The nature of consciousness in the visually deprived brain

Frontiers in Psychology

Volumn 2, Issue FEB, 2011, Pages

  Kupers, Ron ^a   Pietrini, Pietro ^b   Ricciardi, Emiliano ^b   Ptito, Maurice ^c,d  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF PISA   (Italy)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d HVIDOVRE HOSPITAL   (Denmark)

Author keywords

Blindness; Consciousness; Cross modal plasticity; Qualia; Rewiring; Supramodality; Vision

Indexed keywords

EID: 79956102565     PISSN: None     EISSN: 16641078     Source Type: Journal    
DOI: 10.3389/fpsyg.2011.00019     Document Type: Review

References (130)

1. Amedi, A., Floel, A., Knecht, S., Zohary, E., and Cohen, L. G. (2004). Transcranial magnetic stimulation of the occipital pole interferes with verbal processing in blind subjects. Nat. Neurosci. 7, 1266-1270.
2. Amedi, A., Jacobson, G., Hendler, T., Malach, R., and Zohary, E. (2002). Convergence of visual and tactile shape processing in the human lateral occipital complex. Cereb. Cortex 12, 1202-1212.
3. Amedi, A., Malach, R., Hendler, T., Peled, S., and Zohary E. (2001). Visuo-haptic object-related activation in the ventral visual pathway. Nat. Neurosci. 4, 324-330.
4. Amedi, A., Raz, N., Pianka, P., Malach, R., and Zohary, E. (2003). Early 'visual' cortex activation correlates with superior verbal memory performance in the blind. Nat. Neurosci. 6, 758-766.
5. Bach-y-Rita, P., and Kercel, S. (2003). Sensory substitution and the humanmachine interface. Trends Cogn. Sci. 7, 541-546.
6. Baumgaertner, A., Buccino, G., Lange, R., McNamara, A., and Binkofski, F. (2007). Polymodal conceptual processing of human biological actions in the left inferior frontal lobe. Eur. J. Neurosci. 25, 881-889.
7. Bengtsson, S. L., Nagy, Z., Skare, S., Forsman, L., Forssberg, H., and Ullén, F. (2005). Extensive piano practicing has regionally specific effects on white matter development. Nat. Neurosci. 8, 1148-1150.
8. Bicchi, A., Scilingo, E. P., Ricciardi, E., and Pietrini, P. (2008). Tactile flow explains haptic counterparts of common visual illusions. Brain Res. Bull. 75, 737-741.
9. Bittar, R. G., Ptito, M., Faubert, J., Dumoulin, S. O., and Ptito, A. (1999). Activation of the remaining hemisphere following stimulation of the blind hemifield in hemispherectomized subjects. Neuroimage 10, 3339-3346.
10. Bonino, D., Ricciardi, E., Sani, L., Gentili, C., Vanello, N., Guazzelli, M., Vecchi, T., and Pietrini, P. (2008). Tactile spatial working memory activates the dorsal extrastriate cortical pathway in congenitally blind individuals. Arch. Ital. Biol. 146, 133-146.
11. Boroojerdi, B., Bushara, K. O., Corwell, B., Immisch, I., Battaglia, F., Muellbacher, W., and Cohen, L. G. (2000). Enhanced excitability of the human visual cortex induced by short-term light deprivation. Cereb. Cortex 10, 529-534.
12. Bronchti, G., Heil, P., Sadka, R., Hess, A., Scheich, H., and Wollberg, Z. (2002). Auditory activation of " visual" cortical areas in the blind mole rat (Spalax ehrenbergi). Eur. J. Neurosci. 16, 311-329.
13. Bruno, M. A., Vanhaudenhuyse, A., Schnakers, C., Boly, M., Gosseries, O., Demertzi, A., Majerus, S., Moonen, G., Hustinx, R., and Laureys, S. (2010). Visual fixation in the vegetative state: an observational case series PET study. BMC Neurol. 10:35. doi: 10.1186/1471-2377-10-35
14. Buccino, G., Binkofski, F., and Riggio, L. (2004a). The mirror neuron system and action recognition. Brain Lang. 89, 370-376.
15. Buccino, G., Vogt, S., Ritzl, A., Fink, G. R., Zilles, K., Freund, H. J., and Rizzolatti, G. (2004b). Neural circuits underlying imitation learning of hand actions: an event-related fMRI study. Neuron 42, 323-334.
