Albendazole induces apoptosis in adults and microfilariae of Setaria cervi

Experimental Parasitology

Volumn 128, Issue 3, 2011, Pages 236-242

  Nayak, A ^a   Gayen, P ^a   Saini, P ^a   Maitra, S ^a   Sinha Babu, S P ^a  

^a VISVA BHARATI UNIVERSITY   (India)

Author keywords

Albendazole (ABZ); Apoptosis; Lymphatic filariasis; Macrofilaricide; Microfilaria (Mf); Setaria cervi

Indexed keywords

ALBENDAZOLE; BETA TUBULIN;

ANTHELMINTIC ACTIVITY; APOPTOSIS; ARTICLE; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DNA FRAGMENTATION; FEMALE; MALE; MICROFILARIA; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; SETARIA CERVI;

ALBENDAZOLE; ANIMALS; ANTHELMINTICS; APOPTOSIS; CATTLE; DNA FRAGMENTATION; FEMALE; IN SITU NICK-END LABELING; MALE; MICROFILARIA; PERITONEAL CAVITY; SETARIA NEMATODE; SETARIASIS;

BOS; SETARIA CERVI;

EID: 79956156999     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2011.03.005     Document Type: Article

References (37)

1. Barrowman M.M., Marriner S.E., Bogan J.A. The binding and subsequent inhibition of tubulin polymerization in Ascaris suum (in vitro) by benzimidazole anthelmintics. Biochemical Pharmacology 1984, 33:3037-3040.
2. Belizario V.Y., Amarillo M.E., de Leon W.U., de los Reyes A.E., Bugayong M.G., Macatangay B.J.C. A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp. Bulletin of the World Health Organization 2003, 81:1.
3. Comley J.C.W., Rees M.J., Turner C.H., Jenkins D.C. Colorimetric quantitation of filarial viability. International Journal for Parasitology 1989, 19:77-83.
4. Conradt B., Horvitz H.R. The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2 like protein CED-9. Cell 1998, 93:519-529.
5. Cross H.F., Haarbrink M., Egerton G., Yazdanbakhsh M., Taylor M.J. Severe reactions to filarial chemotherapy and release of Wolbachia endosymbionts into blood. Lancet 2001, 358:1873-1875.
6. Datta S., Maitra S., Gayen P., Sinha Babu S.P. Absence of symbiotic Wolbachia endobacteria in Setaria cervi from Birbhum, West Bengal, India. Current Science 2007, 93:22-23.
7. Elard L., Humbert J.F. Importance of the mutation of amino acid 200 of the isotype 1 tubulin gene in the benzimidazole resistance of the small ruminant parasite Teladorsagia circumcincta. Parasitology Research 1999, 85:452-456.
8. Elard L., Comes A.M., Humbert J.F. Sequences of tubulin cDNA from benzimidazole-susceptible and resistant strains of Teladorsagia circumcincta, a nematode parasite of small ruminants. Molecular and Biochemical Parasitology 1996, 79:249-253.
9. Ellis H.M., Horvitz H.R. Genetic control of programmed cell death in the nematode C. elegans. Cell 1986, 44:817-829.
10. Hengartner M.O., Horvitz H.R. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 1994, 76:665-676.
11. WHO Global programme to eliminate lymphatic filariasis. The Weekly Epidemiological Record 2007, 82:361-380.
12. Horvitz, H.R., 2003. Worms, life, and death (Nobel Lecture) Review 4, 697-711.
13. Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis. A basic biological phenomenon with wide ranging implications in tissue kinetics. British Journal of Cancer 1972, 26:239-257.
14. Kisurina-Evgen'eva O.P., Bryantseva S.A., Shtil A.A., Onishchenko G.E. Antitubulin agents can initiate different apoptotic pathways. Cell Biophysics 2006, 51:771-775.
15. Kwa M.S.G., Veenstra J.G., Roos M.H. Benzimidazole resistance in Haemonchus contortus is correlated with a conserved mutation at amino acid 200 in beta-tubulin isotype 1. Molecular and Biochemical Parasitology 1993, 63:299-303.
16. Kwa M.S.G., Veenstra J.G., Roos M.H. Molecular characterisation of tubulin genes present in benzimidazole-resistant populations of Haemonchus contortus. Molecular and Biochemical Parasitology 1993, 60:133-144.
