Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: A case control study

BMC Medical Genetics

Volumn 7, Issue , 2006, Pages

  Ogata, Toru ^a   Gregoire, Lucie ^b   Goddard, Katrina A B ^c   Skunca, Magdalena ^a   Tromp, Gerard ^a   Lancaster, Wayne D ^a   Parrado, Antonio R ^c   Lu, Qing ^c   Shibamura, Hidenori ^a   Sakalihasan, Natzi ^d   Limet, Raymond ^d   MacKean, Gerald L ^e   Arthur, Claudette ^e   Sueda, Taijiro ^f   Kuivaniemi, Helena ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d UNIVERSITY OF LIÈGE   (Belgium)

^e DALHOUSIE UNIVERSITY   (Canada)

^f HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DQA ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DQB3 ANTIGEN; HLA DQB4 ANTIGEN; HLA DR ANTIGEN; UNCLASSIFIED DRUG;

ABDOMINAL AORTA ANEURYSM; ALLELE; ARTICLE; AUTOIMMUNITY; BELGIUM; CANADA; CASE CONTROL STUDY; CONTROLLED STUDY; ECHOGRAPHY; EVIDENCE BASED MEDICINE; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; HAPLOTYPE; HUMAN; HYBRIDIZATION; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE;

AORTIC ANEURYSM, ABDOMINAL; BELGIUM; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HLA-DQ ALPHA-CHAINS; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; MALE; POLYMORPHISM, GENETIC;

EID: 33748339773     PISSN: 14712350     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-7-67     Document Type: Article

References (44)

