Transcranial direct current stimulation: Estimation of the electric field and of the current density in an anatomical human head model

IEEE Transactions on Biomedical Engineering

Volumn 58, Issue 6, 2011, Pages 1773-1780

  Parazzini, Marta ^a   Fiocchi, Serena ^a,b   Rossi, Elena ^c   Paglialonga, Alessia ^a   Ravazzani, Paolo ^a  

^a CNR   (Italy)

^b POLITECNICO DI MILANO   (Italy)

^c Newronika Srl   (Italy)

Author keywords

Anatomical human head model; numerical dosimetry; transcranial direct current stimulation

Indexed keywords

AMPLITUDE DISTRIBUTIONS; ANODE AREA; BRAIN STRUCTURE; BRAIN TISSUE; CATHODE AREA; CLINICAL PRACTICES; DIRECT CURRENT; ELECTRODE AREAS; FIELD AMPLITUDES; FIELD DISTRIBUTION; HUMAN HEAD MODEL; INDUCED FIELD; INJECTED CURRENT; MIDBRAIN; NUMERICAL DOSIMETRY; PRIMARY MOTOR CORTEX; TRANSCRANIAL; WHITE MATTER;

CATHODES; DOSIMETRY; ELECTRIC FIELDS; HISTOLOGY; NUMERICAL METHODS; TISSUE;

BRAIN;

ARTICLE; BRAIN CORTEX; BRAIN REGION; BRAIN TISSUE; ELECTRIC FIELD; ELECTRODE; HEAD; TRANSCRANIAL DIRECT CURRENT STIMULATION; WHITE MATTER;

ADULT; BRAIN; COMPUTER SIMULATION; ELECTRIC STIMULATION; ELECTRODES; ELECTROMAGNETIC FIELDS; FEMALE; HEAD; HUMANS; MODELS, ANATOMIC;

EID: 79956340713     PISSN: 00189294     EISSN: 15582531     Source Type: Journal    
DOI: 10.1109/TBME.2011.2116019     Document Type: Article

References (22)