16. Burton, H., Diamond, J. B., and McDermott, K. B. (2003). Dissociating cortical regions activated by semantic and phonological tasks: a FMRI study in blind and sighted people. J. Neurophysiol. 90, 1965-1982.
17. Burton, H., Sinclair, R. J., and McLaren, D. G. (2004). Cortical activity to vibrotactile stimulation: an fMRI study in blind and sighted individuals. Hum. Brain Mapp. 23, 210-228.
18. Burton, H., Snyder, A. Z., Conturo, T. E., Akbudak, E., Ollinger, J. M., and Raichle, M. E. (2002). Adaptive changes in early and late blind: a fMRI study of Braille reading. J. Neurophysiol. 87, 589-607.
19. Cattaneo, Z., Vecchi, T., Cornoldi, C., Mammarella, I., Bonino, D., Ricciardi, E., and Pietrini P. (2008). Imagery and spatial processes in blindness and visual impairment. Neurosci. Biobehav. Rev. 32, 1346-1360.
20. Chabot, N., Charbonneau, V., Laramée, M. E., Tremblay, R., Boire, D., and Bronchti, G. (2008). Subcortical auditory input to the primary visual cortex in anophthalmic mice. Neurosci. Lett. 433, 129-134.
21. Chebat, D. R., Rainville, C., Kupers, R., and Ptito, M. (2007). Alterations in right posterior hippocampus in early blind individuals. Neuroreport 18, 329-333.
22. Cohen, L. G., Weeks, R. A., Sadato, N., Celnik, P., Ishii, K., and Hallett, M. (1999). Period of susceptibility for cross-modal plasticity in the blind. Ann. Neurol. 45, 451-460.
23. Cowey, A. (2010). The blindsight saga. Exp. Brain Res. 200, 3-24.
24. Cowey, A., and Stoerig, P. (1995). Blindsight in monkeys. Nature 373, 247-249.
25. Cowey, A., and Walsh, V. (2000). Magnetically induced phosphenes in sighted, blind and blindsighted observers. Neuroreport 11, 3269-3273.
26. Dehaene, S., Changeux, J. P., Naccache, L., Sackur, J., and Sergent, C. (2006). Conscious, preconscious, and subliminal processing: a testable taxonomy. Trends Cogn. Sci. 10, 204-211.
27. Desgent, S., Boire, D., and Ptito, M. (2005). Distribution of calcium binding proteins in visual and auditory cortices of hamsters. Exp. Brain Res. 163, 159-172.
28. Desgent, S., Boire, D., and Ptito, M. (2010). Altered expression of parvalbumin and calbindin in interneurons within the primary visual cortex of neonatal enucleated hamsters. Neuroscience. doi: 10.1016/j.neuroscience.2010.10.016. [Epub ahead of print].
29. Draganski, B., Gaser, C., Busch, V., Schuierer, G., Bogdahn, U., and May, A. (2004). Neuroplasticity: changes in grey matter induced by training. Nature 427, 311-312.
30. Fabbri-Destro, M., and Rizzolatti, G. (2008). Mirror neurons and mirror systems in monkeys and humans. Physiology (Bethesda) 23, 171-179.
31. Falchier, A., Clavagnier, S., Barone, P., and Kennedy, H. (2002). Anatomical evidence of multimodal integration in primate striate cortex. J. Neurosci. 22, 5749-5759.
32. Fiehler, K., Burke, M., Bien, S., Röder, B., and Rösler, F. (2009). The human dorsal action control system develops in the absence of vision. Cereb. Cortex 19, 1-12.
33. Fishman, M. C., and Michael, P. (1973). Integration of auditory information in the cat's visual cortex. Vision Res. 13, 1415-1419.
34. Fortin, M., Voss, P.,Lord, C., Lassonde, M., Pruessner, J., Saint-Amour, D., Rainville, C., and Lepore, F. (2008). Wayfinding in the blind: larger hippocampal volume and supranormal spatial navigation. Brain 131, 2995-3005.
35. Frost, D. O., Boire, D., Gingras, G., and Ptito, M. (2000). Surgically created neural pathways mediate visual pattern discrimination. Proc. Natl. Acad. Sci. U.S.A. 97, 11068-11073.
