High blood lead levels compromise the total antioxidant status of normal healthy adults in a population in Karachi

Pakistan Journal of Medical Sciences

Volumn 27, Issue 2, 2011, Pages 371-374

  Iqbal, Mohammad Perwaiz ^a   Yakub, Mohsin ^a  

^a AGA KHAN UNIVERSITY   (Pakistan)

Author keywords

Blood lead; Lead pollution; Oxidative stress; Pakistani adults; Total antioxidant status

Indexed keywords

ANTIOXIDANT; LEAD;

ADULT; ARTICLE; BLOOD ANALYSIS; COHORT ANALYSIS; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; LEAD BLOOD LEVEL; LOWEST INCOME GROUP; MALE; PAKISTAN; POPULATION RESEARCH;

EID: 79956110228     PISSN: 1682024X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Kumar A, Sivakanesan R, Gunasekera S. Antioxidants, oxidative stress status and waist/hip ratio in normolipidaemic AMI patients. Pak J Med Sci. 2008;24(5):689-693.
2. Sharhan S, Normah H, Fatimah A, Fadilah RN, Rohi GA, Amin I, et al. Antioxidant intake and status, and oxidative stress in relation to breast cancer risk: A case-control study. Asian Pac J Cancer Prev. 2008;9:343-349.
3. Ahmad K. Facing up to Pakistan's cardiovascular challenge. Lancet. 2002;359:859.
4. Iqbal MP, Ishaq M, Mehboobali N. Increased levels of erythrocyte glutathione in acute myocardial infarction. J Pak Med Assoc. 2004;54:254-258.
5. Yakub M, Iqbal MP. Association of blood lead (Pb) and plasma homocysteine: A cross sectional survey in Karachi, Pakistan. PLoS ONE 2010;5(7):e11706-doi:10.1371/ journal.pone.0011706.
6. Menke A, Muntner P, Batuman V, Silbergeld EK, Guallar E. Blood lead below 0.48μmol/l (10μg/dl) and mortality among US adults. Circulation. 2006;114:1388-1394.
7. Kasperczyk S, Birkner E, Kasperczyk A, Zalejska-Fiolka J. Activity of superoxide dismutase and catalase in people protractedly exposed to lead compounds. Ann Agric Environ Med. 2004;11:291-296.
8. Yakub M, Iqbal MP, Kakepoto GN, Rafique G, Memon Y, Azam I, et al. High prevalence of mild hyperhomocysteinemia and folate, B12 and B6 deficiencies in an urban population in Karachi, Pakistan. Pak J Med Sci. 2010;26(4):923-929.
9. Bijoor AR, Sinha R, Venkatesh T. Low-levels of blood lead and antioxidant status. J Indian Society of Toxicology 2007;3(2): online ISSN:0973-3566.
10. Bansilal, Ali N, Afzal N, Khan TS, Shahjahan S. Antioxidant status in coronary heart disease (CHD) patients with type 2 diabetes mellitus. J Ayub Med Coll Abbottabad. 2007;19(4):98-101.
11. Szeto YT, Kwok TC, Benzie IF. Effects of a long-term vegetarian diet on biomarkers of antioxidant status and cardiovascular disease risk. Nutrition. 2004;20(10):863-866.
12. Codoner-Franch P, Lopez-Jaen AB, Muniz P, Sentandreu E, Belles VV. Mandarin juice improves the antioxidant status of hypercholesterolemic children. J Ped Gastro & Nutr. 2008;47:349-355.
13. Mannino DM, Homa DM, Matte T, Hernandez-Avila M. Active and passive smoking and blood lead levels in US adults: data from the third National Health and Nutrition Examination Survey. Nicotine Tob Res. 2005;7(4):557-564.
14. Aycicek A, Erel O, Kocyigit A. Decreased total antioxidant capacity and increased oxidative stress in passive smoker infants and their mothers. Pediatr Int. 2005;47(6):635-639.
15. Bruno RS, Ramakrishnan R, Montine TJ, Bray TM, Traber MG. α-Tocopherol disappearance is faster in cigarette smokers and is inversely related to their ascorbic acid status. Am J Clin Nutr. 2005;81:95-103.
16. Risal S, Adhikari D, Alurkar VM, Singh PP. Oxidative stress and antioxidant status in cardiovascular diseases in population of western Nepal. Kathmandu Univ Med J. 2006;4(3):271-274.
17. Wang XL, Rainwater DL, Vandeberg JF, Mitchell BD, Mahaney MC. Genetic contributions to plasma total antioxidant activity. Arterioscler Thromb Vasc Biol. 2001;21:1190.
18. Steinberg D, Witztum JL. Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis? Circulation. 2002;105:2107-2111.
19. Rahbar MH, White F, Agboatwalla M, Hozhabri S, Luby S. Factors associated with elevated blood lead concentrations in children in Karachi, Pakistan. Bull World Health Organ. 2002;80(10):769-775.