1. Steinmetz EF, Buckley C, Thompson RW: Prospects for the medical management of abdominal aortic aneurysms. Vasc Endovascular Surg 2003, 37(3):151-163.
2. Hirose H, Tilson MD: Abdominal aortic aneurysm as an autoimmune disease. Ann N Y Acad Sci 2001, 947:416-418.
3. Brophy CM, Reilly JM, Smith GJ, Tilson MD: The role of inflammation in nonspecific abdominal aortic aneurysm disease. Ann Vasc Surg 1991, 5(3):229-233.
4. Koch AE, Haines GK, Rizzo RJ, Radosevich JA, Pope RM, Robinson PG, Pearce WH: Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response. Am J Pathol 1990, 137(5):1199-1213.
5. Price P, Witt C, Allcock R, Sayer D, Garlepp M, Kok CC, French M, Mallal S, Christiansen F: The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple Immunopathological diseases. Immunol Rev 1999, 167:257-274.
6. Simmonds MJ, Howson JM, Heward JM, Cordell HJ, Foxall H, Carr-Smith J, Gibson SM, Walker N, Tomer Y, Franklyn JA, Todd JA, Gough SC: Regression mapping of association between the human leukocyte antigen region and Graves disease. Am J Hum Genet 2005, 76(1):157-163.
7. Marsh SGE, Parham P, Barber LD: THE HLA Facts Book. San Diego, ACADEMIC PRESS; 2000:1-398.
8. Warrens A, Lechler R: HLA in health and disease. San Diego, Academic Press; 1999.
9. Trowsdale J, Powis SH: The MHC: relationship between linkage and function. Curr Opin Genet Dev 1992, 2(3):492-497.
10. Altmann DM: HLA-DQ associations with autoimmune disease. Autoimmunity 1992, 14(1):79-83.
11. Norrgard O, Cedergren B, Angquist KA, Beckman L: Blood groups and HLA antigens in patients with abdominal aortic aneurysms. Hum Hered 1984, 34(1):9-13.
12. Tilson MD, Ozsvath KJ, Hirose H, Xia S: A genetic basis for autoimmune manifestations in the abdominal aortic aneurysm resides in the MHC class II locus DR-beta-1. Ann N Y Acad Sci 1996, 800:208-215.
13. Rasmussen TE, Hallett JWJ, Metzger RL, Richardson DM, Harmsen WS, Goronzy JJ, Weyand CM: Genetic risk factors in inflammatory abdominal aortic aneurysms: polymorphic residue 70 in the HLA-DR B1 gene as a key genetic element. J Vasc Surg 1997, 25(2):356-364.
14. Hirose H, Takagi M, Miyagawa N, Hashiyada H, Noguchi M, Tada S, Kugimiya T, Tilson MD: Genetic risk factor for abdominal aortic aneurysm: HLA-DR2(15), a Japanese study. J Vasc Surg 1998, 27(3):500-503.
15. Hirose H, Tilson MD: Negative genetic risk factor for abdominal aortic aneurysm: HLA-DQ3, a Japanese study. J Vasc Surg 1999, 30(5):959-960.
16. Rasmussen TE, Hallett JWJ, Schulte S, Harmsen WS, O'Fallon WM, Weyand CM: Genetic similarity in inflammatory and degenerative abdominal aortic aneurysms: a study of human leukocyte antigen class II disease risk genes. J Vasc Surg 2001, 34(1):84-89.
17. Rasmussen TE, Hallett JWJ, Tazelaar HD, Miller VM, Schulte S, O'Falon WM, Weyand CM: Human leukocyte antigen class II immune response genes, female gender, and cigarette smoking as risk and modulating factors in abdominal aortic aneurysms. J Vasc Surg 2002, 35(5):988-993.
18. Sugimoto T, Sada M, Miyamoto T, Yao H: Genetic analysis on HLA loci in Japanese patients with abdominal aortic aneurysm. Eur J Vasc Endovasc Surg 2003, 26(2):215-218.
19. Monux G, Serrano FJ, Vigil P, De la Concha EG: Role of HLA-DR in the pathogenesis of abdominal aortic aneurysm. Eur J Vasc Endovasc Surg 2003, 26(2):211-214.
20. Johnston KW, Rutherford RB, Tilson MD, Shah DM, Hollier L, Stanley JC: Suggested standards for reporting on arterial aneurysms. Subcommittee on Reporting Standards for Arterial Aneurysms, Ad Hoc Committee on Reporting Standards, Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery. J Vasc Surg 1991, 13(3):452-458.
21. Baird PA, Sadovnick AD, Yee IM, Cole CW, Cole L: Sibling risks of abdominal aortic aneurysm. Lancet 1995, 346(8975):601-604.
22. Lawrence PF, Wallis C, Dobrin PB, Bhirangi K, Gugliuzza N, Galt S, Kraiss L: Peripheral aneurysms and arteriomegaly: is there a familial pattern? J Vasc Surg 1998, 28(4):599-605.
23. Lederle FA, Johnson GR, Wilson SE: Abdominal aortic aneurysm in women. J Vasc Surg 2001, 34(1):122-126.
24. Kuivaniemi H, Yoon S, Shibamura H, Skunca M, Vongpunsawad S, Tromp G: Primer-extension preamplified DNA is a reliable template for genotyping. Clin Chem 2002, 48(9):1601-1604.
25. HUGO Gene Nomenclature Committee. [http://www.gene.ucl.ac.uk/ nomenclature]
26. Kimura A, Dong RP, Harada H, Sasazuki T: DNA typing of HLA class II genes in B-lymphoblastoid cell lines homozygous for HLA. Tissue Antigens 1992, 40(1):5-12.
27. Gregoire L, Lawrence WD, Kukuruga D, Eisenbrey AB, Lancaster WD: Association between HLA-DQB1 alleles and risk for cervical cancer in African-American women. Int J Cancer 1994, 57(4):504-507.
28. Sham PC, Curtis D: Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann Hum Genet 1995, 59 (Pt 1):97-105.
29. Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA: Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 2002, 70(2):425-434.
30. Abecasis GR, Cookson WO: GOLD - graphical overview of linkage disequilibrium. Bioinformatics 2000, 16(2):182-183.
31. Ogata T, Shibamura H, Tromp G, Sinha M, Goddard KA, Sakalihasan N, Limet R, MacKean GL, Arthur C, Sueda T, Kuivaniemi H: Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms. J Vasc Surg 2005, 41:1036-1042.
32. Ernst CB: Abdominal aortic aneurysm. N Engl J Med 1993, 328(16):1167-1172.
33. St Leger AS, Spencely M, McCollum CN, Mossa M: Screening for abdominal aortic aneurysm: a computer assisted cost-utility analysis. Eur J Vasc Endovasc Surg 1996, 11(2):183-190.
34. Wilmink AB, Quick CR: Epidemiology and potential for prevention of abdominal aortic aneurysm. Br J Surg 1998, 85(2):155-162.
35. Majumder PP, St Jean PL, Ferrell RE, Webster MW, Steed DL: On the inheritance of abdominal aortic aneurysm. Am J Hum Genet 1991, 48(1):164-170.
36. Verloes A, Sakalihasan N, Koulischer L, Limet R: Aneurysms of the abdominal aorta: familial and genetic aspects in three hundred thirteen pedigrees. J Vasc Surg 1995, 21(4):646-655.
37. Kuivaniemi H, Shibamura H, Arthur C, Berguer R, Cole CW, Juvonen T, Kline RA, Limet R, Mackean G, Norrgard O, Pals G, Powell JT, Rainio P, Sakalihasan N, van Vlijmen-van Keulen C, Verloes A, Tromp G: Familial abdominal aortic aneurysms: collection of 233 multiplex families. J Vasc Surg 2003, 37(2):340-345.
38. Shibamura H, Olson JM, van Vlijmen-Van Keulen C, Buxbaum SG, Dudek DM, Tromp G, Ogata T, Skunca M, Sakalihasan N, Pals G, Limet R, MacKean GL, Defawe O, Verloes A, Arthur C, Lossing AG, Burnett M, Sueda T, Kuivaniemi H: Genome scan for familial abdominal aortic aneurysm using sex and family history as covariates suggests genetic heterogeneity and identifies linkage to chromosome 19q13. Circulation 2004, 109(17):2103-2108.
39. Campbell CD, Ogburn EL, Lunetta KL, Lyon HN, Freedman ML, Groop LC, Altshuler D, Ardlie KG, Hirschhorn JN: Demonstrating stratification in a European American population. Nat Genet 2005, 37(8):868-872.
40. Helgason A, Yngvadottir B, Hrafnkelsson B, Gulcher J, Stefansson K: An Icelandic example of the impact of population structure on association studies. Nat Genet 2005, 37(1):90-95.
41. Redondo MJ, Fain PR, Eisenbarth GS. Genetics of type 1A diabetes. Recent Prog Horm Res 2001, 56:69-89.
42. Marchini M, Antonioli R, Lleo A, Barili M, Caronni M, Origgi L, Vanoli M, Scorza R: HLA class II antigens associated with lupus nephritis in Italian SLE patients. Hum Immunol 2003, 64(4):462-468.
43. Beck S, Trowsdale J: The human major histocompatability complex: lessons from the DNA sequence. Annu Rev Genomics Hum Genet 2000, 1:117-137.
44. Beauchamp GK, Yamazaki K: HLA and mate selection in humans: commentary. Am J Hum Genet 1997, 61(3):494-496.