36. Frost, D. O., and Metin, C. (1985). Induction of functional retinal projections to the somatosensory system. Nature 317, 162-164.
37. Fujii, T., Tanabe, H. C., Kochiyama, T., and Sadato, N. (2009). An investigation of cross-modal plasticity of effective connectivity in the blind by dynamic causal modeling of functional MRI data. Neurosci. Res. 65, 175-186.
38. Gaglianese, A., Sani, L., Roebroeck, A., Handjaras, G., Bernardi, G., Costagli, M., Ricciardi, E., and Pietrini, P. (2010). " fMRI functional and effective connectivity in humans supports a direct pathway from thalamus to hMT?," in Presented at the 16th Annual Meeting of the Organization for Human Brain Mapping, Barcelona.
39. Galati, G., Committeri, G., Spitoni, G., Aprile, T., Di Russo, F., Pitzalis, S., and Pizzamiglio, L. (2008). A selective representation of the meaning of actions in the auditory mirror system. Neuroimage 40, 1274-1286.
40. Gallese, V., Fadiga, L., Fogassi, L., and Rizzolatti, G. (1996). Action recognition in the premotor cortex. Brain 119, 593-609.
41. Gaser, C., and Schlaug, G. (2003). Brain structures differ between musicians and non-musicians. J. Neurosci. 23, 9240-9245.
42. Gauthier, I., Skudlarski, P., Gore, J. C., and Anderson, A. W. (2000). Expertise for cars and birds recruits brain areas involved in face recognition. Nat. Neurosci. 3, 191-197.
43. Gauthier, I., Tarr, M. J., Anderson, A. W., Skudlarski, P., and Gore, J. C. (1999). Activation of the middle fusiform 'face area' increases with expertise in recognizing novel objects. Nat. Neurosci. 2, 568-573.
44. Gazzola, V., Aziz-Zadeh, L., and Keysers, C. (2006). Empathy and the somatotopic auditory mirror system in humans. Curr. Biol. 16, 1824-1829.
45. Gougoux, F., Zatorre, R. J., Lassonde, M., Voss, P., and Lepore, F. (2005). A functional neuroimaging study of sound localization: visual cortex activity predicts performance in early-blind individuals. PLoS Biol. 3, e27. doi: 10.1371/j.pbio.0030027
46. Haxby, J. V., Gobbini, M. I., Furey, M. L., Ishai, A., Schouten, J. L., and Pietrini, P. (2001). Distributed and overlapping representations of faces and objects in ventral temporal cortex. Science 293, 2425-2430.
47. Haxby, J. V., Horwitz, B., Ungerleider, L., Maisog, J. M., Pietrini, P., and Grady, C. L. (1994). The functional organization of human extrastriate cortex: a PET-rCBF study of selective attention to faces and locations. J. Neurosci. 14, 6336-6353.
48. Hurley, S. L., and Noë, A. (2003). Neural plasticity and consciousness. Biol. Philos. 18, 131-168.
49. Hyvarinen, J., Hyvärinen, L., and Linnankoski, I. (1991). Modification of parietal association cortex and functional blindness after binocular deprivation in young monkeys. Exp. Brain Res. 42, 1-8.
50. Ishai, A. (2010). Seeing faces and objects with the " mind's eye" . Arch. Ital. Biol. 148, 1-9.
51. Ishai, A., Ungerleider, L. G., and Haxby, J. V. (2000). Distributed neural systems for the generation of visual images. Neuron 28, 979-990.
52. Ishai, A., Ungerleider, L. G., Martin, A., Schouten, J. L., and Haxby, J. V. (1999). Distributed representation of objects in the human ventral pathway. Proc. Natl. Acad. Sci. U.S.A. 96, 9379-9384.
53. James, T. W., Humphrey, G. K., Gati, J. S., Servos, P., Menon, R. S., and Goodale, M. A. (2002). Haptic study of threedimensional objects activates extrastriate visual areas. Neuropsychologia 40, 1706-1714.
54. James, W. (1890). Principles of Psychology. New York: Dover.
55. Kanwisher, N., McDermott, J., and Chun, M. M. (1997). The fusiform face area: a module in human extrastriate cortex specialized for face perception. J. Neurosci. 17, 4302-4311.
