Effects of FGF2 and FGF9 on osteogenic differentiation of bone marrow-derived progenitors

In Vitro Cellular and Developmental Biology - Animal

Volumn 47, Issue 4, 2011, Pages 294-301

  Kizhner, T ^a   Ben David, D ^a   Rom, E ^b   Yayon, A ^b   Livne, E ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b ProCore BioMed Ltd   (Israel)

Author keywords

ectopic bone formation; FGF2; FGF9; human bone marrow derived MSCs; in vivo transplants

Indexed keywords

ALIZARIN; ALPHA MINIMAL ESSENTIAL MEDIUM; ANTHRAQUINONE DERIVATIVE; FGF9 PROTEIN, MOUSE; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 9; ORGANIC COMPOUND;

ANIMAL; ARTICLE; BONE MARROW CELL; BONE REGENERATION; CELL DIFFERENTIATION; CULTURE TECHNIQUE; MESENCHYMAL STEM CELL; METHODOLOGY; MOUSE; NUDE MOUSE; PHYSIOLOGY;

ANIMALS; ANTHRAQUINONES; BONE MARROW CELLS; BONE REGENERATION; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 9; MESENCHYMAL STEM CELLS; MICE; MICE, NUDE; ORGANIC CHEMICALS;

MUS; MUS MUSCULUS;

EID: 79956081269     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11626-011-9390-y     Document Type: Article

References (44)