1. M. A. Nitsche and W. Paulus, "Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation," J. Physiol., vol. 527, no. 3, pp. 633-639, Sep. 2000.
2. F. Fregni and A. Pascual-Leone, "Technology insight: noninvasive brain stimulationinneurology-perspectiveson the therapeutic potential of rTMS and tDCS," Nat. Clin. Pract. Neurol., vol. 3, no. 7, pp. 383-393, Jul. 2007. (Pubitemid 47040328)
3. M. A. Nitsche, L. G. Cohen, E. M. Wassermann, A. Priori, N. Lang, A. Antal, W. Paulus, F. Hummel, P. S. Boggio, F. Fregni, and A. Pascual-Leone, "Transcranial direct current stimulation: State of the art 2008," Brain Stimulation, vol. 1, no. 3, pp. 206-223, Jul. 2008.
4. A. Priori, "Brain polarization in humans: A reappraisal of an old tool for prolonged non-invasive modulation of brain excitability," Clin. Neuro-physiol., vol. 114, no. 4, pp. 589-595, Apr. 2003. (Pubitemid 36398580)
5. O. D. Creutzfeldt, G. H. Fromm, and H. Kapp, "Influence of transcortical D-C currents on cortical neuronal activity," Exp. Neurol., vol. 5, pp. 436-452, Jun. 1962.
6. D. P. Purpura and J. G. McMurtry, "Intracellular activities and evoked potential changes during polarization of motor cortex," J. Neurophysiol., vol. 28, pp. 166-185, Jan. 1965.
7. R. N. Holdefer, R. Sadleir, and M. J Russell, "Predicted current densities in the brain during transcranial electrical stimulation," Clin. Neurophysiol., vol. 117, no. 6, pp. 1388-1397, Jun. 2006. (Pubitemid 43841856)
8. P. C. Miranda, M. Lomarev, and M. Hallett, "Modeling the current distribution during transcranial direct current stimulation," Clin. Neurophysiol, vol. 117, no. 7, pp. 1623-1629, Jul. 2006. (Pubitemid 43947714)
9. P. C. Miranda, P. Faria, and M. Hallett, "What does the ratio of injected current to electrode area tell us about current density in the brain during tDCS?," Clin. Neurophysiol, vol. 120, no. 6, pp. 1183-1187, Jun. 2009.
10. A. Datta, M. Elwassif, F. Battaglia, and M. Bikson, "Transcranial current stimulation focality using disc and ring electrode configurations: FEM analysis," J. Neural Eng., vol. 5, no. 2, pp. 163-174, Jun. 2008. (Pubitemid 351999184)
11. A. Datta, V. Bansal, J. Diaz, J. Patel, D. Reato, and M. Bikson, "Gyri-precise head model of transcranial direct current stimulation: Improved spatial focality using a ring electrode versus conventional rectangular pad," Brain Stimulation, vol. 2, no. 4, pp. 201-207, Oct. 2009.
12. T. Wagner, F. Fregni, S. Fecteau, A. Grodzinsky, M. Zahn, and A. Pascual-Leone, "Transcranial direct current stimulation: A computer-based human model study," Neuroimage, vol. 35, no. 3, pp. 1113-1124, Apr. 2007. (Pubitemid 46507817)
13. R. J. Sadleir, T. D. Vannorsdall, D. J. Schretlen, and B. Gordon, "Tran-scranial direct current stimulation (tDCS) in a realistic head model," Neu-roimage, vol. 51, no. 4, pp. 1310-1318, Jul. 2010.
14. F. Fregni, P. S. Boggio, M. Nitsche, F. Bermpohl, A. Antal, E. Feredoes, M. A. Marcolin, S. P. Rigonatti, M. T. Silva, W. Paulus, and A. Pascual-Leone, "Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory," Exp. Brain Res., vol. 166, no. 1, pp. 23-30, Sep. 2005. (Pubitemid 41451033)
15. M. B Iyer, U. Mattu, J. Grafman, M. Lomarev, S. Sato, and E. M. Wasser-mann, "Safety and cognitive effect of frontal dc brain polarization in healthy individuals," Neurology, vol. 64, no. 5, pp. 872-875, Mar. 2005. (Pubitemid 40326256)
16. Christ, W. Kainz, G. E. Hahn, K. Honegger, M. Zefferer, E. Neufeld, W. Rascher, R. Janka, W. Bautz, J. Chen, B. Kiefer, P. Schmitt, H.-P. Hollenbach, J. Shen, M. Oberle, D. Szczerba, A. Kam, J. W. Guag, and N. Kuster, "The Virtual Family\Development of surface-based anatomical models of two adults and two children for dosimetric simulations," Phys. Med. Biol., vol. 55, no. 2, pp. N23-N38, Jan. 2010.
17. S. Gabriel, R. W. Lau, and C. Gabriel, "The dielectric properties of biological tissues\Part II: Measurements in the frequency range 10 Hz to 20 GHz," Phys. Med. Biol., vol. 41, no. 11, pp. 2251-2269, Nov. 1996. (Pubitemid 26376902)
18. IFAC-CNR. (2010, Oct. 21), "An Internet resource for the calculation of the dielectric properties of body tissues," National Research Council, Institute for Applied Physics "Nello Carrara," Florence, Italy [Online]. Available: http://niremf.ifac.cnr.it/tissprop/
19. C. Gabriel, "Comments on 'Dielectric properties of the skin'," Phys. Med. Biol., vol. 42, no. 8, pp. 1671-1674, Aug. 1997.
20. M. A. Nitsche, S. Doemkes, T. Karakose, A. Antal, D. Liebetanz, N. Lang, F. Tergau, and W.Paulus, "Shaping the effectsof transcranial direct current stimulation of the human motor cortex," J. Neurophysiol., vol. 97, no. 4, pp. 3109-3117, Apr. 2007. (Pubitemid 46557737)
21. D. Liebetanz, R. Koch, S. Mayenfels, F. König, W. Paulus, and M. A. Nitsche, "Safety limits of cathodal transcranial direct current stimulation in rats," Clin. Neurophysiol., vol. 120, no. 6, pp. 1161-1167, Jun. 2009.
22. E. J. Tehovnik, "Electrical stimulation of neural tissue to evoke behavioral responses," J. Neurosci. Methods, vol. 65, pp. 1-17, 1996 (Pubitemid 26106371)