56. Klinge, C., Eippert, F., Röder, B., and Büchel, C. (2010). Corticocortical connections mediate primary visual cortex responses to auditory stimulation in the blind. J. Neurosci. 30, 12798-12805.
57. Kohler, E., Keysers, C., Umilta, M. A., Fogassi, L., Gallese, V., and Rizzolatti, G. (2002). Hearing sounds, understanding actions: action representation in mirror neurons. Science 297, 846-848.
58. Kupers, R., Chebat, D. R., Madsen, K. H., Paulson, O. B., and Ptito, M. (2010). Neural correlates of virtual route recognition in congenital blindness.Proc. Natl. Acad. Sci. U.S.A. 107, 12716-12721.
59. Kupers, R., Christensen, R., Grey, M., and Ptito, M. (2009). Glucose metabolism of the occipital cortex in early blind subjects. Soc. Neurosci. Abstr. 167.26.
60. Kupers, R., Fumal, A., de Noordhout, A. M., Gjedde, A., Schoenen, J., and Ptito, M. (2006). Transcranial magnetic stimulation of the visual cortex induces somatotopically organized qualia in blind subjects. Proc. Natl. Acad. Sci. U.S.A. 103, 13256-13260.
61. Kupers, R., Pappens, M., Ptito, M., and Fumal, A. (2007). rTMS of the occipital cortex abolishes Braille reading and repetition priming in blind subjects. Neurology 68, 691-693.
62. Lahav, A., Saltzman, E., and Schlaug, G. (2007). Action representation of sound: audiomotor recognition network while listening to newly acquired actions. J. Neurosci. 27, 308-314.
63. Lamme, V. A. (2006). Towards a true neural stance on consciousness. Trends Cogn. Sci. 10, 494-501.
64. Laureys, S., Faymonville, M. E., Peigneux, P., Damas, P., Lambermont, B., Del Fiore, G., Degueldre, C., Aerts, J., Luxen, A., Franck, G., Lamy, M., Moonen, G., and Maquet, P. (2002). Cortical processing of noxious somatosensory stimuli in the persistent vegetative state. Neuroimage 17, 732-741.
65. Leh, S. E., Chakravarty, M. M., and Ptito, A. (2008). The connectivity of the human pulvinar: a diffusion tensor imaging tractography study. Int. J. Biomed. Imaging. doi 10.11555/2008/789539
66. Leh, S. E., Johansen-Berg, H., and Ptito, A. (2006). Unconscious vision: new insights into the neuronal correlate of blindsight using diffusion tractography. Brain 129, 1822-1832.
67. Lotze, M., Scheler, G., Tan, H. R. M., Braun, C., and Birbaumer N. (2003). The musician's brain: functional imaging of amateurs and professionals during performance and imagery. Neuroimage 20, 1817-1829.
68. Lyckman, A. W., and Sur, M. (2002). Role of afferent activity in the development of cortical specification. Results Probl. Cell Differ. 39, 139-156.
69. Macaluso, E., Frith C. D., and Driver. J. (2000). Modulation of human visual cortex by crossmodal spatial attention. Science 289, 1206-1208.
70. Matteau, I., Kupers, R., and Ptito, M. (2008). Tactile shape recognition through the tongue in the congenitally blind. FENS. Abstr 2008; 4:153.8.p.83
71. Matteau, I., Kupers, R., Ricciardi, E., Pietrini, P., and Ptito, M. (2010). Beyond visual, aural and haptic movement perception: hMT? is activated by electrotactile motion stimulation of the tongue in sighted and in congenitally blind individuals. Brain Res. Bull. 82, 264-270.
72. McCarthy, G., Puce, A., Gore, J. C., and Allison, T. (1997). Face-specific processing in the human fusiform gyrus. J. Cogn. Neurosci. 9, 605-610.
73. Merabet, L. B., and Pascual-Leone, A. (2010). Neural reorganization following sensory loss: the opportunity of change. Nat. Rev. Neurosci. 11, 44-52.
74. Metin, C., and Frost, D. O. (1989). Visual responses of neurons in somatosensory cortex of hamsters with experimentally induced retinal projections to somatosensory thalamus. Proc. Natl. Acad. Sci. U.S.A. 86, 357-361.
