Pharmacokinetics and safety of FV-100, a novel oral anti-herpes zoster nucleoside analogue, administered in single and multiple doses to healthy young adult and elderly adult volunteers

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 6, 2011, Pages 2847-2854

  Pentikis, Helen S ^a   Matson, Mark ^b   Atiee, George ^c   Boehlecke, Brian ^d   Hutchins, Jeff T ^e   Patti, Joseph M ^e   Henson, Geoffrey W ^e   Morris, Amy ^e,f  

^a SAJE Consulting LLC   (United States)

^b PRISM Research Inc   (United States)

^c ICON Development Solutions   (United States)

^d RHO INC   (United States)

^e Inhibitex Inc   (United States)

^f IND 2 Results LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; CF 1743; FV 100; PLACEBO; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIVIRAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG EXPOSURE; DRUG SAFETY; DRUG TOLERABILITY; DRUG URINE LEVEL; FEMALE; GROUPS BY AGE; HERPES ZOSTER; HUMAN; HUMAN EXPERIMENT; LIPID DIET; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; POSTHERPETIC NEURALGIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; URINARY EXCRETION;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGE FACTORS; AGED; ANTIVIRAL AGENTS; DOUBLE-BLIND METHOD; FEMALE; HERPES ZOSTER; HUMANS; MALE; MIDDLE AGED; PRODRUGS; PYRIMIDINE NUCLEOSIDES;

EID: 79956298401     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01446-10     Document Type: Article

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