17. Lacey E. Mode of action of benzimidazoles. Parasitology Today 1990, 6:112-115.
18. Lacey E., Watson T.R. Structure-activity relationships of benzimidazole carbamates as inhibitors of mammalian tubulin, in vitro. Biochemical Pharmacology 1985, 34:1073-1077.
19. Li X., Wang J., Manley J.L. Loss of splicing factor ASF/SF-2 induces G2 cell cycle arrest and apoptosis but inhibits internucleosomal DNA fragmentation. Genes and Development 2005, 19:2705-2714.
20. Marr J.J., Nilsen T.W., Komuniecki R. Molecular Medical Parasitology 2003, Academic Press, San Diego.
21. Martin R.J. Modes of action of anthelmintic drugs (comment). The Veterinary Journal 1997, 154:11-34.
22. Molyneux D.H., Bradley M., Hoerauf A., Kyelem D., Taylor M.J. Mass drug treatment for lymphatic filariasis and onchocerciasis. Trends in Parasitology 2003, 19:516-522.
23. Moss D.K., Betin V.M., Soazig M., Lane J.D. A novel role of microtubules in apoptotic chromatin dynamics and cellular fragmentation. Journal of Cell Science 2006, 119:2362-2374.
24. Mukhopadhyay T., Sasaki J., Ramesh R., Roth J.A. Mebendazole elicits a potent anti-tumor effect on human cancer cell lines both in vitro and in vivo. Clinical Cancer Research 2002, 8:2963-2969.
25. Pene P., Mojon M., Garin J.P., Coulaud J.P., Rossignol J.F. Albendazole: a new broad spectrum anthelmintic. American Journal of Tropical Medicine and Hygiene 1982, 31:263-266.
26. Pourgholami M.H., Akhter J., Wang L., Lu Y., Morris D.L. Antitumor activity of albendazole against the human colorectal cancer cell line HT-29: in vitro and in a xenograft model of peritoneal carcinomatosis. Cancer Chemotherapy and Pharmacology 2005, 55:525-532.
27. Rao R., Weil G.J. In vitro effects of antibiotics on Brugia malayi worm survival and reproduction. The Journal of Parasitology 2002, 88:605-611.
28. Sasaki J., Ramesh R., Chada S., Gomyo Y., Roth J.A., Mukhopadhyay T. The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells. Molecular Cancer Therapeutics 2002, 1:1201-1209.
29. Schwab A.E., Boakye D.A., Kyelem D., Prichard R.K. Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment. American Journal of Tropical Medicine and Hygiene 2005, 73:234-238.
30. Silvestre A., Cabaret J. Mutation in position 247 of isotype 1 -tubulin gene of Trichostrongylid nematodes: role in benzimidazole resistance?. Molecular and Biochemical Parasitology 2002, 120:297-300.
31. Singhal K.C., Chandra O.M., Saxena P.N. An in vitro method for the screening of antifilarial agents using Setaria cervi as test organism. Japanese Journal of Pharmacology 1972, 22:175-179.
32. Su S.B., Motoo Y., Iovanna J.L., Berthezene P., Xie M.J., Mouri H., Ohtsubo K., Matsubara F., Sawabu N. Overexpression of p8 is inversely correlated with apoptosis in pancreatic cancer. Clinical Cancer Research 2001, 7:1320-1324.
33. Sulston J.E., Horvitz H.R. Post-embryonic cell lineages of the nematode Caenorhabditis elegans. Developmental Biology 1977, 56:110-156.
34. Sulston J.E., Schierenberg E., White J.G., Thomson J.N. The embryonic cell lineage of the nematode Caenorhabditis elegans. Developmental Biology 1983, 100:64-119.
35. Theodorides V.J., Gyerik R.J., Kingsbury W.D., Parish R.C. Anthelmintic activity of albendazole against liver flukes, tapeworms, lung and gastrointestinal roundworms. Experientia 1976, 32:702.
36. Wu Y.C., Stanfield G.M., Horvitz H.R. NUC-1, a Caenorhabditis elegans DNase II holomog, functions in an intermediate step of DNA degradation during apoptosis. Genes and Development 2000, 14:536-548.
37. Yuste V.J., Bayascas J.R., Llecha N., Sanchez-Lopez I., Boix J., Comella J.X. The absence of oligonucleosomal DNA fragmentation during apoptosis of IMR-5 neuroblastoma cells. The Journal of Biological Chemistry 2001, 276:22323-22331.