75. Noppeney, U., Friston, K. J., Ashburner, J., Frackowiak, R., and Price, C. J. (2005). Early visual deprivation induces structural plasticity in gray and white matter. Curr. Biol. 15, 488-490.
76. O'Craven, K. M., and Kanwisher, N. (2000). Mental imagery of faces and places activates corresponding stimulus-specific brain regions. J. Cogn. Neurosci. 12, 1013-1023.
77. O'Regan, J. K., and Noë, A. (2001). A sensorimotor account of vision and visual consciousness. Behav. Brain Sci. 24, 939-973.
78. Owen, A. M., Schiff, N. D., and Laureys, S. (2009). " The assessment of conscious awareness in the vegetative state," in The Neurology of Consciousness, eds S. Laureys and G. Tononi (London: Academic Press), 163-172.
79. Pallas, S. L. (2001). Intrinsic and extrinsic factors that shape neocortical specification. Trends Neurosci. 24, 417-423.
80. Pallas, S. L. (2002). " Cross-modal plasticity as a tool for understanding the ontogeny and phylogeny of cerebral cortex," in Cortical Areas: Unity and Diversity, eds A. Schuz and R. Miller (London/ New York: Taylor and Francis Inc.), 245-271.
81. Pan, W. J., Wu, G., Li, C. X., Lin, F., Sun, J., and Lei, H. (2007). Progressive atrophy in the optic pathway and visual cortex of early blind Chinese adults: a voxel-based morphometry magnetic resonance imaging study. Neuroimage 37, 212-220.
82. Penfield, W., and Boldrey, E. (1937). Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain 60, 389-443.
83. Pietrini, P., Furey, M. L., Ricciardi, E., Gobbini, M. I., Wu, W. H., Cohen, L., and Guazzelli, M. Haxby, J. V. (2004). Beyond sensory images: object-based representation in the human ventral pathway. Proc. Natl. Acad. Sci. U.S.A. 101, 5658-5663.
84. Pietrini, P., Ptito, M., and Kupers, R. (2009). " Blindness and consciousness: new lights from the dark," in The Neurology of Consciousness, eds S. Laureys and G. Tononi (New York: Academic Press), 360-374.
85. Poirier, C., Collignon, O., Scheiber, C., Renier, L., Vanlierde, A., Tranduy, D., Veraart, C., and De Volder, A. G. (2006). Auditory motion perception activates visual motion areas in early blind subjects. Neuroimage 31, 279-285.
86. Ptito, A., and Leh, S. E. (2007). Neural substrates of blindsight after hemispherectomy. Neuroscientist 13, 506-518.
87. Ptito, M., and Desgent, S. (2006). " Sensory input-based adaptation and brain architecture," in Lifespan Development and the Brain, eds P. Baltes, P. Reuter-Lorenz, and F. Rösler (Cambridge University Press), 111-123.
88. Ptito, M., Fumal, A., de Noordhout, A. M., Schoenen, J., Gjedde, A., and Kupers, R. (2008a). TMS of the occipital cortex induces tactile sensations in the fingers of blind Braille readers. Exp. Brain Res. 184, 193-200.
89. Ptito, M., Schneider, F., Paulson, O. B., and Kupers, R. (2008b). Alterations of the visual pathways in congenital blindness. Exp. Brain Res. 87, 41-49.
90. Ptito, M., Giguère, J. F., Boire, D., Frost, D. O., and Casanova, C. (2001a). When the auditory cortex turns visual. Prog. Brain Res. 134, 447-458.
91. Ptito, M., Kupers, R., Faubert, J., and Gjedde, A. (2001b). Cortical representation of inward and outward radial motion in man. Neuroimage 14, 1409-1415.
92. Ptito, M., Moesgaard, S., Gjedde, A., and Kupers, R. (2005). Cross-modal plasticity revealed by electrotactile stimulation of the tongue in the congenitally blind. Brain 128, 606-614.
93. Radoeva, P. D., Prasad, S., Brainard, D. H., and Aguirre, G. K. (2008). Neural activity within area v1 reflects unconscious visual performance in a case of blindsight. J. Cogn. Neurosci. 20, 1927-1939.
94. Raz, N., Amedi, A., and Zohary, E. (2005). V1 activation in congenitally blind humans is associated with episodic retrieval. Cereb. Cortex 15, 1459-1468.