1. H Agata I Asahina, et al. 2007 Effective bone engineering with periosteum-derived cells J Dent Res 86 79 83 17189468 10.1177/154405910708600113 1:CAS:528:DC%2BD2sXhsV2ltLg%3D
2. FW Bloemers TJ Blokhuis, et al. 2003 Autologous bone versus calcium-phosphate ceramics in treatment of experimental bone defects J Biomed Mater Res B Appl Biomater 66 526 531 12861603 10.1002/jbm.b.10045 (Pubitemid 37517124)
3. EJ Caterson LJ Nesti, et al. 2002 Human marrow-derived mesenchymal progenitor cells: isolation, culture expansion, and analysis of differentiation Mol Biotechnol 20 245 256 11936255 10.1385/MB:20:3:245 1:CAS:528: DC%2BD38Xis1Ojtrw%3D (Pubitemid 34252636)
4. DC Colter R Class, et al. 2000 Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow Proc Natl Acad Sci USA 97 3213 3218 10725391 10.1073/pnas.070034097 1:CAS:528:DC%2BD3cXitlWqs7s%3D (Pubitemid 30183281)
5. L De Moerlooze C Dickson 1997 Skeletal disorders associated with fibroblast growth factor receptor mutations Curr Opin Genet Dev 7 378 385 9229114 10.1016/S0959-437X(97)80152-9 (Pubitemid 27292290)
6. L Ever RJ Zhao, et al. 2008 Fibroblast growth factor receptor 2 plays an essential role in telencephalic progenitors Dev Neurosci 30 306 318 18073459 10.1159/000112521 1:CAS:528:DC%2BD1cXhtFKjurrP
7. A Fakhry C Ratisoontorn, et al. 2005 Effects of FGF-2/-9 in calvarial bone cell cultures: differentiation stage-dependent mitogenic effect, inverse regulation of BMP-2 and noggin, and enhancement of osteogenic potential Bone 36 254 266 15780951 10.1016/j.bone.2004.10.003 1:CAS:528:DC%2BD2MXhslWks7c%3D (Pubitemid 40283582)
8. M Fujita Y Kinoshita, et al. 2005 Proliferation and differentiation of rat bone marrow stromal cells on poly(glycolic acid)-collagen sponge Tissue Eng 11 1346 1355 16259590 10.1089/ten.2005.11.1346 1:CAS:528:DC%2BD2MXhtFKlsL7E (Pubitemid 41636421)
9. V Govindarajan PA Overbeek 2006 FGF9 can induce endochondral ossification in cranial mesenchyme BMC Dev Biol 6 7 16504022 10.1186/1471-213X-6-7 (Pubitemid 43374322)
10. CA Gregory WG Gunn, et al. 2004 An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction Anal Biochem 329 77 84 15136169 10.1016/j.ab.2004.02.002 1:CAS:528:DC%2BD2cXjsl2hu7k%3D (Pubitemid 38596903)
11. Haynesworth S. E.; Goldberg V. M. et al. Diminution of the number of mesenchymal stem cells as a cause for skeletal aging. Musculoskeletal Soft-tissue Aging: Impact on Mobility. In: Buckwalter J. A., Goldberg V. M.; Y. W. SL-Y. (eds) Rosemont, American Academy of Orthopaedic Surgeons. pp. 79-87, 1994.
12. SE Haynesworth J Goshima, et al. 1992 Characterization of cells with osteogenic potential from human marrow Bone 13 81 88 1581112 10.1016/8756-3282(92)90364-3 1:STN:280:DyaK383ls1SlsA%3D%3D
13. D Hecht N Zimmerman, et al. 1995 Identification of fibroblast growth factor 9 (FGF9) as a high affinity, heparin dependent ligand for FGF receptors 3 and 2 but not for FGF receptors 1 and 4 Growth Factors 12 223 233 8619928 10.3109/08977199509036882 1:STN:280:DyaK287pt1Gquw%3D%3D
14. Y Hori S Inoue, et al. 2004 Effect of culture substrates and fibroblast growth factor addition on the proliferation and differentiation of rat bone marrow stromal cells Tissue Eng 10 995 1005 15363157 1:CAS:528: DC%2BD2cXnsVCqsLg%3D (Pubitemid 39223779)
15. SC Hung NJ Chen, et al. 2002 Isolation and characterization of size-sieved stem cells from human bone marrow Stem Cells 20 249 258 12004083 10.1634/stemcells.20-3-249
16. MM Hurley C Abreu, et al. 1994 Expression and regulation of basic fibroblast growth factor mRNA levels in mouse osteoblastic MC3T3-E1 cells J Biol Chem 269 9392 9396 8132679 1:CAS:528:DyaK2cXitlKls7s%3D (Pubitemid 24209272)
17. MM Hurley S Tetradis, et al. 1999 Parathyroid hormone regulates the expression of fibroblast growth factor-2 mRNA and fibroblast growth factor receptor mRNA in osteoblastic cells J Bone Miner Res 14 776 783 10320526 10.1359/jbmr.1999.14.5.776 1:CAS:528:DyaK1MXjtFKrtLc%3D (Pubitemid 29210604)
18. MA Ignelzi Jr W Wang, et al. 2003 Fibroblast growth factors lead to increased Msx2 expression and fusion in calvarial sutures J Bone Miner Res 18 751 759 12674336 10.1359/jbmr.2003.18.4.751 1:CAS:528:DC%2BD3sXivFKks7c%3D (Pubitemid 36899325)
19. RA Jackson V Nurcombe, et al. 2006 Coordinated fibroblast growth factor and heparan sulfate regulation of osteogenesis Gene 379 79 91 16797878 10.1016/j.gene.2006.04.028 1:CAS:528:DC%2BD28Xos12kurY%3D (Pubitemid 44262446)
20. E Jones D McGonagle 2008 Human bone marrow mesenchymal stem cells in vivo Rheumatology (Oxford) 47 126 131 10.1093/rheumatology/kem206 1:STN:280:DC%2BD1c%2FltFantw%3D%3D (Pubitemid 351168218)
21. N Kotobuki M Hirose, et al. 2004 Cultured autologous human cells for hard tissue regeneration: preparation and characterization of mesenchymal stem cells from bone marrow Artif Organs 28 33 39 14720286 10.1111/j.1525-1594.2004.07320. x (Pubitemid 38234242)
