메뉴 건너뛰기




Volumn 31, Issue 4, 2011, Pages 1197-1204

Antitumor effect of novel HSP90 inhibitor NVP-AUY922 against oral squamous cell carcinoma

Author keywords

HSP90 inhibitor; NVP AUY922; Oral squamous cell carcinoma

Indexed keywords

5 (2,4 DIHYDROXY 5 ISOPROPYLPHENYL) 4 (4 MORPHOLINOMETHYLPHENYL) 3 ISOXAZOLECARBOXYLIC ACID ETHYLAMIDE; CASPASE 3; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HEAT SHOCK PROTEIN 70; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROTEIN KINASE B; PROTEIN S6; VASCULOTROPIN;

EID: 79956150123     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (41)

References (28)
  • 2
    • 51649093834 scopus 로고    scopus 로고
    • Recent advances in head and neck cancer
    • Haddad RI and Shin DM: Recent advances in head and neck cancer. N Engl J Med 359: 1143-1154, 2008.
    • (2008) N Engl J Med , vol.359 , pp. 1143-1154
    • Haddad, R.I.1    Shin, D.M.2
  • 3
    • 77955477214 scopus 로고    scopus 로고
    • Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression
    • Chen JS, Hsu YM, Chen CC, Chen LL, Lee CC and Huang TS: Secreted heat shock protein 90alpha induces colorectal cancer cell invasion through CD91/LRP-1 and NF-kappaB-mediated integrin alphaV expression. J Biol Chem 285: 25458-25466, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 25458-25466
    • Chen, J.S.1    Hsu, Y.M.2    Chen, C.C.3    Chen, L.L.4    Lee, C.C.5    Huang, T.S.6
  • 5
    • 33750710409 scopus 로고    scopus 로고
    • Mechanisms of disease: The role of heat-shock protein 90 in genitourinary malignancy
    • DOI 10.1038/ncpuro0604, PII NCPURO0604
    • Lattouf JB, Srinivasan R, Pinto PA, Linehan WM and Neckers L: Mechanisms of disease: the role of heat-shock protein 90 in genitourinary malignancy. Nat Clin Pract Urol 3: 590-601, 2006. (Pubitemid 44698094)
    • (2006) Nature Clinical Practice Urology , vol.3 , Issue.11 , pp. 590-601
    • Lattouf, J.-B.1    Srinivasan, R.2    Pinto, P.A.3    Linehan, W.M.4    Neckers, L.5
  • 7
    • 59649086503 scopus 로고    scopus 로고
    • SNX-2112, a selective HSP90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK
    • Okawa Y, Hideshima T, Steed P, Vallet S, Hall S, Huang K, Rice J, Barabasz A, Foley B, Ikeda H, Raje N, Kiziltepe T, Yasui H, Enatsu S and Anderson KC: SNX-2112, a selective HSP90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK. Blood 113: 846-855, 2009.
    • (2009) Blood , vol.113 , pp. 846-855
    • Okawa, Y.1    Hideshima, T.2    Steed, P.3    Vallet, S.4    Hall, S.5    Huang, K.6    Rice, J.7    Barabasz, A.8    Foley, B.9    Ikeda, H.10    Raje, N.11    Kiziltepe, T.12    Yasui, H.13    Enatsu, S.14    Anderson, K.C.15
  • 13
    • 0141484615 scopus 로고    scopus 로고
    • A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
    • DOI 10.1038/nature01913
    • Kamal A, Thao L, Sensintaffar J, Zhang L, Boehm MF, Fritz LC and Burrows FJ: A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 425: 407-410, 2003. (Pubitemid 37187270)
    • (2003) Nature , vol.425 , Issue.6956 , pp. 407-410
    • Kamal, A.1    Thao, L.2    Sensintaffar, J.3    Zhang, L.4    Boehm, M.F.5    Fritz, L.C.6    Burrows, F.J.7
  • 18
    • 77952551024 scopus 로고    scopus 로고
    • Discovery and development of Hsp90 inhibitors: A promising pathway for cancer therapy
    • Porter JR, Fritz CC and Depew KM: Discovery and development of Hsp90 inhibitors: a promising pathway for cancer therapy. Curr Opin Chem Biol 14: 412-420, 2010.
    • (2010) Curr Opin Chem Biol , vol.14 , pp. 412-420
    • Porter, J.R.1    Fritz, C.C.2    Depew, K.M.3
  • 20
    • 77956476510 scopus 로고    scopus 로고
