Identification of amiodarone metabolites in human bile by ultraperformance liquid chromatography/quadrupole time-of-flight mass spectrometry

Drug Metabolism and Disposition

Volumn 39, Issue 6, 2011, Pages 1058-1069

  Deng, Pan ^a   You, Tiangeng ^b   Chen, Xiaoyan ^a   Yuan, Tao ^a   Huang, Haihua ^a   Zhong, Dafang ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b Key Laboratory of Arrhythmias of Ministry of Education   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYLAMIODARONE; 3' HYDROXYLAMIODARONE; 4 METHYLPYRAZOLE; 4' CARBOXYLAMIODARONE; AMIODARONE; DEETHYLAMIODARONE; DEIODINATED AMIODARONE; DRUG METABOLITE; N OXIDE METABOLITE; OMEGA CARBOXYLATE AMIODARONE; UNCLASSIFIED DRUG;

AGED; ARTICLE; BILIARY TRACT DRAINAGE; CARBOXYLATION; CASE REPORT; CONTROLLED STUDY; DEIODINATION; DRUG BILE LEVEL; DRUG GLUCURONIDATION; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG STRUCTURE; FEMALE; HEART ARRHYTHMIA; HEPATOBILIARY DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LIVER MICROSOME; MALE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUADRUPOLE MASS SPECTROMETRY; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

AGED; AGED, 80 AND OVER; AMIODARONE; ANTI-ARRHYTHMIA AGENTS; BILE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; MALE; MASS SPECTROMETRY; METABOLIC DETOXICATION, DRUG; MICROSOMES, LIVER; MOLECULAR STRUCTURE;

EID: 79956118493     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.110.037671     Document Type: Article

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