. Cochrane Database Syst Rev 2010;(1):CD000171.
23. Anon. Global Tuberculosis Control: Epidemiology, Strategy, Financing: WHO Report 2009. Geneva: World Health Organization, 2009.