95. Raz, N., Striem, E., Pundak, G., Orlov, T., and Zohary, E. (2007). Superior serial memory in the blind: a case of cognitive compensatory adjustment. Curr. Biol. 17, 1129-1133.
96. Rebillard, G., Carlier, E., Rebillard, M., and Pujol, R. (1977). Enhancement of visual responses on the primary auditory cortex of the cat after an early destruction of cochlear receptors. Brain Res. 129, 162-164.
97. Renier, L. A., Anurova, I., De Volder, A. G., Carlson, S., VanMeter, J., and Rauschecker, J. P. (2010). Preserved functional specialization for spatial processing in the middle occipital gyrus of the early blind. Neuron 68, 138-148.
98. Ricciardi, E., Basso, D., Sani, L., Bonino, D., Vecchi, T., Pietrini, P., and Miniussi, C. (2011). Functional inhibition of the human MT? cortex affects non-visual motion perception: a repetitive transcranial magnetic stimulation study during tactile speed discrimination. Exp. Biol. Med. 236. (in press).
99. Ricciardi, E., Bonino, D., Gentili, C., Sani, L., Pietrini, P., and Vecchi, T. (2006a). Neural correlates of spatial working memory in humans: a functional magnetic resonance imaging study comparing visual and tactile processes. Neuroscience 139, 339-349.
100. Ricciardi, E., Sani, L., Gentili, C., Bonino, D., Vanello, N., Haxby, J. V., Seifritz, E., Guazzelli, M., Landini, L., Bicchi, A., Di Salle, F., and Pietrini, P. (2006b). Brain response to visual, tactile and auditory flow in sighted and blind individuals supports a supramodal functional organization in hMT??complex. Neuroimage 31(Suppl. 1), 512 TH-PM.
101. Ricciardi, E., Bonino, D., Sani, L., Vecchi, T., Guazzelli, M., Haxby, J. V., Fadiga, L., and Pietrini, P. (2009). Do we really need vision? How blind people " see" the actions of others. J. Neurosci. 29, 9719-9124.
102. Ricciardi, E., Vanello, N., Sani, L., Gentili, C., Scilingo, E. P., Landini, L., Guazzelli, M., Bicchi, A., Haxby, J. V., and Pietrini, P. (2007). The effect of visual experience on the development of functional architecture in hMT?. Cereb. Cortex 17, 2933-2939.
103. Rizzolatti, G. (2005). The mirror neuron system and its function in humans. Anat. Embryol. (Berl). 210, 419-421.
104. Rizzolatti, G., and Craighero, L. (2004). The mirror-neuron system. Annu. Rev. Neurosci. 27, 169-192.
105. Rizzolatti, G., and Fadiga, L. (1998). Grasping objects and grasping action meanings: the dual role of monkey rostroventral premotor cortex (area F5). Novartis Found. Symp. 218, 81-95; discussion 103.
106. Rizzolatti, G., Fadiga, L., Gallese, V., and Fogassi, L. (1996). Premotor cortex and the recognition of motor actions. Brain Res. Cogn. Brain Res. 3, 131-141.
107. Rizzolatti, G., and Sinigaglia, C. (2008). Further reflections on how we interpret the actions of others. Nature 455, 589.
108. Rockland, K. S., and Ojima, H. (2003). Multisensory convergence in calcarine visual areas in macaque monkey. Int. J. Psychophysiol. 50,19-26.
109. Röder, B., Stick, O., Bien, S., Neville, H., and Rösler, F. (2002). Speech processing activates visual cortex in congenitally blind humans. Eur. J. Neurosci. 16, 930-936.
110. Röder, B., Teder-Sälejärvi, W., Sterr, A., Rösler, F., Hillyard, S. A., and Neville, H. (1999). Improved auditory spatial tuning in blind humans. Nature 400, 162-166.
111. Sadato, N., Pascual-Leone, A., Grafman, J., Ibanez, V., Deiber, M. P., Dold, G., and Hallett, M. (1996). Activation of the primary visual cortex by Braille reading in blind subjects. Nature 380, 526-528.
