Exhaled nitric oxide as a tool in managing and monitoring difficult-to-treat asthma

Allergy and Asthma Proceedings

Volumn 32, Issue 3, 2011, Pages 185-192

  Bukstein, Don ^a   Luskin, Allan T ^a   Brooks, Elizabeth A ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Reimbursement Principles Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; NITRIC OXIDE;

ARTICLE; ASTHMA; COST CONTROL; DISEASE CLASSIFICATION; DISEASE EXACERBATION; DISEASE SEVERITY; EMERGENCY WARD; EXERCISE; FORCED EXPIRATORY VOLUME; HEALTH CARE COST; HEALTH CARE UTILIZATION; HOSPITALIZATION; HUMAN; LUNG FUNCTION TEST; PEAK EXPIRATORY FLOW;

ASTHMA; BREATH TESTS; COST OF ILLNESS; DISEASE PROGRESSION; DRUG RESISTANCE; EMERGENCY SERVICE, HOSPITAL; EXHALATION; GUIDELINES AS TOPIC; HOSPITALIZATION; HUMANS; NITRIC OXIDE; UNITED STATES;

EID: 79956307893     PISSN: 10885412     EISSN: 15396304     Source Type: Journal    
DOI: 10.2500/aap.2011.32.3449     Document Type: Article

References (42)

1. Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention 2009 (update). Available online at www.ginaasthma.org; last accessed September 8, 2010.
2. Griswold SK, Nordstrom CR, Clark S, et al. Asthma exacerbations in North American adults. Chest, 127:5, 2005.
3. Irwin RS, Pratter MR, Holland PS, et al. Postnasal drip causes cough and is associated with reversible upper airway obstruction. Chest 85:346-352, 1984.
4. Global Initiative for Asthma (GINA), National Heart, Lung, and Blood Institute (NHLBI). Global strategy for asthma management and prevention. Updated 2009. GINA NHLBI: Bethesda, MD; Available online at www.ginasthma.com; last accessed December 12, 2010.
5. National Heart, Lung, and Blood Institute. Expert Panel Report 3: Guidelines for the diagnosis and management of asthma. Publication No. 08-4051, 2007. Available online at www.nhlbi.nih.gov/guidelines/asthma/asthgdln.pdf; last accessed December 12, 2010.
6. American Thoracic Society, European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 171:912-930, 2005.
7. (British Thoracic Society. Thorax 58:1-94, 2003.)
8. Hakonarson H, and Halapi E. Genetic analyses in asthma: Current concepts and future directions. Am J Pharmacogenomics 2:155-166, 2002. (Pubitemid 35167862)
9. Taylor DR. Nitric oxide as a clinical guide for asthma management. J Allergy Clin Immunol 117:259-262, 2006. (Pubitemid 43190136)
10. Asthma in America: A landmark survey. National Survey Data, 1998. Available online at www.asthmainamerica.com/cities/national.html; last accessed September 14, 2010.
11. Children and Asthma in America. National Survey Data 2004. Available online at www.asthmainamerica.com/children-index.html; last accessed September 12, 2010.
12. Bateman ED, Boushey HA, Bousquet J, et al. Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study. Am J Respir Crit Care Med 170:836-844, 2004. (Pubitemid 39346477)
13. Crimi E, Spanevello A, Neri M, et al. Dissociation between airway inflammation and airway hyper responsiveness in allergic asthma. Am J Respir Crit Care Med 157:4-9, 1998. (Pubitemid 28071253)
14. Frieri M. Nitric oxide in allergic rhinitis and asthma. Allergy Asthma Proc 19:349-351, 1998. (Pubitemid 128684497)
15. Smith AD, Cowan JO, Filsell S, et al. Diagnosing asthma: Comparisons between exhaled nitric oxide measurements and conventional tests. Am J Respir Crit Care Med 169:473-478, 2004. (Pubitemid 38187119)
16. Sont JK, Willems LNA, Bel EH, et al. Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. Am J Respir Crit Care Med 159:1043-1051, 1999. (Pubitemid 29202534)
17. Green RH, Brightling CE, McKenna S, et al. Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial. Lancet 360:1715-1721, 2002. (Pubitemid 35447900)
18. Patil SU, and Long AA. The usefulness of biomarkers of airway inflammation in managing asthma. Allergy Asthma Proc 31:259-268, 2010.
19. Nicolini G, Chetta A, Simonazzi A, et al. Both bronchial and alveolar exhaled nitric oxide are reduced with extrafine beclomethasone dipropionate in asthma. Allergy Asthma Proc 31:85-90, 2010.
20. Sivan Y, Gadish T, Fireman E, et al. The use of exhaled nitric oxide in the diagnosis of asthma in school children. J Pediatr 155:211-216, 2009.
21. Pijnenburg MW, Bakker EM, Hop WC, et al. Titrating steroids on exhaled nitric oxide in children with asthma: A randomized controlled trial. Am J Respir Crit Care Med 172:831-836, 2005. (Pubitemid 41369065)
22. Schatz M, Mosen D, Apter AJ, et al. Relationships among quality of life, severity, and control measures in asthma: An evaluation using factor analysis. J Allergy Clin Immunol 115:1049-1055, 2005. (Pubitemid 40616222)
23. Leung TF, Wong G, Ko F, et al. Clinical and atopic parameters and airway inflammatory markers in childhood asthma: A factor analysis. Thorax 60:822-826, 2005. (Pubitemid 41475208)
24. Loo RM, Katarzyna K, Kumar K, and Frieri M. Emergency department evaluation, treatment, hospital admission and sIgE levels in African American and Hispanic pediatric asthmatics. Clin Immunol 123(suppl 8):S76, 2007.
25. Huang YC, Leyko BT, and Frieri M. Effects of omalizumab and budesonide on markers of inflammation in human bronchial epithelial cells Ann Allergy Asthma Immunol 95:443-451, 2005.
26. Ohkura N, Fujimura M, Tokuda A, et al. Evaluation of airway hyperresponsiveness and exhaled nitric oxide as risk factors for airway remodeling in patients with stable asthma. Allergy Asthma Proc 30:419-423, 2009.
27. Zitt M. Clinical applications of exhaled nitric oxide for the diagnosis and management of asthma: A consensus report. Clin Ther 27:1238-1250, 2005. (Pubitemid 41393917)
28. Silkoff PE, Carlson M, Bourke T, et al. The Aerocrine exhaled nitric oxide monitoring system Niox is cleared by the US food and drug administration for monitoring therapy in asthma. J Allergy Clin Immunol 114:1241-1256, 2004. (Pubitemid 39469172)
29. Strunk RC, Szefler SJ, Phillips BR, et al. Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children. J Allergy Clin Immunol 112:883-892, 2003. (Pubitemid 37412055)
30. Szefler SJ, Mitchell H, Sorkness CA, et al. Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: A randomised controlled trial. Lancet 372:1065-1072, 2008.
31. Barnes PJ, Dweik RA, Gelb AF, et al. Exhaled nitric oxide in pulmonary diseases: A comprehensive review. Chest 138:3, 2010.
32. Majid H, and Kao C. Utility of exhaled nitric oxide in the diagnosis and management of asthma. Curr Opin Pulm Med 16:42-47, 2010.
33. Kercsmar C. Exhaled nitric oxide in the diagnosis and management of childhood asthma. Ther Adv Resp Dis 4:71-82, 2010.
34. Consensus statement on the use of fractional exhaled nitric oxide (FENO) in the clinical management of asthma (White Paper). National Jewish Health, Denver, CO, December 2009.
35. Barnett SBL, and Nurmagambetov TA. Costs of asthma in the United States: 2002-2007. J Allergy Clin Immunol 127:145-152, 2011.
36. Smith AD, Cowan JO, Brassett KP, et al. Exhaled nitric oxide: A predictor of steroid response. Am J Respir Crit Care Med 172:453-459, 2005. (Pubitemid 41117391)
37. Delgado-Corcoran C, Kissoon N, Murphy SP, et al. Exhaled nitric oxide reflects asthma severity and asthma control. Pediatr Crit Care Med 5:48-52, 2004.
38. Dweik RA, Sorkness RL, Wenzel A, et al. Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma. Am J Respir Crit Care Med. [Epub ahead of print]. 2010 Feb 4.
39. Jones SL, Kittelson J, Cowan JO, et al. The predictive value of exhaled nitric oxide measurements in assesing changes in asthma control. Am J Respir Crit Care Med 164:738-743, 2001. (Pubitemid 32881906)
40. Smith AD, Cowan JO, Brassett KP, et al. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med 352:2163-2173, 2005.
41. Shaw DE, Berry MA, Thomas M, et al. The use of exhaled nitric oxide to guide asthma management: A randomized controlled trial. Am J Respir Crit Care Med 176:231-237, 2007. (Pubitemid 47195872)
42. Ivanova JI, Bergman RE, Birnbaum HG, et al. Cost comparison among moderate or severe persistent asthma patients with and without asthma exacerbations. Am J Respir Crit Care Med 181:A3126, 2010.