22. ZG Li P Mathew, et al. 2008 Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms J Clin Invest 118 2697 2710 18618013 10.1172/JCI33637C1 1:CAS:528:DC%2BD1cXpsVOktLo%3D
23. EA Luria ME Owen, et al. 1987 Bone formation in organ cultures of bone marrow Cell Tissue Res 248 449 454 3581153 10.1007/BF00218212 1:STN:280:DyaL2s3hsFyrtw%3D%3D (Pubitemid 17042743)
24. T Matsubara K Suardita, et al. 2005 Alveolar bone marrow as a cell source for regenerative medicine: differences between alveolar and iliac bone marrow stromal cells J Bone Miner Res 20 399 409 15746984 10.1359/JBMR.041117 1:CAS:528:DC%2BD2MXis1Knur8%3D (Pubitemid 40293488)
25. S Maurice S Srouji, et al. 2007 Isolation of progenitor cells from cord blood using adhesion matrices Cytotechnology 54 121 133 19003027 10.1007/s10616-007-9077-0 1:CAS:528:DC%2BD2sXotlSlsrc%3D (Pubitemid 47174820)
26. A Montero Y Okada, et al. 2000 Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation J Clin Invest 105 1085 1093 10772653 10.1172/JCI8641 1:CAS:528:DC%2BD3cXisFOlur8%3D (Pubitemid 30217693)
27. A Muraglia I Martin, et al. 1998 A nude mouse model for human bone formation in unloaded conditions Bone 22 131S 134S 9600769 10.1016/S8756- 3282(98)00009-X 1:STN:280:DyaK1c3mtFeqtA%3D%3D (Pubitemid 28223271)
28. DM Ornitz PJ Marie 2002 FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease Genes Dev 16 1446 1465 12080084 10.1101/gad.990702 1:CAS:528:DC%2BD38XltVGmtL8%3D (Pubitemid 34686327)
29. N Quarto MT Longaker 2008 Differential expression of specific FGF ligands and receptor isoforms during osteogenic differentiation of mouse adipose-derived stem cells (mASCs) recapitulates the in vivo osteogenic pattern Gene 424 130 140 18718860 10.1016/j.gene.2008.07.029 1:CAS:528: DC%2BD1cXhtF2ms7vP
30. N Quarto DC Wan, et al. 2008 Molecular mechanisms of FGF-2 inhibitory activity in the osteogenic context of mouse adipose-derived stem cells (mASCs) Bone 42 1040 1052 18420480 10.1016/j.bone.2008.01.026 1:CAS:528: DC%2BD1cXmtValur8%3D
31. M Reyes T Lund, et al. 2001 Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells Blood 98 2615 2625 11675329 10.1182/blood.V98.9.2615 1:CAS:528:DC%2BD3MXotVegs7s%3D
32. MG Sabbieti L Marchetti, et al. 1999 Prostaglandins regulate the expression of fibroblast growth factor-2 in bone Endocrinology 140 434 444 9886855 10.1210/en.140.1.434 1:CAS:528:DyaK1MXhtFWrsQ%3D%3D (Pubitemid 29011189)
33. I Sekiya BL Larson, et al. 2002 Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality Stem Cells 20 530 541 12456961 10.1634/stemcells.20-6- 530 (Pubitemid 35463066)
34. BJ Slater MD Kwan, et al. 2008 Mesenchymal cells for skeletal tissue engineering Expert Opin Biol Ther 8 885 893 18549320 10.1517/14712598.8.7.885 1:CAS:528:DC%2BD1cXntFOrsrY%3D (Pubitemid 352007001)
35. JR Smith R Pochampally, et al. 2004 Isolation of a highly clonogenic and multipotential subfraction of adult stem cells from bone marrow stroma Stem Cells 22 823 831 15342946 10.1634/stemcells.22-5-823 (Pubitemid 39166939)
36. LA Solchaga K Penick, et al. 2005 FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells J Cell Physiol 203 398 409 15521064 10.1002/jcp.20238 1:CAS:528: DC%2BD2MXjtVygtb8%3D (Pubitemid 40471774)
37. PA Sotiropoulou SA Perez, et al. 2006 Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells Stem Cells 24 462 471 16109759 10.1634/stemcells.2004-0331 (Pubitemid 44464816)
38. R Sullivan M Klagsbrun 1985 Purification of cartilage-derived growth factor by heparin affinity chromatography J Biol Chem 260 2399 2403 3838306 1:CAS:528:DyaL2MXhsVehu7c%3D (Pubitemid 15104846)
39. TC Toai HD Thao, et al. 2009 In vitro culture and differentiation of osteoblasts from human umbilical cord blood Cell Tissue Bank 11 269 280 19565355 10.1007/s10561-009-9141-4
40. S Tsutsumi A Shimazu, et al. 2001 Retention of multilineage differentiation potential of mesenchymal cells during proliferation in response to FGF Biochem Biophys Res Commun 288 413 419 11606058 10.1006/bbrc.2001.5777 1:CAS:528:DC%2BD3MXnsF2qt7o%3D (Pubitemid 33022499)
41. C van den Bos JD Mosca, et al. 1997 Human mesenchymal stem cells respond to fibroblast growth factors Hum Cell 10 45 50 9234064
42. CS Young H Abukawa, et al. 2005 Tissue-engineered hybrid tooth and bone Tissue Eng 11 1599 1610 16259613 10.1089/ten.2005.11.1599 1:CAS:528: DC%2BD2MXhtFKlsL7F (Pubitemid 41636444)
43. K Yu J Xu, et al. 2003 Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth Development 130 3063 3074 12756187 10.1242/dev.00491 1:CAS:528:DC%2BD3sXls1WltLc%3D (Pubitemid 36857252)
44. LY Yu Y Pei, et al. 2007 Effect of fibroblast growth factor 9 on Runx2 gene promoter activity in MC3T3-E1 and C2C12 cells Chin Med J (Engl) 120 491 495 1:CAS:528:DC%2BD2sXkvVKqtrw%3D (Pubitemid 46510761)