    • 17-Allylamino-17-demethoxygeldanamycin induces down-regulation of critical HSP90 protein clients and results in cell cycle arrest and apoptosis of human urinary bladder cancer cells
    • Karkoulis PK, Stravopodis DJ, Margaritis LH and Voutsinas GE: 17-Allylamino-17-demethoxygeldanamycin induces down-regulation of critical HSP90 protein clients and results in cell cycle arrest and apoptosis of human urinary bladder cancer cells. BMC Cancer 10: 481, 2010.
    • (2010) BMC Cancer , vol.10 , pp. 481
    • Karkoulis, P.K.1    Stravopodis, D.J.2    Margaritis, L.H.3    Voutsinas, G.E.4
  • 21
    • 72249088827 scopus 로고    scopus 로고
    • HER-2 immunohistochemical expression in oral squamous cell carcinomas is associated with polysomy of chromosome 17, not HER-2 amplification
    • Papavasileiou D, Tosios K, Christopoulos P, Goutas N and Vlachodimitropoulos D: HER-2 immunohistochemical expression in oral squamous cell carcinomas is associated with polysomy of chromosome 17, not HER-2 amplification. Head Neck Pathol 3: 263-270, 2009.
    • (2009) Head Neck Pathol , vol.3 , pp. 263-270
    • Papavasileiou, D.1    Tosios, K.2    Christopoulos, P.3    Goutas, N.4    Vlachodimitropoulos, D.5
  • 22
    • 42949097680 scopus 로고    scopus 로고
    • ErbB2 and fatty acid synthase (FAS) expression in 102 squamous cell carcinomas of the tongue: Correlation with clinical outcomes
    • DOI 10.1016/j.oraloncology.2007.06.008, PII S1368837507001601
    • Silva SD, Perez DE, Alves FA, Nishimoto IN, Pinto CA, Kowalski LP and Graner E: ErbB2 and fatty acid synthase (FAS) expression in 102 squamous cell carcinomas of the tongue: correlation with clinical outcomes. Oral Oncol 44: 484-490, 2008. (Pubitemid 351608619)
    • (2008) Oral Oncology , vol.44 , Issue.5 , pp. 484-490
    • Silva, S.D.1    Perez, D.E.2    Alves, F.A.3    Nishimoto, I.N.4    Pinto, C.A.L.5    Kowalski, L.P.6    Graner, E.7
  • 23
    • 68649090008 scopus 로고    scopus 로고
    • Overview of current and future biologically based targeted therapies in head and neck squamous cell carcinoma
    • Matta A and Ralhan R: Overview of current and future biologically based targeted therapies in head and neck squamous cell carcinoma. Head Neck Oncol 1: 6, 2009.
    • (2009) Head Neck Oncol , vol.1 , pp. 6
    • Matta, A.1    Ralhan, R.2
  • 26
    • 42549158533 scopus 로고    scopus 로고
    • HIF-1alpha and STAT3 client proteins interacting with the cancer chaperone Hsp90: Therapeutic considerations
    • Kim HL, Cassone M, Otvos L Jr. and Vogiatzi P: HIF-1alpha and STAT3 client proteins interacting with the cancer chaperone HSP90: therapeutic considerations. Cancer Biol Ther 7: 10-14, 2008. (Pubitemid 351590444)
    • (2008) Cancer Biology and Therapy , vol.7 , Issue.1 , pp. 10-14
    • Kim, H.L.1    Cassone, M.2    Otvos Jr., L.3    Vogiatzi, P.4
  • 27
    • 34047215555 scopus 로고    scopus 로고
    • RACK1 vs. HSP90: Competition for HIF-1 alpha degradation vs. stabilization
    • Liu YV and Semenza GL: RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization. Cell Cycle 6: 656-659, 2007.
    • (2007) Cell Cycle , vol.6 , pp. 656-659
    • Liu, Y.V.1    Semenza, G.L.2
  • 28
    • 79956077516 scopus 로고    scopus 로고
    • Implication of heat-shock protein 90 (HSP90) in tumor angiogenesis: A molecular target for anti-angiogenic therapy?
    • Staufer K and Stoeltzing O: Implication of heat-shock protein 90 (HSP90) in tumor angiogenesis: A molecular target for anti-angiogenic therapy? Curr Cancer Drug Targets 10: 890-897, 2010.
    • (2010) Curr Cancer Drug Targets , vol.10 , pp. 890-897
    • Staufer, K.1    Stoeltzing, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.