112. Sani, L., Ricciardi, E., Gentili, C., Vanello, N., Haxby, J. V., and Pietrini, P. (2010). Effects of visual experience on the human MT? functional connectivity networks: an fMRI study of motion perception in sighted and congenitally blind individuals. Front. Syst. Neurosci. 4:159. doi: 10.3389/fnsys.2010.00159
113. Sathian, K., and Zangaladze, A. (2002). Feeling with the mind's eye: contribution of visual cortex to tactile perception. Behav. Brain Res. 135, 127-132.
114. Schmid, M. C., Mrowka, S. W., Turchi, J., Saunders, R. C., Wilke, M., Peters, A. J., Ye, F. Q., and Leopold, D. A. (2010). Blindsight depends on the lateral geniculate nucleus. Nature 466, 373-377.
115. Scholz, J., Klein, M. C., Behrens, T. E., and Johansen-Berg, H. (2009). Training induces changes in whitematter architecture. Nat. Neurosci. 12, 1370-1371.
116. Shimony, J. S., Burton, H., Epstein, A. A., McLaren, D. G., Sun, S. W., and Snyder, A. Z. (2006). Diffusion tensor imaging reveals white matter reorganization in early blind humans. Cereb. Cortex 16, 1653-1661.
117. Stevens, A. A., Snodgrass, M., Schwartz, D., and Weaver, K. (2007). Preparatory activity in occipital cortex in early blind humans predicts auditory perceptual performance. J. Neurosci. 27, 10734-10741.
118. Théoret, H., Boire, D., Herbin, M., and Ptito, M. (2001). Anatomical sparing in the superior colliculus of hemispherectomized monkeys. Brain Res. 16, 274-280.
119. Toldi, J., Rojik, I., and Fehér, O. (1994). Neonatal monocular enucleationinduced cross-modal effects observed in the cortex of adult rat. Neuroscience 62, 105-114.
120. Tomaiuolo, F., Ptito, M., Marzi, C. A., Paus, T., and Ptito, A. (1997). Blindsight in hemispherectomized patients as revealed by spatial summation across the vertical meridian. Brain 120, 795-803.
121. Tusa, R. J., and Ungerleider, L. G. (1985). The inferior longitudinal fasciculus: a reexamination in humans and monkeys. Ann. Neurol. 18, 583-591.
122. Ungerleider, L. G., and Mishkin, M. (1982). " Two cortical visual systems," in Analysis of Visual Behavior, eds D. J. Ingle, M. A. Goodale, and R. J. W. Mansfield (Cambridge, MA: MIT Press), 549-586.
123. Vecchi, T., Cattaneo, Z., Monegato, M., Pece, A., Cornoldi, C., and Pietrini, P. (2006). Why Cyclops could not compete with Ulysses: monocular vision and mental images. Neuroreport 17, 723-726.
124. von Melchner, L., Pallas, S. L., and Sur, M. (2000). Visual behaviour mediated by retinal projections directed to the auditory pathway. Nature 404, 871-876.
125. Wallace, M. T., Ramachandran, R., and Stein, B. E. (2004). A revised view of sensory cortical parcellation. Proc. Natl. Acad. Sci. U.S.A. 101, 2167-2172.
126. Watson, J. D., Myers, R., Frackowiak, R. S., Hajnal, J. V., Woods, R. P., Mazziota, J. C., Shipp, S., and Zeki, S. (1993). Area V5 of the human brain: evidence from a combined study using positron emission tomography and magnetic resonance imaging. Cereb. Cortex 3, 79-94.
127. Weeks, R., Horwitz, B., Aziz-Sultan, A., Tian, B., Wessinger, C. M., Cohen, L. G., Hallett, M., and Rauschecker, J. P. (2000). A positron emission tomographic study of auditory localization in the congenitally blind. J. Neurosci. 20, 2664-2672.
128. Weiskrantz, L., Warrington, E. K., Sanders, M. D., and Marshall, J. (1974). Visual capacity in the hemianopic field following a restricted cortical ablation. Brain 97, 709-728.
129. Wittenberg, G. F. Werhahn, K. J., Wassermann, E. M., Herscovitch, P., and Cohen, L. G. (2004). Functional connectivity between somatosensory and visual cortex in early blind humans. Eur. J. Neurosci. 20, 1923-1927.
130. Zangaladze, A., Epstein, C. M., Grafton, S. T., and Sathian, K. (1999). Involvement of visual cortex in tactile discrimination of orientation. Nature 401, 587-590.